Bang-bon Bon Koo, PhD
Associate Professor, Anatomy & Neurobiology
Biography
Dr. Koo’s research interests span the areas of neuroimaging, particularly the development of multi-modal magnetic resonance imaging (MRI) and analysis methods. Neuroimaging commonly aims to identify difference between healthy and unhealthy brains in a quantitative way. However, due to the complexity of the human brain, it is extremely difficult to analyze early stage or slow disease progressions from visually inspecting the image. Dr. Koo’s work focuses on developing novel imaging protocols and mapping methods with better sensitivities on monitoring neurological and functional changes in the brain. Dr. Koo also serves as an imaging core director at National Emerging Infectious Disease Laboratories (NEIDL). The goal is to develop multimodal imaging protocol that allows in-vivo monitoring on different stages of tissue inflammatory/immune responses.
Other Positions
- Faculty, National Emerging Infectious Disease Lab, Boston University
- Graduate Faculty (Primary Mentor of Grad Students), Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Education
- Hanyang University, PhD
- Hanyang University, MS
- Hanyang University, BS
Classes Taught
- AN718
- BI 451
- IM655
- IM680
- NE391
Publications
- Published on 9/30/2024
Cheng CH, Guan Y, Chiplunkar VP, Mortazavi F, Medalla ML, Sullivan K, O'Callaghan JP, Koo BB, Kelly KA, Michalovicz LT. Nerve agent exposure and physiological stress alter brain microstructure and immune profiles after inflammatory challenge in a long-term rat model of Gulf War Illness. Brain Behav Immun Health. 2024 Dec; 42:100878. PMID: 39430882.
Read at: PubMed - Published on 5/1/2024
Krengel M, Keating D, Chao L, Dugas J, Koo B, Heeren T, Quinn E, Toomey R, Steele L, Klimas N, Samonte F, Abdullah L, Sullivan K. Characterizing 1991 Gulf War women veterans from the Boston Biorepository and Integrative Network for Gulf War Illness: Demographics, exposures, neuroimaging and cognitive outcomes. Clin Neuropsychol. 2024 Aug; 38(6):1454-1467. PMID: 38692856.
Read at: PubMed - Published on 2/13/2024
Gordon S, Lee JS, Scott TM, Bhupathiraju S, Ordovas J, Kelly RS, Bhadelia R, Koo BB, Bigornia S, Tucker KL, Palacios N. Metabolites and MRI-Derived Markers of AD/ADRD Risk in a Puerto Rican Cohort. Res Sq. 2024 Feb 13. PMID: 38410484.
Read at: PubMed - Published on 1/22/2024
Chao LL, Sullivan K, Krengel MH, Killiany RJ, Steele L, Klimas NG, Koo BB. The prevalence of mild cognitive impairment in Gulf War veterans: a follow-up study. Front Neurosci. 2023; 17:1301066. PMID: 38318196.
Read at: PubMed - Published on 12/12/2023
Guan Y, Cheng CH, Bellomo LI, Narain S, Bigornia SJ, Garelnabi MO, Scott T, Ordovás JM, Tucker KL, Bhadelia R, Koo BB. Corrigendum: APOE4 allele-specific associations between diet, multimodal biomarkers, and cognition among Puerto Rican adults in Massachusetts. Front Aging Neurosci. 2023; 15:1343591. PMID: 38149171.
Read at: PubMed - Published on 11/15/2023
Guan Y, Cheng CH, Bellomo LI, Narain S, Bigornia SJ, Garelnabi MO, Scott T, Ordovás JM, Tucker KL, Bhadelia R, Koo BB. APOE4 allele-specific associations between diet, multimodal biomarkers, and cognition among Puerto Rican adults in Massachusetts. Front Aging Neurosci. 2023; 15:1285333. PMID: 38035273.
Read at: PubMed - Published on 11/1/2023
He S, Guan Y, Cheng CH, Moore TL, Luebke JI, Killiany RJ, Rosene DL, Koo BB, Ou Y. Human-to-monkey transfer learning identifies the frontal white matter as a key determinant for predicting monkey brain age. Front Aging Neurosci. 2023; 15:1249415. PMID: 38020785.
Read at: PubMed - Published on 1/31/2023
Naeser MA, Martin PI, Ho MD, Krengel MH, Bogdanova Y, Knight JA, Hamblin MR, Fedoruk AE, Poole LG, Cheng C, Koo B. Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy. J Alzheimers Dis Rep. 2023; 7(1):77-105. PMID: 36777329.
Read at: PubMed - Published on 1/17/2023
Koo BB, Guan Y. Author Response: Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. 2023 Jan 17; 100(3):164-165. PMID: 36646472.
Read at: PubMed - Published on 3/30/2022
Guan Y, Ebrahimzadeh SA, Cheng CH, Chen W, Leung T, Bigornia S, Palacios N, Garelnabi MO, Scott T, Bhadelia R, Tucker KL, Koo BB. Association of Diabetes and Hypertension With Brain Structural Integrity and Cognition in the Boston Puerto Rican Health Study Cohort. Neurology. 2022 Apr 12; 98(15):e1534-e1544. PMID: 35354581.
Read at: PubMed
View 48 more publications: View full profile at BUMC