Anna Belkina, MD, PhD

Assistant Professor, Pathology & Laboratory Medicine

Anna Belkina
617.358.7732
650 Albany St Evans Biomed Research Ctr

Biography

Dr. Belkina received her M.D. from Russian State Medical University and her Ph.D. in Molecular Medicine from BU School of Medicine investigating the epigenetic regulation of inflammatory responses driven by bromodomain proteins. Her breadth of knowledge of flow cytometric applications includes the development of intra- and extra-cellular staining protocols and panels for use in a wide variety of applications, including immunophenotyping of mouse and human cells, apoptosis assays, cell cycle profiling and stem cell isolation. At the FCCF, Dr. Belkina assists our users with experimental design, panel development, data analysis and many other facets of flow cytometry, and is a fully proficient BD FACSARIA operator. She also trains new users and is responsible for instrument maintenance.
Anna’s research is focused on the intersection of immunology and computational biology, for her current research efforts include investigating the immune landscape of chronic inflammatory diseases and developing computational techniques to assess high-parameter single cell cytometry data. Anna is an active member of ISAC (International Society for the Advancement of Cytometry) and has been named 2015-2019 ISAC SRL Emerging Leader.

Publications

  • Published on 12/5/2018

    Belkina AC, Starchenko A, Drake KA, Proctor EA, Pihl RMF, Olson A, Lauffenburger DA, Lin N, Snyder-Cappione JE. Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging. Front Immunol. 2018; 9:2783. PMID: 30568654.

    Read at: PubMed
  • Published on 8/27/2018

    Akiyama H, Miller CM, Ettinger CR, Belkina AC, Snyder-Cappione JE, Gummuluru S. HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction. Nat Commun. 2018 08 27; 9(1):3450. PMID: 30150664.

    Read at: PubMed
  • Published on 7/20/2018

    Kartha VK, Alamoud KA, Sadykov K, Nguyen BC, Laroche F, Feng H, Lee J, Pai SI, Varelas X, Egloff AM, Snyder-Cappione JE, Belkina AC, Bais MV, Monti S, Kukuruzinska MA. Functional and genomic analyses reveal therapeutic potential of targeting ß-catenin/CBP activity in head and neck cancer. Genome Med. 2018 07 20; 10(1):54. PMID: 30029671.

    Read at: PubMed
  • Published on 3/7/2018

    Fleury M, Belkina AC, Proctor EA, Zammitti C, Simms RW, Lauffenburger DA, Snyder-Cappione JE, Lafyatis R, Dooms H. Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis. Arthritis Rheumatol. 2018 Apr; 70(4):566-577. PMID: 29245183.

    Read at: PubMed
  • Published on 9/18/2017

    Woolf N, Pearson BE, Bondzie PA, Meyer RD, Lavaei M, Belkina AC, Chitalia V, Rahimi N. Targeting tumor multicellular aggregation through IGPR-1 inhibits colon cancer growth and improves chemotherapy. Oncogenesis. 2017 Sep 18; 6(9):e378. PMID: 28920928.

    Read at: PubMed
  • Published on 12/30/2016

    Lentucci C, Belkina AC, Cederquist CT, Chan M, Johnson HE, Prasad S, Lopacinski A, Nikolajczyk BS, Monti S, Snyder-Cappione J, Tanasa B, Cardamone MD, Perissi V. Inhibition of Ubc13-mediated Ubiquitination by GPS2 Regulates Multiple Stages of B Cell Development. J Biol Chem. 2017 Feb 17; 292(7):2754-2772. PMID: 28039360.

    Read at: PubMed
  • Published on 10/5/2016

    Belkina AC, Snyder-Cappione JE. OMIP-037: 16-color panel to measure inhibitory receptor signatures from multiple human immune cell subsets. Cytometry A. 2017 02; 91(2):175-179. PMID: 27706900.

    Read at: PubMed
  • Published on 9/1/2016

    Kamata H, Yamamoto K, Wasserman GA, Zabinski MC, Yuen CK, Lung WY, Gower AC, Belkina AC, Ramirez MI, Deng JC, Quinton LJ, Jones MR, Mizgerd JP. Epithelial Cell-Derived Secreted and Transmembrane 1a Signals to Activated Neutrophils during Pneumococcal Pneumonia. Am J Respir Cell Mol Biol. 2016 Sep; 55(3):407-18. PMID: 27064756.

    Read at: PubMed
  • Published on 7/21/2016

    Andrieu G, Belkina AC, Denis GV. Clinical trials for BET inhibitors run ahead of the science. Drug Discov Today Technol. 2016 Mar; 19:45-50. PMID: 27769357.

    Read at: PubMed
  • Published on 3/23/2016

    Deeney JT, Belkina AC, Shirihai OS, Corkey BE, Denis GV. BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic ß-Cell. PLoS One. 2016; 11(3):e0151329. PMID: 27008626.

    Read at: PubMed

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