Brian W. Jack, MD

Professor, Family Medicine

Brian Jack


Brian Jack, MD, is Professor and Chair of the Department of Family Medicine at Boston University School of Medicine and Boston Medical Center. Dr. Jack graduated from the University of Massachusetts Medical School and completed his residency training at the Brown University. He completed a fellowship at the University of Washington. Dr. Jack came to BU and Boston Medical Center in 1997 as the founding Vice Chair of the Department of Family Medicine. He has authored over 140 peer-reviewed articles or book chapters, reviewed papers for major medical journals, served on NICHHD, HRSA and AHRQ grant review panels. He is PI on grants from HRSA, NHLBI, PCORI, AHRQ, NIMHD, Global Fund, PEPFAR, EU and the Kellogg, Izumi, OSISA, and BC/BS Foundations, and others.

His research team has developed the “ReEngineered Discharge” (RED), adapted by the National Quality Forum as a national “Safe Practice”. RED is being used in all states and in over 10 countries. He completed projects with AHRQ funding including “Reengineering the Hospital Discharge for Patient Safety” which provided an in-depth analysis of the hospital discharge process. RED was then tested in Testing the Re-Engineered Hospital Discharge a RCT funded by AHRQ in the “Partners in Patient Safety” grants. Dissemination and implementation of RED was explored in an Action RFTO entitled Avoiding Readmissions in Hospitals Serving Diverse patients. Building on a RO1 from NHLBI with colleague Tim Bickmore of Northeastern University, he developed a health IT system to deliver RED at the bedside (the “Louise” system). Dr. Jack completed an AHRQ funded project entitled “Virtual Patient Advocates to Reduce Ambulatory Drug Events” that adapted Louise to be used by patients online when they went home from the hospital. He completed a project to design a tool kit describing the RED process and studied the barriers to RED implementation. New projects include a RCT of a mental health intervention to reduce rehospitalizations for those with depressive symptoms and an exploration of the causes of readmission from the patient perspective that focuses on mental health and the social determinants of care (Projecct ACHIEVE).

Dr. Jack received the 2008 CDC “Partner in Public Health Improvement” award for his work as leader of the CDC’s Select Panel on the Content of Preconception Care. He has completed work to design a preconception HIT system (Gabby) to assist in the provision of this care (AHRQ, HRSA MCHB, Kellogg) and is beginning a RCT to study its impact (NIMHD).

He received the 2013 Peter F. Drucker Award for Non-Profit Innovation, the “Patient Care Award for Excellence in Patent Education Innovation” award, the AHRQ “Patient Safety Investigator” award, and the “Best Research Paper of the Year” award of the Society of Teachers of Family Medicine. He was selected to HealthLeaders magazines annual “People Who Make Healthcare Better” list and one of Boston’s “Best Doctors” in each of 2010-2017. His Annals of Internal Medicine article describing RED is listed in the book “50 Studies Every Physician Should Know” and was the recipient of the Journal for Healthcare Quality Impact Article of the Year for the article, “How Hospitals Reengineer Their Discharge Processes to Reduce Readmissions.” In 2013 he was elected to the National Academy of Medicine.

Dr. Jack has also been active in the worldwide development of family medicine. He is Director of the Lesotho Boston Health Alliance, a Kellogg Foundation funded program that aims to improve the quality of district health services in Lesotho. He is a founding member of the AAFP’s Center for International Initiatives. He spent a sabbatical year in Budapest, Hungary in 1995 where he received a special citation from the mayor of Budapest. He taught in Jordan, Pakistan and Saudi Arabia and has worked on development of family medicine in Lesotho, Albania, Jordan, Romania, and Vietnam.


  • University of Massachusetts Medical School, MD
  • Brown University, MA
  • Clark University, BA


  • Published on 4/20/2020

    Walker R, Drakeley S, Julce C, Sidduri N, Bickmore T, Skouteris H, Jack B, Boyle J. Assessing the potential of a Virtual Patient Advocate to provide preconception care and health advice to women living in Australia. J Dev Orig Health Dis. 2020 Apr 20; 1-9. PMID: 32308183.

    Read at: PubMed
  • Published on 3/18/2020

    Hill B, Skouteris H, Boyle JA, Bailey C, Walker R, Thangaratinam S, Sundseth H, Stephenson J, Steegers E, Redman LM, Montanaro C, Lim S, Jorgensen L, Jack B, Borges ALV, Bergmeier HJ, Baxter JB, Harrison CL, Teede HJ. Health in Preconception, Pregnancy and Postpartum Global Alliance: International Network Pregnancy Priorities for the Prevention of Maternal Obesity and Related Pregnancy and Long-Term Complications. J Clin Med. 2020 Mar 18; 9(3). PMID: 32197374.

    Read at: PubMed
  • Published on 12/2/2019

    Hill B, Skouteris H, Teede HJ, Bailey C, Baxter JB, Bergmeier HJ, Borges ALV, Harrison CL, Jack B, Jorgensen L, Lim S, Montanaro C, Redman L, Steegers E, Stephenson J, Sundseth H, Thangaratinam S, Walker R, Boyle JA. Health in Preconception, Pregnancy and Postpartum Global Alliance: International Network Preconception Research Priorities for the Prevention of Maternal Obesity and Related Pregnancy and Long-Term Complications. J Clin Med. 2019 Dec 02; 8(12). PMID: 31810312.

    Read at: PubMed
  • Published on 9/24/2019

    McCloskey L, Quinn E, Ameli O, Heeren T, Craig M, Lee-Parritz A, Iverson R, Jack B, Bernstein JA. Interrupting the Pathway from Gestational Diabetes Mellitus to Type 2 Diabetes: The Role of Primary Care. Womens Health Issues. 2019 Nov - Dec; 29(6):480-488. PMID: 31562051.

    Read at: PubMed
  • Published on 3/26/2019

    Skouteris H, Teede HJ, Thangaratinam S, Bailey C, Baxter JA, Bergmeier HJ, Harrison C, Hill B, Jack B, Jorgensen L, Lim S, Matsaseng T, Montanaro C, Steegers E, Stephenson J, Sundseth H, Vilela Borges AL, Walker R, Redman L, Boyle J. Commentary: Obesity and Weight Gain in Pregnancy and Postpartum: an Evidence Review of Lifestyle Interventions to Inform Maternal and Child Health Policies. Front Endocrinol (Lausanne). 2019; 10:163. PMID: 30972021.

    Read at: PubMed
  • Published on 3/25/2019

    Bernstein J, Lee-Parritz A, Quinn E, Ameli O, Craig M, Heeren T, Iverson R, Jack B, McCloskey L. After Gestational Diabetes: Impact of Pregnancy Interval on Recurrence and Type 2 Diabetes. Biores Open Access. 2019; 8(1):59-64. PMID: 30923644.

    Read at: PubMed
  • Published on 10/18/2018

    Roberts S, Moore LC, Jack B. Improving discharge planning using the re-engineered discharge programme. J Nurs Manag. 2019 Apr; 27(3):609-615. PMID: 30223308.

    Read at: PubMed
  • Published on 9/1/2018

    Cancino RS, Jack BW. Family Medicine Hospitalists Three Years Out of Residency: Career Flexibility or a Threat to Office-Based Family Medicine? J Am Board Fam Med. 2018 Sep-Oct; 31(5):677-679. PMID: 30201662.

    Read at: PubMed
  • Published on 5/8/2018

    Bernstein J, Quinn E, Ameli O, Craig M, Heeren T, Iverson R, Jack B, Lee-Parritz A, Mccloskey L. Onset of T2DM after gestational diabetes: What the prevention paradox tells us about risk. Prev Med. 2018 08; 113:1-6. PMID: 29746972.

    Read at: PubMed
  • Published on 5/1/2018

    Mitchell SE, Laurens V, Weigel GM, Hirschman KB, Scott AM, Nguyen HQ, Howard JM, Laird L, Levine C, Davis TC, Gass B, Shaid E, Li J, Williams MV, Jack BW. Care Transitions From Patient and Caregiver Perspectives. Ann Fam Med. 2018 05; 16(3):225-231. PMID: 29760026.

    Read at: PubMed

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