David J. Waxman, PhD

Professor, Medicine

David Waxman
617.353.7401
5 Cummington St

Biography

David J. Waxman, PhD is a Biologist with extensive experience in the fields of biochemistry, molecular biology, and enzymology. Over the past 35 years, his lab has made seminal contributions to the research of cancer pharmacology and therapeutics, and steroid-metabolizing enzymes.
Dr. Waxman has spoken at over 130 conferences and has held appointments at a variety of universities including Harvard Medical School, MIT, and the Weizmann Institute.

Other Positions

  • Member, Genome Science Institute, Boston University
  • Professor, Biology, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University

Education

  • Harvard University, PhD
  • Harvard University, AM
  • Queens College, City University of New York, BA

Publications

  • Published on 3/24/2021

    Goldfarb CN, Waxman DJ. Global analysis of expression, maturation and subcellular localization of mouse liver transcriptome identifies novel sex-biased and TCPOBOP-responsive long non-coding RNAs. BMC Genomics. 2021 Mar 24; 22(1):212. PMID: 33761883.

    Read at: PubMed
  • Published on 2/9/2021

    Tabassum S, Tank A, Wang F, Karrobi K, Vergato C, Bigio IJ, Waxman DJ, Roblyer D. Optical scattering as an early marker of apoptosis during chemotherapy and antiangiogenic therapy in murine models of prostate and breast cancer. Neoplasia. 2021 03; 23(3):294-303. PMID: 33578267.

    Read at: PubMed
  • Published on 1/25/2021

    Hao P, Waxman DJ. STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes. Mol Cell Biol. 2021 01 25; 41(2). PMID: 33199496.

    Read at: PubMed
  • Published on 12/2/2020

    Melia T, Waxman DJ. Genetic factors contributing to extensive variability of sex-specific hepatic gene expression in Diversity Outbred mice. PLoS One. 2020; 15(12):e0242665. PMID: 33264334.

    Read at: PubMed
  • Published on 11/18/2020

    Tu S, Li M, Chen H, Tan F, Xu J, Waxman DJ, Zhang Y, Shao Z. MAnorm2 for quantitatively comparing groups of ChIP-seq samples. Genome Res. 2021 01; 31(1):131-145. PMID: 33208455.

    Read at: PubMed
  • Published on 11/17/2020

    Brocker CN, Kim D, Melia T, Karri K, Velenosi TJ, Takahashi S, Aibara D, Bonzo JA, Levi M, Waxman DJ, Gonzalez FJ. Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting. Nat Commun. 2020 11 17; 11(1):5847. PMID: 33203882.

    Read at: PubMed
  • Published on 7/17/2020

    Matthews BJ, Waxman DJ. Impact of 3D genome organization, guided by cohesin and CTCF looping, on sex-biased chromatin interactions and gene expression in mouse liver. Epigenetics Chromatin. 2020 07 17; 13(1):30. PMID: 32680543.

    Read at: PubMed
  • Published on 6/30/2020

    Tran AP, Ali Al-Radhawi M, Kareva I, Wu J, Waxman DJ, Sontag ED. Delicate Balances in Cancer Chemotherapy: Modeling Immune Recruitment and Emergence of Systemic Drug Resistance. Front Immunol. 2020; 11:1376. PMID: 32695118.

    Read at: PubMed
  • Published on 5/19/2020

    Lau-Corona D, Bae WK, Hennighausen L, Waxman DJ. Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2. PLoS Genet. 2020 05; 16(5):e1008796. PMID: 32428001.

    Read at: PubMed
  • Published on 4/1/2020

    Karri K, Waxman DJ. Widespread Dysregulation of Long Noncoding Genes Associated With Fatty Acid Metabolism, Cell Division, and Immune Response Gene Networks in Xenobiotic-exposed Rat Liver. Toxicol Sci. 2020 04 01; 174(2):291-310. PMID: 31926019.

    Read at: PubMed

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