Barbara A. Corkey, PhD

Professor, Medicine

Barbara Corkey
(617) 638-7091
650 Albany St Evans Biomed Research Ctr

Biography

Expertise includes: Metabolic regulation; pancreatic ß-cell metabolism and signal transduction; adipocyte metabolism and metabolic signal transduction; mitochondrial metabolism; cellular imaging of cations; reactive oxygen species; membrane potential and lipids; branched chain amino acid metabolism; inborn errors of mitochondrial metabolism; and acyl CoA regulation.

Other Positions

  • Zoltan Kohn Professor, Medicine, Boston University School of Medicine
  • Section Chief, Research Implementation, Medicine, Boston University School of Medicine
  • Professor, Biochemistry, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
  • Boston Medical Center

Education

  • University of Pennsylvania School of Medicine, PhD

Publications

  • Published on 12/1/2012

    Corkey BE. Diabetes: have we got it all wrong? Insulin hypersecretion and food additives: cause of obesity and diabetes? Diabetes Care. 2012 Dec; 35(12):2432-7. PMID: 23173132.

    Read at: PubMed
  • Published on 8/30/2012

    Corkey BE, Shirihai O. Metabolic master regulators: sharing information among multiple systems. Trends Endocrinol Metab. 2012 Dec; 23(12):594-601. PMID: 22939743.

    Read at: PubMed
  • Published on 1/17/2012

    Saadeh M, Ferrante TC, Kane A, Shirihai O, Corkey BE, Deeney JT. Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol. PLoS One. 2012; 7(1):e30200. PMID: 22272304.

    Read at: PubMed
  • Published on 1/1/2012

    Corkey BE. Banting lecture 2011: hyperinsulinemia: cause or consequence? Diabetes. 2012 Jan; 61(1):4-13. PMID: 22187369.

    Read at: PubMed
  • Published on 7/21/2011

    Haller JF, Krawczyk SA, Gostilovitch L, Corkey BE, Zoeller RA. Glucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1a to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic disease. Biochim Biophys Acta. 2011 Nov; 1812(11):1393-402. PMID: 21787864.

    Read at: PubMed
  • Published on 10/1/2010

    Zhong J, Krawczyk SA, Chaerkady R, Huang H, Goel R, Bader JS, Wong GW, Corkey BE, Pandey A. Temporal profiling of the secretome during adipogenesis in humans. J Proteome Res. 2010 Oct 1; 9(10):5228-38. PMID: 20707391.

    Read at: PubMed
  • Published on 12/24/2009

    Wang T, Si Y, Shirihai OS, Si H, Schultz V, Corkey RF, Hu L, Deeney JT, Guo W, Corkey BE. Respiration in adipocytes is inhibited by reactive oxygen species. Obesity (Silver Spring). 2010 Aug; 18(8):1493-502. PMID: 20035277.

    Read at: PubMed
  • Published on 7/30/2009

    Getty-Kaushik L, Richard AM, Deeney JT, Krawczyk S, Shirihai O, Corkey BE. The CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic islets. Obesity (Silver Spring). 2009 Oct; 17(10):1856-60. PMID: 19644453.

    Read at: PubMed
  • Published on 7/6/2009

    Molina AJ, Wikstrom JD, Stiles L, Las G, Mohamed H, Elorza A, Walzer G, Twig G, Katz S, Corkey BE, Shirihai OS. Mitochondrial networking protects beta-cells from nutrient-induced apoptosis. Diabetes. 2009 Oct; 58(10):2303-15. PMID: 19581419.

    Read at: PubMed
  • Published on 6/6/2009

    Pi J, Zhang Q, Fu J, Woods CG, Hou Y, Corkey BE, Collins S, Andersen ME. ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol Appl Pharmacol. 2010 Apr 1; 244(1):77-83. PMID: 19501608.

    Read at: PubMed

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