Alice K. Jacobs, MD

Professor, Medicine

Alice Jacobs
88 E. Newton St Newton Pavilion


Alice K. Jacobs, MD, FACC, FAHA, MSCAI is a Professor of Medicine at Boston University School of Medicine and served as the Director of the Cardiac Catheterization Laboratories and Interventional Cardiology for 20 years until 2011. She is currently Vice Chair for Clinical Affairs in the Department of Medicine at Boston University Medical Center and maintains an active clinical practice. Dr. Jacobs has led the American Heart Association’s Mission: Lifeline, a community-based, national initiative to develop systems of care for ST-segment elevation myocardial infarction (STEMI) patients and to increase the number of patients with timely access to primary percutaneous coronary intervention. Mission: Lifeline has now expanded to include Out-of-Hospital Cardiac Arrest and Stroke systems of care. Dr. Jacobs served as president of the American Heart Association in 2004-05 and as president of the Association of University Cardiologists in 2011. She is a past chair of the ACC/AHA Task Force on Practice Guidelines. During her tenure, the guidelines process and methodology evolved to include formal systematic evidence reviews, inclusion of patient representatives and lay members on guideline committees, incorporation of an Evidence Grading Tool, and further enhancements to the Class of Recommendation/Level of Evidence schema. Dr. Jacobs is a prior member of CMS MEDCAC and the IOM Committee on Social Security Cardiovascular Disability. Currently, she is the immediate past-chair of the American Board of Internal Medicine Interventional Cardiology Self-Assessment Test Committee, a member of NHLBI Cardiothoracic Surgical Network Protocol Review Committee and a member of the New York State Cardiac Advisory Committee. Her major research interest is in coronary revascularization strategies and sex-based difference in ischemic heart disease.

Expertise includes: Interventional Cardiology; Coronary revascularization; Sex-based differences in cardiovascular disease.

Other Positions

  • Member, Whitaker Cardiovascular Institute, Boston University
  • Member, Evans Center for Interdisciplinary Biomedical Research, Boston University


  • Saint Louis University, MD
  • State University of New York at Buffalo, BA


  • Published on 10/13/2021

    Jacobs AK, Ali MJ, Best PJ, Bieniarz MC, Bufalino VJ, French WJ, Henry TD, Hollowell L, Jauch EC, Kurz MC, Levy M, Patel P, Spier T, Stone RH, Tataris KL, Thomas RJ, Zègre-Hemsey JK. Systems of Care for ST-Segment-Elevation Myocardial Infarction: A Policy Statement From the American Heart Association. Circulation. 2021 Oct 13; CIR0000000000001025. PMID: 34641735.

    Read at: PubMed
  • Published on 10/2/2021

    Hannan EL, Wu Y, Cozzens K, Friedrich M, Walford G, Ling FSK, Venditti FJ, Jacobs AK, Tamis-Holland J, Berger PB, King SB. The Association of Socio-Economic Factors with Percutaneous Coronary Intervention Outcomes. Can J Cardiol. 2021 Oct 02. PMID: 34610383.

    Read at: PubMed
  • Published on 3/28/2021

    Hannan EL, Wu YF, Cozzens K, Tamis-Holland J, Ling FSK, Jacobs AK, Venditti FJ, Berger PB, Walford G, King Iii SB. Hybrid coronary revascularization vs. percutaneous coronary interventions for multivessel coronary artery disease. J Geriatr Cardiol. 2021 Mar 28; 18(3):159-167. PMID: 33907545.

    Read at: PubMed
  • Published on 12/8/2020

    Hannan EL, Wu Y, Cozzens K, Friedrich M, Tamis-Holland J, Jacobs AK, Ling FSK, King SB, Venditti FJ, Walford G, Berger PB, Kirtane AJ, Kamran M. Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction Before and During COVID in New York. Am J Cardiol. 2021 03 01; 142:25-34. PMID: 33301770.

    Read at: PubMed
  • Published on 11/7/2020

    Shahandeh N, Dai X, Jaski B, Dave R, Jacobs A, Denktas A, Levine G, Markovic D, Smith SC, Press MC. Mortality differences among patients with in-hospital ST-elevation myocardial infarction. Clin Cardiol. 2020 Dec; 43(12):1555-1561. PMID: 33159461.

    Read at: PubMed
  • Published on 7/1/2020

    Mendirichaga R, Jacobs AK. Sex Differences in Ischemic Heart Disease-the Paradox Persists. JAMA Cardiol. 2020 07 01; 5(7):754-756. PMID: 32227138.

    Read at: PubMed
  • Published on 4/22/2020

    Al-Lamee R, Jacobs AK. ISCHEMIA Trial: Was It Worth the Wait? Circulation. 2020 08 11; 142(6):517-519. PMID: 32316761.

    Read at: PubMed
  • Published on 1/20/2020

    Kontos MC, Gunderson MR, Zegre-Hemsey JK, Lange DC, French WJ, Henry TD, McCarthy JJ, Corbett C, Jacobs AK, Jollis JG, Manoukian SV, Suter RE, Travis DT, Garvey JL. Prehospital Activation of Hospital Resources (PreAct) ST-Segment-Elevation Myocardial Infarction (STEMI): A Standardized Approach to Prehospital Activation and Direct to the Catheterization Laboratory for STEMI Recommendations From the American Heart Association's Mission: Lifeline Program. J Am Heart Assoc. 2020 01 21; 9(2):e011963. PMID: 31957530.

    Read at: PubMed
  • Published on 10/23/2019

    Hannan EL, Zhong Y, Ling FSK, Tamis-Holland J, Berger PB, Jacobs AK, Walford G, Venditti FJ, King SB. Assessment of repeat target lesion percutaneous coronary intervention as a quality measure for public reporting and general quality assessment for PCIs. Catheter Cardiovasc Interv. 2020 10 01; 96(4):731-740. PMID: 31642597.

    Read at: PubMed
  • Published on 5/1/2019

    Rymer JA, Kaltenbach LA, Kochar A, Hess CN, Gilchrist IC, Messenger JC, Harrington RA, Jolly SS, Jacobs AK, Abbott JD, Wojdyla DM, Krucoff MW, Rao SV. Comparison of Rates of Bleeding and Vascular Complications Before, During, and After Trial Enrollment in the SAFE-PCI Trial for Women. Circ Cardiovasc Interv. 2019 05; 12(5):e007086. PMID: 31014090.

    Read at: PubMed

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