Allen A. Mitchell, MD

Professor, Epidemiology

Allen Mitchell
(617) 206-6210
72 E. Concord St Instructional (L)

Biography

Allen A. Mitchell is Professor of Public Health (Epidemiology) and Professor of Pediatrics at the Boston University Schools of Public Health and Medicine. He obtained his BA degree from Washington University in St. Louis in 1966 and his M.D. from Tufts University School of Medicine in Boston in 1970.

After pediatric residency training at the Boston Floating Hospital for Infants and Children (Tufts-New England Medical Center), he joined the Boston Collaborative Drug Surveillance Program where, among other activities, he worked with Drs. Slone, Shapiro, and Heinonen in the analysis of Collaborative Perinatal Project data on birth defects and drugs in pregnancy.

In 1973-75 he was a fellow in pediatric clinical pharmacology at Children’s Hospital in Boston (jointly with the Center for the Evaluation of Clinical Procedures at the Harvard School of Public Health), during which time he established the Pediatric Drug Surveillance (“PeDS”) Program, an intensive drug surveillance effort focused on the frequency of medication use and adverse effects among hospitalized children. In 1975 he joined Drs. Slone and Shapiro at the newly-created Drug Epidemiology Unit (now Slone Epidemiology Center–SEC) at Boston University, where he continued to direct the PeDS Program.

Following his interest in both pharmacoepidemiology and birth defects, Dr. Mitchell in 1975 applied the concept of case-control surveillance to the study of teratogenesis, and initiated the SEC Birth Defects Study (BDS) which continues to this time, having collected data on prenatal exposures for over 36,000 malformed infants (and controls) identified at over 90 hospitals and state birth defects registries in the regions surrounding Boston, Philadelphia, Toronto, and San Diego. The BDS is now one of two data collection components collaborating with the American Academy of Allergy, Asthma, and Immunology in a national systematic surveillance effort (Vaccines and Medication in Pregnancy Safety Surveillance—“VAMPSS”) designed to evaluate the risks and safety of the wide range of medications taken by pregnant women. Dr. Mitchell also designed and directed a practitioner-based trial of 84,000 children to assess the safety of pediatric ibuprofen, a network that continues to conduct clinically-relevant office-based research, directed epidemiologic efforts to evaluate pregnancy prevention efforts as part of risk management programs associated with isotretinoin (Accutane and others) and thalidomide (Thalomid), and designed the Slone Survey.

Dr. Mitchell is the author of numerous publications in the fields of pediatric and birth defects pharmacoepidemiology and serves on many editorial boards and advisory committees.

Other Positions

  • Professor, General Pediatrics, Pediatrics, Boston University School of Medicine

Education

  • Tufts University School of Medicine, MD
  • Washington University in St. Louis, BA

Publications

  • Published on 10/20/2017

    Kerr S, Van Bennekom CM, Liang JL, Mitchell AA. Tdap Vaccination Coverage During Pregnancy - Selected Sites, United States, 2006-2015. MMWR Morb Mortal Wkly Rep. 2017 Oct 20; 66(41):1105-1108. PMID: 29049273.

    Read at: PubMed
  • Published on 9/25/2017

    Chambers CD, Xu R, Mitchell AA. Commentary on: "Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010-11 and 2011-12". Vaccine. 2017 Sep 25; 35(40):5323-5324. PMID: 28917296.

    Read at: PubMed
  • Published on 12/9/2016

    Kerr S, Van Bennekom CM, Mitchell AA. Influenza Vaccination Coverage During Pregnancy - Selected Sites, United States, 2005-06 Through 2013-14 Influenza Vaccine Seasons. MMWR Morb Mortal Wkly Rep. 2016 Dec 09; 65(48):1370-1373. PMID: 27932781.

    Read at: PubMed
  • Published on 7/21/2016

    Louik C, Kerr S, Van Bennekom CM, Chambers C, Jones KL, Schatz M, Mitchell AA. Safety of the 2011-12, 2012-13, and 2013-14 seasonal influenza vaccines in pregnancy: Preterm delivery and specific malformations, a study from the case-control arm of VAMPSS. Vaccine. 2016 Aug 17; 34(37):4450-9. PMID: 27452865.

    Read at: PubMed
  • Published on 7/20/2016

    Chambers CD, Johnson DL, Xu R, Luo YJ, Louik C, Mitchell AA, Schatz M, Jones KL. Safety of the 2010-11, 2011-12, 2012-13, and 2013-14 seasonal influenza vaccines in pregnancy: Birth defects, spontaneous abortion, preterm delivery, and small for gestational age infants, a study from the cohort arm of VAMPSS. Vaccine. 2016 Aug 17; 34(37):4443-9. PMID: 27449682.

    Read at: PubMed
  • Published on 5/24/2016

    Darling AM, Mitchell AA, Werler MM. Preconceptional Iron Intake and Gestational Diabetes Mellitus. Int J Environ Res Public Health. 2016 May 24; 13(6). PMID: 27231921.

    Read at: PubMed
  • Published on 5/24/2016

    Mitchell AA. Research challenges for drug-induced birth defects. Clin Pharmacol Ther. 2016 Jul; 100(1):26-8. PMID: 27037730.

    Read at: PubMed
  • Published on 5/8/2016

    Benedum CM, Yazdy MM, Parker SE, Mitchell AA, Werler MM. Association of Clomiphene and Assisted Reproductive Technologies With the Risk of Neural Tube Defects. Am J Epidemiol. 2016 Jun 01; 183(11):977-87. PMID: 27188944.

    Read at: PubMed
  • Published on 10/9/2015

    Simeone RM, Feldkamp ML, Reefhuis J, Mitchell AA, Gilboa SM, Honein MA, Iskander J. CDC Grand Rounds: Understanding the Causes of Major Birth Defects - Steps to Prevention. MMWR Morb Mortal Wkly Rep. 2015 Oct 9; 64(39):1104-7. PMID: 26447345.

    Read at: PubMed
  • Published on 9/29/2015

    Benedum CM, Yazdy MM, Mitchell AA, Werler MM. Impact of Periconceptional Use of Nitrosatable Drugs on the Risk of Neural Tube Defects. Am J Epidemiol. 2015 Oct 15; 182(8):675-84. PMID: 26424074.

    Read at: PubMed

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