Barbara E. Corkey, PhD

Professor Emeritus, Medicine

Barbara Corkey
617.638.7091
650 Albany St Evans Biomed Research Ctr

Biography

Expertise includes: Metabolic regulation; pancreatic ß-cell metabolism and signal transduction; adipocyte metabolism and metabolic signal transduction; mitochondrial metabolism; cellular imaging of cations; reactive oxygen species; membrane potential and lipids; branched chain amino acid metabolism; inborn errors of mitochondrial metabolism; and acyl CoA regulation.

Other Positions

  • Zoltan Kohn Professor, Medicine, Boston University School of Medicine
  • Section Chief, Research Implementation, Medicine, Boston University School of Medicine
  • Professor, Biochemistry, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
  • Boston Medical Center

Education

  • University of Pennsylvania School of Medicine, PhD

Publications

  • Published on 8/19/2019

    Prentki M, Corkey BE, Madiraju SRM. Lipid-associated metabolic signalling networks in pancreatic beta cell function. Diabetologia. 2019 Aug 19. PMID: 31423551.

    Read at: PubMed
  • Published on 8/1/2019

    Nicholas DA, Proctor EA, Agrawal M, Belkina AC, Van Nostrand SC, Panneerseelan-Bharath L, Jones AR, Raval F, Ip BC, Zhu M, Cacicedo JM, Habib C, Sainz-Rueda N, Persky L, Sullivan PG, Corkey BE, Apovian CM, Kern PA, Lauffenburger DA, Nikolajczyk BS. Fatty Acid Metabolites Combine with Reduced ß Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes. Cell Metab. 2019 Sep 03; 30(3):447-461.e5. PMID: 31378464.

    Read at: PubMed
  • Published on 7/24/2019

    Thomas DD, Corkey BE, Istfan NW, Apovian CM. Hyperinsulinemia: An Early Indicator of Metabolic Dysfunction. J Endocr Soc. 2019 Sep 01; 3(9):1727-1747. PMID: 31528832.

    Read at: PubMed
  • Published on 9/13/2018

    Erion K, Corkey BE. ß-Cell Failure or ß-Cell Abuse? Front Endocrinol (Lausanne). 2018; 9:532. PMID: 30271382.

    Read at: PubMed
  • Published on 5/5/2018

    Pino EC, Zuo Y, Maciel De Olivera C, Mahalingaiah S, Keiser O, Moore LL, Li F, Vasan RS, Corkey BE, Kalesan B. Cohort profile: The MULTI sTUdy Diabetes rEsearch (MULTITUDE) consortium. BMJ Open. 2018 05 05; 8(5):e020640. PMID: 29730626.

    Read at: PubMed
  • Published on 4/3/2018

    Benador IY, Veliova M, Mahdaviani K, Petcherski A, Wikstrom JD, Assali EA, Acín-Pérez R, Shum M, Oliveira MF, Cinti S, Sztalryd C, Barshop WD, Wohlschlegel JA, Corkey BE, Liesa M, Shirihai OS. Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion. Cell Metab. 2018 04 03; 27(4):869-885.e6. PMID: 29617645.

    Read at: PubMed
  • Published on 12/4/2017

    Jones Iv AR, Coleman EL, Husni NR, Deeney JT, Raval F, Steenkamp D, Dooms H, Nikolajczyk BS, Corkey BE. Type 1 diabetes alters lipid handling and metabolism in human fibroblasts and peripheral blood mononuclear cells. PLoS One. 2017; 12(12):e0188474. PMID: 29206239.

    Read at: PubMed
  • Published on 10/2/2017

    Lamontagne J, Al-Mass A, Nolan CJ, Corkey BE, Madiraju SRM, Joly E, Prentki M. Identification of the signals for glucose-induced insulin secretion in INS1 (832/13) ß-cells using metformin-induced metabolic deceleration as a model. J Biol Chem. 2017 11 24; 292(47):19458-19468. PMID: 28972173.

    Read at: PubMed
  • Published on 6/16/2017

    Schwartz SS, Epstein S, Corkey BE, Grant SFA, Gavin Iii JR, Aguilar RB, Herman ME. A Unified Pathophysiological Construct of Diabetes and its Complications. Trends Endocrinol Metab. 2017 09; 28(9):645-655. PMID: 28629897.

    Read at: PubMed
  • Published on 6/1/2017

    Erion KA, Corkey BE. Hyperinsulinemia: a Cause of Obesity? Curr Obes Rep. 2017 Jun; 6(2):178-186. PMID: 28466412.

    Read at: PubMed

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