Clint Makino, PhD

Associate Professor, Physiology & Biophysics

Clint Makino
617.358.8470
700 Albany Street

Biography

Dr. Clint Makino completed his PhD at Florida State University and postdoctoral studies at Stanford University School of Medicine. He is currently an Associate Professor of Physiology and Biophysics at Chobanian and Avedisian School of Medicine. He has published more than 50 journal papers and book chapters and serves on the editorial board of Frontiers in Molecular Neuroscience.

Other Positions

  • Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Education

  • Florida State University - Tallahassee, PhD
  • Duke University, BS

Publications

  • Published on 10/28/2021

    Klaus C, Caruso G, Gurevich VV, Hamm HE, Makino CL, DiBenedetto E. Phototransduction in retinal cones: Analysis of parameter importance. PLoS One. 2021; 16(10):e0258721. PMID: 34710119.

    Read at: PubMed
  • Published on 10/14/2020

    Caruso G, Klaus CJ, Hamm HE, Gurevich VV, Makino CL, DiBenedetto E. Position of rhodopsin photoisomerization on the disk surface confers variability to the rising phase of the single photon response in vertebrate rod photoreceptors. PLoS One. 2020; 15(10):e0240527. PMID: 33052986.

    Read at: PubMed
  • Published on 12/5/2019

    Caruso G, Gurevich VV, Klaus C, Hamm H, Makino CL, DiBenedetto E. Local, nonlinear effects of cGMP and Ca2+ reduce single photon response variability in retinal rods. PLoS One. 2019; 14(12):e0225948. PMID: 31805112.

    Read at: PubMed
  • Published on 2/15/2019

    Makino CL, Duda T, Pertzev A, Isayama T, Geva P, Sandberg MA, Sharma RK. Modes of Accessing Bicarbonate for the Regulation of Membrane Guanylate Cyclase (ROS-GC) in Retinal Rods and Cones. eNeuro. 2019 Jan-Feb; 6(1). PMID: 30783616.

    Read at: PubMed
  • Published on 1/1/2018

    Makino CL, Duda T, Pertzev A, Sharma RK. Experimental Approaches for Defining the Role of the Ca2+-Modulated ROS-GC System in Retinal Rods of Mouse. Methods Mol Biol. 2018; 1753:129-158. PMID: 29564786.

    Read at: PubMed
  • Published on 9/15/2016

    Sharma RK, Duda T, Makino CL. Integrative Signaling Networks of Membrane Guanylate Cyclases: Biochemistry and Physiology. Front Mol Neurosci. 2016; 9:83. PMID: 27695398.

    Read at: PubMed
  • Published on 1/28/2016

    Duda T, Pertzev A, Makino CL, Sharma RK. Bicarbonate and Ca(2+) Sensing Modulators Activate Photoreceptor ROS-GC1 Synergistically. Front Mol Neurosci. 2016; 9:5. PMID: 26858600.

    Read at: PubMed
  • Published on 3/12/2015

    Duda T, Wen XH, Isayama T, Sharma RK, Makino CL. Bicarbonate Modulates Photoreceptor Guanylate Cyclase (ROS-GC) Catalytic Activity. J Biol Chem. 2015 Apr 24; 290(17):11052-60. PMID: 25767116.

    Read at: PubMed
  • Published on 3/6/2015

    Sharma RK, Baehr W, Makino CL, Duda T. Ca(2+) and Ca(2+)-interlocked membrane guanylate cyclase signal modulation of neuronal and cardiovascular signal transduction. Front Mol Neurosci. 2015; 8:7. PMID: 25798085.

    Read at: PubMed
  • Published on 7/1/2014

    Isayama T, Chen Y, Kono M, Fabre E, Slavsky M, DeGrip WJ, Ma JX, Crouch RK, Makino CL. Coexpression of three opsins in cone photoreceptors of the salamander Ambystoma tigrinum. J Comp Neurol. 2014 Jul 01; 522(10):2249-65. PMID: 24374736.

    Read at: PubMed

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