Department of Pathology & Laboratory Medicine: New News Winter 2020-21

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March 24th, 2021

Department of Pathology & Laboratory Medicine:

New News Winter 2020-21

Announcements

  • Dennis Jones, PhD, Assistant Professor of Pathology & Laboratory Medicine, has been named the 2021 Dahod Assistant Professor; he will collaborate with Dr. Andrew Emili to identify immunosuppressive molecules contained in cancer cell derived-exosomes and investigate their impact on T cells, a type of immune cell that can recognize and kill breast cancer cells. Blocking such immunosuppressive mechanisms may promote the anti-tumor activity of T cells, thus enhancing their ability to eliminate breast cancers
  • Dr. Jones also received a Metavivior Early Career Investigator Award to study “Targeting breast cancer plasticity and immunosuppression in metastatic lymph nodes”
    • Metavivor Research and Support Inc., is a non-profit organization dedicated to funding research for stage IV metastatic breast cancer (MBC) that announced 23 new grant awards totaling $3,650,000.  These research grants will enhance the understanding of metastatic breast cancer, help improve current treatments and develop greatly needed therapeutic options to combat this complicated disease. Since its founding in 2009, METAvivor has put 100% of donations into its peer-reviewed research grant program. https://www.metavivor.org/blog/metavivor-announces-grant-awards-for-metastatic-breast-cancer-research/
  • Daniel Remick, M.D. has been recruited to serve on an NIH study section to review applications for the NCI’s Loan Repayment Program. This program encourages health professionals to participate in research by paying a portion of their student loans
  • USCAP Virtual Annual Meeting: March 13-18, 2021
    • Nola Tochukwu Ihejirika, Masters student in Dr. Joel Henderson’s Lab has a poster presentation at the 2021 USCAP Annual Meeting! The title of her presentation is “Definitive Characterization of Protein Reabsorption Granules vs. Punctate IgG Immunoreactivity in Primary Podocytopathies” Authors: Junbo Chen, MA, Hui Chen, Morgan Thompson, MA and Dr. Joel Henderson
    • Junbo Chen, MA will present: “Punctate Visceral Epithelial IgG Immunoreactivity Associated with Podocytopathies Exhibits Heterogeneous Oligoclonality and Absence of Complement” Authors: Junbo Chen, Gabriel Lerner, Hui A Chen, Astrid Weins, Joel M. Henderson
    • Charitha Vadlamudi, MD, Pathology Resident, will present “Amyloid Typing of Formalin Fixed Paraffin Embedded Tissue by Immunohistochemistry” Authors: Charitha Vadlamudi1, Emily Aniskovich1, Hui Chen1, Haili Cui2, Lawreen H Connors2, Vaishali Sanchorawala2, Eric J Burks
    • Manisha Cole, Masters student in Dr. Yachana Kataria’s Lab will present, “Seroprevalence of SARS-CoV-2 IgG Antibodies in Health Care Workers at an Academic Medical Center in Boston, Massachusetts” Authors: Manisha Cole1,2, Yachana Kataria1,2, Elizabeth Duffy2, Kyle de la Cena1,2, Elissa Perkins, Tara Bouton, Martha Werler, Cassandra Pierre, Karen Jacobson, Elizabeth Ragan, Chris Andry1,2
  • Also USCAP Related:
    • The Association of Indian Pathologists in North America (AIPNA) has awarded Best Abstract Competition USCAP-Second Prize to:
      • Charitha Vadlamudi, Emily Aniskovich, Hui Chen, Haili Cui, Lawreen H Connors, Vaishali Sanchorawala, Eric J Burks.  Amyloid Typing of Formalin Fixed Paraffin Embedded Tissue by Immunohistochemistry. USCAP 2021 Annual Meeting, Poster
    • Martin Steinbuck, Pathology BU PhD Graduate recent publication: https://advances.sciencemag.org/content/7/6/eabe5819/tab-article-info
    • Rachel Flynn is a recipient of a 2021 Shipley Pilot Grant
  • Welcome to:
    • Brian Moore, MD, MEd, new Faculty Member
    • Introducing our new incoming Residents for the 2021-22 academic year:
    • Isa M. Jacoba, MD
    • Boston, MA
    • University of the East/Ramon Magsasay Memorial Medical Center, Quezon City, Philippines
    • Soo Hyun Lee MD, PhD, MS
    • Houston, TX
    • Ewha Womans University School of Medicine, Seoul, South Korea
    • Ramya Narasimhan, MBBS
    • Rochester, MN
    • Kasturba Medical College, Manipal, India
    • Adeyemi Sofoluwe, MD, MBA
    • Boston, MA
    • University of Health Sciences Antigua School of Medicine, Piccadilly, Antigua & Barbuda
  • Thor D. Stein, MD, PhD has been awarded the Spivack Pilot Fund Award

 

 

 

Publications. Published:

  • Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A.; “Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2” Mol Cell. 2020 Dec 17;80(6):1104-1122.e9. doi: 10.1016/j.molcel.2020.11.028
  • Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A.; “Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2” Mol Cell. 2021 Jan 7;81(1):212. doi: 10.1016/j.molcel.2020.12.028
  • Kalantzakos TJ, Sullivan TB, Sebel LE, Canes D, Burks EJ, Moinzadeh A, Rieger-Christ KM; “MicroRNAs MiR-15a and MiR-26a cooperatively regulate O-GlcNAc-transferase to control proliferation in clear cell renal cell carcinoma” Cancer Biomark. 2020 Dec 3. doi: 10.3233/CBM-200553

       Publications. Accepted:

  • JeffersonChena, Pedro ViniciusStaziakia, HanqiaoZhengb, Eric J.Burks, SaraMeibomc, Virginia R.Litled, Hristina N.Natchevaa; “68Ga-DOTATATE-avid pulmonary sclerosing pneumocytoma in a man of North African descent: Case report, imaging findings and pathology” Clinical Imaging