Brian W. Jack, MD

Professor, Family Medicine

Brian Jack


Brian Jack, MD, is Professor and former Chair of the Department of Family Medicine at Boston University School of Medicine. He is Director of the Boston University Center for Health System Design & Implementation, a center within the Institute for Health System Innovation & Policy.
Dr. Jack graduated from the University of Massachusetts Medical School and completed his residency at Brown University. He completed a fellowship at the University of Washington. He came to BU in 1997 as the founding Vice Chair of the Department of Family Medicine. He authored over 170 peer-reviewed articles or book chapters, reviewed papers for major medical journals, and served on NICHHD, HRSA and AHRQ grant review panels. He was PI on grants from NHLBI, NIMHD, Fogarty Center, AHRQ, PCORI, HRSA, European Union, Global Fund, and the Dreyfus, Kellogg, Kirby and Blue Cross Blue Shield Foundations.
His research team has developed the “ReEngineered Discharge” (Project RED), adapted by the National Quality Forum as a national safe practice. RED is used in many hospitals throughout the US and internationally. He completed projects with AHRQ funding to conduct an in-depth analysis of the hospital discharge process. The article describing the RCT testing RED is listed in the book “50 Studies Every Physician Should Know.” He explored implementation of RED in a project in 10 hospitals across the US (AHRQ). With colleague Tim Bickmore of Northeastern University, he developed a conversational agent system to deliver RED at the bedside called “Louise” (NHLBI) that was highlighted on the front page of the Wall Street Journal. Dr. Jack then completed AHRQ funded projects to adapt Louise for use by patients being discharged from the hospital and to design a tool kit describing the RED processes Two PCORI funded projects explored causes of readmission from the patient perspective, and explored the optimal transitional care components with colleagues from the University of Kentucky (Project ACHIEVE). His team is now completing an RCT of a mental health intervention to reduce rehospitalizations for those with depressive symptoms (AHRQ R01, Blue Cross/Blue Shield Foundation).
In 1990, Dr. Jack published a paper in JAMA describing the new concept of preconception care. He received the 2008 CDC “Partner in Public Health Improvement” award for his work with the CDC’s Select Panel on the Content of Preconception Care that helped define the content of preconception care. He designed a preconception care health IT system (Gabby) to assist in the delivery of preconception care (AHRQ, Kellogg) and conducted an RCT of its impact (HRSA MCHB, NIMHD R01) published in The Lancet Digital Health in 2020. He is now studying the implementation of Gabby into Healthy Start sites and community health centers (AHRQ), culturally adapting the system to the southern African country of Lesotho (Fogarty Center) and adapting the system to men (Kellogg).
Dr. Jack received the Peter F. Drucker Award for Non-Profit Innovation in 2013. He received the AHRQ “Patient Safety Investigator” award and was named one of AHRQ grantees “whose work has led to significant changes in health care policy and notably influenced research and practice.” He received the “Patient Care Award for Excellence in Patent Education Innovation”, the “Best Research Paper of the Year” award, and the Gabriel Smilkstein Award for career work in global health from the Society of Teachers of Family Medicine. HealthLeaders magazines selected him to its annual “People Who Make Healthcare Better” list, and his 2016 article in the Journal for Healthcare Quality was the Impact Article of the Year. He was one of Boston’s “Best Doctors” in each of 2010-2015. He was elected to the National Academy of Medicine in 2013.
Dr. Jack is active in the worldwide development of family medicine. He is Director of the Lesotho Boston Health Alliance (LeBoHA) that aims to increase human resources in the health sector in Lesotho. Over 18 years LeBoHA initiated the first physician-training program in the country. He is a founding member of the AAFP’s Center for International Initiatives and received the Gabriel Smilkstein Award for global family medicine education. He spent a sabbatical year in Budapest, Hungary in 1995 where he received a special citation from the mayor of Budapest. He taught in Jordan and Pakistan and worked to help develop family medicine in Albania, Jordan, Romania, and Vietnam.


  • University of Massachusetts Medical School, MD
  • Brown University, MA
  • Clark University, BA


  • Published on 6/7/2021

    Kramer J, Yinusa-Nyahkoon L, Olafsson S, Penti B, Woodhams E, Bickmore T, Jack BW. Black Men's Experiences With Health care: Individuals' Accounts of Challenges, Suggestions for Change, and the Potential Utility of Virtual Agent Technology to Assist Black Men With Health Management. Qual Health Res. 2021 Jun 07; 10497323211013323. PMID: 34092141.

    Read at: PubMed
  • Published on 2/3/2021

    McGuire CM, Fatusin BB, Kodicherla H, Yakubu K, Ameh P, van Waes A, Rhoad E, Jack BW, Scott NA. Implementation of Online Research Training and Mentorship for Sub-Saharan African Family Physicians. Ann Glob Health. 2021 02 03; 87(1):13. PMID: 33598411.

    Read at: PubMed
  • Published on 1/19/2021

    Gardiner P, Bickmore T, Yinusa-Nyahkoon L, Reichert M, Julce C, Sidduri N, Martin-Howard J, Woodhams E, Aryan J, Zhang Z, Fernandez J, Loafman M, Srinivasan J, Cabral H, Jack BW. Using Health Information Technology to Engage African American Women on Nutrition and Supplement Use During the Preconception Period. Front Endocrinol (Lausanne). 2020; 11:571705. PMID: 33584534.

    Read at: PubMed
  • Published on 10/19/2020

    McGuire CM, Riffenburg K, Malope S, Jack B, Borba CPC. Mixed-methods evaluation of family medicine research training and peer mentorship in Lesotho. Afr J Prim Health Care Fam Med. 2020 Oct 19; 12(1):e1-e17. PMID: 33181879.

    Read at: PubMed
  • Published on 9/21/2020

    Walter AW, Julce C, Sidduri N, Yinusa-Nyahkoon L, Howard J, Reichert M, Bickmore T, Jack BW. Study protocol for the implementation of the Gabby Preconception Care System - an evidence-based, health information technology intervention for Black and African American women. BMC Health Serv Res. 2020 Sep 21; 20(1):889. PMID: 32958031.

    Read at: PubMed
  • Published on 9/1/2020

    Jack BW, Bickmore T, Yinusa-Nyahkoon L, Reichert M, Julce C, Sidduri N, Martin-Howard J, Zhang Z, Woodhams E, Fernandez J, Loafman M, Cabral HJ. Improving the health of young African American women in the preconception period using health information technology: a randomised controlled trial. Lancet Digit Health. 2020 09; 2(9):e475-e485. PMID: 33328115.

    Read at: PubMed
  • Published on 8/10/2020

    Bergmeier HJ, Vandall-Walker V, Skrybant M, Teede HJ, Bailey C, Baxter JB, Borges ALV, Boyle JA, Everitt A, Harrison CL, Herrera M, Hill B, Jack B, Jones S, Jorgensen L, Lim S, Montanaro C, Redman LM, Stephenson J, Sundseth H, Thangaratinam S, Thynne P, Walker R, Skouteris H. Global Health in Preconception, Pregnancy and Postpartum Alliance: development of an international consumer and community involvement framework. Res Involv Engagem. 2020; 6:47. PMID: 32793390.

    Read at: PubMed
  • Published on 8/1/2020

    Bickmore T, Zhang Z, Reichert M, Julce C, Jack B. Promotion of Preconception Care Among Adolescents and Young Adults by Conversational Agent. J Adolesc Health. 2020 08; 67(2S):S45-S51. PMID: 32718515.

    Read at: PubMed
  • Published on 4/20/2020

    Walker R, Drakeley S, Julce C, Sidduri N, Bickmore T, Skouteris H, Jack B, Boyle J. Assessing the potential of a Virtual Patient Advocate to provide preconception care and health advice to women living in Australia. J Dev Orig Health Dis. 2021 04; 12(2):300-308. PMID: 32308183.

    Read at: PubMed
  • Published on 3/18/2020

    Hill B, Skouteris H, Boyle JA, Bailey C, Walker R, Thangaratinam S, Sundseth H, Stephenson J, Steegers E, Redman LM, Montanaro C, Lim S, Jorgensen L, Jack B, Borges ALV, Bergmeier HJ, Baxter JB, Harrison CL, Teede HJ. Health in Preconception, Pregnancy and Postpartum Global Alliance: International Network Pregnancy Priorities for the Prevention of Maternal Obesity and Related Pregnancy and Long-Term Complications. J Clin Med. 2020 Mar 18; 9(3). PMID: 32197374.

    Read at: PubMed

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