Gary B. Kaplan, MD

Professor, Psychiatry

Gary Kaplan
150 S Huntington Ave


Dr. Kaplan serves as the Director of the Mental Health Service and Chief of Psychiatry at VA Boston Healthcare System. His clinical and pre-clinical and research focus is within the neurobiology and neuropharmacology of addiction, schizophrenia, and conditioned fear. His research specifically examines conditioned drug reward and its extinction and is published in journals of neuroscience and pharmacology.

Dr. Kaplan currently serves on the editorial board the Journal of Clinical Pharmacology. His national role in psychiatry has been recognized by the American Psychiatric Association where he was conferred as a Distinguished Fellow. He is the lead author of a text for the American Psychiatric Press Inc. for psychiatric clinicians and residents entitled Brain Circuitry and Signaling in Psychiatry which examines the functional circuitry and neurochemical pathways in psychiatric illnesses.

Dr. Kaplan is a graduate of University of Pennsylvania and Drexel University College of Medicine (Hahnemann). His residency training in Psychiatry and post-doctoral research training in Pharmacology were at Tufts University School of Medicine.

Other Positions

  • Professor, Pharmacology & Experimental Therapeutics, Boston University School of Medicine
  • VA Boston Healthcare System
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences


  • Hahnemann University, MD
  • University of Pennsylvania, BA

Classes Taught

  • GMSMS710


  • Published on 7/15/2021

    Liverant GI, Gallagher MW, Arditte Hall KA, Rosebrock LE, Black SK, Kind S, Fava M, Kaplan GB, Kamholz BW, Pineles SL, Sloan DM. Suppression and acceptance in unipolar depression: Short-term and long-term effects on emotional responding. Br J Clin Psychol. 2021 Jul 15. PMID: 34268773.

    Read at: PubMed
  • Published on 11/2/2020

    Thompson BL, Oscar-Berman M, Kaplan GB. Opioid-induced structural and functional plasticity of medium-spiny neurons in the nucleus accumbens. Neurosci Biobehav Rev. 2021 01; 120:417-430. PMID: 33152423.

    Read at: PubMed
  • Published on 11/3/2017

    Kaplan GB, Leite-Morris KA, Wang L, Rumbika KK, Heinrichs SC, Zeng X, Wu L, Arena DT, Teng YD. Pathophysiological Bases of Comorbidity: Traumatic Brain Injury and Post-Traumatic Stress Disorder. J Neurotrauma. 2018 01 15; 35(2):210-225. PMID: 29017388.

    Read at: PubMed
  • Published on 1/12/2017

    Kobrin KL, Arena DT, Heinrichs SC, Nguyen OH, Kaplan GB. Dopamine D1 receptor agonist treatment attenuates extinction of morphine conditioned place preference while increasing dendritic complexity in the nucleus accumbens core. Behav Brain Res. 2017 03 30; 322(Pt A):18-28. PMID: 28089852.

    Read at: PubMed
  • Published on 6/19/2015

    Kobrin KL, Moody O, Arena DT, Moore CF, Heinrichs SC, Kaplan GB. Acquisition of morphine conditioned place preference increases the dendritic complexity of nucleus accumbens core neurons. Addict Biol. 2016 Nov; 21(6):1086-1096. PMID: 26096355.

    Read at: PubMed
  • Published on 2/13/2014

    Liverant GI, Sloan DM, Pizzagalli DA, Harte CB, Kamholz BW, Rosebrock LE, Cohen AL, Fava M, Kaplan GB. Associations among smoking, anhedonia, and reward learning in depression. Behav Ther. 2014 Sep; 45(5):651-63. PMID: 25022776.

    Read at: PubMed
  • Published on 1/7/2014

    Leite-Morris KA, Kobrin KL, Guy MD, Young AJ, Heinrichs SC, Kaplan GB. Extinction of opiate reward reduces dendritic arborization and c-Fos expression in the nucleus accumbens core. Behav Brain Res. 2014 Apr 15; 263:51-9. PMID: 24406724.

    Read at: PubMed
  • Published on 8/1/2013

    Harte CB, Liverant GI, Sloan DM, Kamholz BW, Rosebrock LE, Fava M, Kaplan GB. Association between smoking and heart rate variability among individuals with depression. Ann Behav Med. 2013 Aug; 46(1):73-80. PMID: 23436273.

    Read at: PubMed
  • Published on 7/31/2013

    Heinrichs SC, Leite-Morris KA, Rasmusson AM, Kaplan GB. Repeated valproate treatment facilitates fear extinction under specific stimulus conditions. Neurosci Lett. 2013 Sep 27; 552:108-13. PMID: 23916657.

    Read at: PubMed
  • Published on 4/6/2013

    Heinrichs SC, Leite-Morris KA, Guy MD, Goldberg LR, Young AJ, Kaplan GB. Dendritic structural plasticity in the basolateral amygdala after fear conditioning and its extinction in mice. Behav Brain Res. 2013 Jul 1; 248:80-4. PMID: 23570859.

    Read at: PubMed

View 55 more publications: View full profile at BUMC

View all profiles