Employment Opportunities
Postdoctoral position in Vascular Biology
The Laboratory of Dr Francesca Seta at Boston University Chobanian and Avedisian School of Medicine, Vascular Biology Section is seeking to fill a Postdoctoral Research Scientist position in the area of vascular biology.
Dr Seta’s laboratory investigates the basic mechanisms of arterial stiffening and aortic aneurysms/dissections, with a focus on the biology of the vascular smooth muscle. The successful applicant will develop a recently NHLBI-funded project to examine the role of the protein sirtuin-1 in the regulation of vascular smooth muscle phenotype and arterial function in models of aortic aneurysm. Current studies are also examining potential therapeutic targets for aortic aneurysms/dissection. The laboratory employs state-of-the art approaches such as high-resolution ultrasound echocardiography, micro computed tomography, radiotelemetry, high-fidelity pressure catheters and pressurized myography to assess vascular function in vivo and ex vivo. This is an excellent opportunity for a highly motivated and enthusiastic individual to learn vascular surgical and imaging skills, if desired.
Laboratory personnel have access to state-of-the-art research instrumentation through the Boston University Analytical, Metabolic, Imaging, Spectral Cytometry, RNA Sequencing, Spatial Biology, CryoEM Cores (http://www.bumc.bu.edu/busm/research/cores/). The Vascular Biology Section is part of the Department of Medicine and the Whitaker Cardiovascular Institute (https://www.bumc.bu.edu/busm-wci/), a world leading institution in the field of cardiovascular research with an highly interdisciplinary and collaborative environment and close interaction between clinicians and basic scientists.
Requirements and Qualifications:
- PhD or MD degree in biological or biomedical sciences, with at least 1 first-author original research publication in a leading peer-reviewed journal.
- Expertise in vascular biology and molecular biology (qRT-PCR, Western Blotting, cloning, adenovirus production, ChIP assay, immunoprecipitation, immunohistochemistry/immunofluorescence), ChIP-Seq/RNA-Seq, flow cytometry, etc) is highly desirable.
- The ideal candidate has previous training and extensive working experience in one or more of the following areas: (1) animal husbandry and handling; (2) mechanistic studies in animal models (possibly obesity/metabolic syndrome, hypertension and/or aortic aneurysm); (3) proficiency with vascular smooth muscle cells and vessel dissection; (4) vascular surgery and echocardiography; (5) epigenetic analysis and transcriptional regulation; (6) flow cytometry.
- Bioinformatics skills to analyze large datasets are definitely a plus.
- Excellent communication skills, strong motivation, high level of integrity and ethical standard, ability to advance a project productively and work independently are required.
Competitive salary will be commensurate with relevant experience and based on NIH guidelines (rang2 $ 67,500-72,000). Eligible Postdoctoral Research Scientists qualify for Boston University-based benefits including pension plan, health and life insurance, and tuition discount. Opportunity for professional development is offered through the Office of Professional Development and Postdoctoral Affairs.
Interested candidates should submit a curriculum vitae and contact details of 3 references to Dr Francesca Seta at setaf@bu.edu. Applications will be considered until the position is filled. Boston University is an equal opportunity employer: minorities, women, veterans and individuals with disabilities are encouraged to apply.
Postdoctoral Associate Position: