Aruna Pradhan, MD

Adjunct Assistant Professor, Medicine

Aruna Pradhan

Biography

An associate epidemiologist, cardiologist, and Assistant Professor of Medicine at Harvard Medical School, Dr. Pradhan joined CIRT in 2005. She has joint appointments in the Division of Preventive Medicine at the Brigham and Women’s Hospital and Cardiovascular Medicine Division at the Veteran’s Administration Hospital, West Roxbury Campus. Her research interests span the related areas of inflammation, diabetes, and peripheral artery disease. Her early work demonstrated a strong link between subclinical inflammation and the development of diabetes. She continued this line of research as the Principal Investigator of the LANCET clinical trial which studied insulin therapy as a strategy to reduce inflammation among patients with diabetes during the initial stage of this disease. Other research activities pertain to the role of adipokines and other biologic markers having combined metabolic and inflammatory functions in the pathogenesis of diabetes and its vascular complications. As a recipient of a career development award from the National Heart, Lung, and Blood Institute to study risk factors for peripheral artery disease, Dr. Pradhan is also keenly interested in evaluating risk factors and underlying mechanisms that distinguish individuals at high risk for future coronary artery disease as compared to lower extremity artery disease. Dr. Pradhan is also a recipient of NIH funding to evaluate mechanisms of statin-associated diabetes in the JUPITER trial.

Dr. Pradhan completed her cardiovascular medicine fellowship at the Brigham and Women’s Hospital and continues her clinical activities as an echocardiographer and clinical cardiologist at the VA Boston Healthcare System, West Roxbury Campus.

Other Positions

  • VA Boston Healthcare System

Education

  • Georgetown University School of Medicine, MD
  • Harvard School of Public Health, MSc
  • Johns Hopkins University School of Public Health, MPH
  • Georgetown University, BS

Publications

  • Published on 6/18/2022

    Bartoli-Leonard F, Turner ME, Zimmer J, Chapurlat R, Pham T, Aikawa M, Pradhan AD, Szulc P, Aikawa E. Elevated lipoprotein(a) as a predictor for coronary events in older men. J Lipid Res. 2022 Jun 18; 63(8):100242. PMID: 35724702.

    Read at: PubMed
  • Published on 7/21/2021

    Pradhan AD. Time to commence or time out for colchicine in secondary prevention of cardiovascular disease? Eur Heart J. 2021 07 21; 42(28):2776-2779. PMID: 33824963.

    Read at: PubMed
  • Published on 6/18/2021

    Levin MG, Zuber V, Walker VM, Klarin D, Lynch J, Malik R, Aday AW, Bottolo L, Pradhan AD, Dichgans M, Chang KM, Rader DJ, Tsao PS, Voight BF, Gill D, Burgess S, Damrauer SM. Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease. Circulation. 2021 08 03; 144(5):353-364. PMID: 34139859.

    Read at: PubMed
  • Published on 5/27/2021

    Aday AW, Duran EK, Van Denburgh M, Kim E, Christen WG, Manson JE, Ridker PM, Pradhan AD. Homocysteine Is Associated With Future Venous Thromboembolism in 2 Prospective Cohorts of Women. Arterioscler Thromb Vasc Biol. 2021 07; 41(7):2215-2224. PMID: 34039021.

    Read at: PubMed
  • Published on 1/8/2021

    Duran EK, Pradhan AD. Triglyceride-Rich Lipoprotein Remnants and Cardiovascular Disease. Clin Chem. 2021 01 08; 67(1):183-196. PMID: 33409533.

    Read at: PubMed
  • Published on 5/5/2020

    Duran EK, Aday AW, Cook NR, Buring JE, Ridker PM, Pradhan AD. Triglyceride-Rich Lipoprotein Cholesterol, Small Dense LDL Cholesterol, and Incident Cardiovascular Disease. J Am Coll Cardiol. 2020 05 05; 75(17):2122-2135. PMID: 32354380.

    Read at: PubMed
  • Published on 4/13/2020

    Pradhan AD, Aday AW, Beckman JA. The Big MAC Attack on Peripheral Artery Disease. Circulation. 2020 04 14; 141(15):1211-1213. PMID: 32282252.

    Read at: PubMed
  • Published on 2/18/2020

    Solomon DH, Glynn RJ, Karlson EW, Lu F, Corrigan C, Colls J, Xu C, MacFadyen J, Barbhaiya M, Berliner N, Dellaripa PF, Everett BM, Pradhan AD, Hammond SP, Murray M, Rao DA, Ritter SY, Rutherford A, Sparks JA, Stratton J, Suh DH, Tedeschi SK, Vanni KMM, Paynter NP, Ridker PM. Adverse Effects of Low-Dose Methotrexate: A Randomized Trial. Ann Intern Med. 2020 03 17; 172(6):369-380. PMID: 32066146.

    Read at: PubMed
  • Published on 9/5/2019

    Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, Boehnke M, Borja JB, Bork-Jensen J, Broer L, Chasman DI, Chen YI, Chirstofidou P, Demirkan A, van Duijn CM, Feitosa MF, Garcia ME, Graff M, Grallert H, Grarup N, Guo X, Haesser J, Hansen T, Harris TB, Highland HM, Hong J, Ikram MA, Ingelsson E, Jackson R, Jousilahti P, Kähönen M, Kizer JR, Kovacs P, Kriebel J, Laakso M, Lange LA, Lehtimäki T, Li J, Li-Gao R, Lind L, Luan J, Lyytikäinen LP, MacGregor S, Mackey DA, Mahajan A, Mangino M, Männistö S, McCarthy MI, McKnight B, Medina-Gomez C, Meigs JB, Molnos S, Mook-Kanamori D, Morris AP, de Mutsert R, Nalls MA, Nedeljkovic I, North KE, Pennell CE, Pradhan AD, Province MA, Raitakari OT, Raulerson CK, Reiner AP, Ridker PM, Ripatti S, Roberston N, Rotter JI, Salomaa V, Sandoval-Zárate AA, Sitlani CM, Spector TD, Strauch K, Stumvoll M, Taylor KD, Thuesen B, Tönjes A, Uitterlinden AG, Venturini C, Walker M, Wang CA, Wang S, Wareham NJ, Willems SM, Willems van Dijk K, Wilson JG, Wu Y, Yao J, Young KL, Langenberg C, Frayling TM, Kilpeläinen TO, Lindgren CM, Loos RJF, Mohlke KL. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. Am J Hum Genet. 2019 Sep 05; 105(3):670-671. PMID: 31491410.

    Read at: PubMed
  • Published on 7/19/2019

    Duran EK, Cook NR, Bobadilla M, Kim E, Manson JE, Buring JE, Ridker PM, Pradhan AD. Plasma Placental Growth Factor Concentrations Are Elevated Well in Advance of Type 2 Diabetes Mellitus Onset: Prospective Data From the WHS. J Am Heart Assoc. 2019 08 06; 8(15):e012790. PMID: 31322059.

    Read at: PubMed

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