March 2009

Untitled Document

Pathology & Laboratory Medicine News Items – March 2009

 

  • Announcements:
    • Recent Doctoral Degrees Awarded
        • Nichol Holodick successfully defended her thesis, “B1 Cell Development and Signaling on November 8th. Congratulations!
        • Jose Cacicedo successfully defended his thesis, “Palmitate-Induced Apoptosis in Retinal Pericytes: Roles of Oxidative Stress, NF-[kappa]B, Ceramide, Endoplasmic Reticulum Stress and AMP-activated Protein Kinase” on February 25th. Congratulations!
    • Mallory Institute Reunion: On Sunday March 8th, the Department of Pathology and Laboratory Medicine will host a Mallory Institute of Pathology Reunion, reception and tour of our new pathology laboratories at 670 Albany Street, Boston MA from 5:00- 8:00 pm.   We are in particular inviting and encouraging former members of the Mallory Institute to participate. The Mallory Institute of Pathology formally opened in December of 1895. The Institute was a gateway for considerable scientific medical work, and has grown into the new laboratories we have today. Daniel Remick, MD, Chair of the Department invites all current and former members of the Mallory Institute along with our current departmental faculty, residency training program members and all support staff to attend.  This event will occur in conjunction with the USCAP (United States and Canadian Academy of Pathology) Annual Meeting taking place in Boston, March 7-13th. The USCAP is “dedicated to the advancement of Pathology” through seminars, workshops, courses, publications and promoting pathological research. In addition, four wall-mounted panels describing the Mallory Institute of Pathology and its rich history will be unveiled outside the 3rd floor Anatomic Pathology Laboratories at 670 Albany Street.
    • Site Visit: Thanks to all the staff, faculty and residents for your help and support during the ACGME site visit of the pathology residency program. Dr. Rubin from the ACGME was very supportive of the program, providing several creative ideas. The program information form is still available on the G drive under the folder resident manual. Please review it at your convenience. If you have any suggestions to improve the program, please do not hesitate to contact Dr. Carl O’Hara, Dr. Karen Quillen, Dr. Lija Joseph or Mr. Bob Foley.
  • Presentations:
    • Antonio de las Morenas was invited last week to participate and give a presentation on "Problems with FNA specimens in the Differential Diagnosis of Intrathoracic tumors" by the National Health System in Seville, Spain.His presentations were on February 11th.
    • Huihong Xu, Shi Yang, Hongying Huang, Bohdana Burke, Sandra Cerda, Chaline Mack and Michael O’Brien abstract, "Mucin Core Proteins (MUC2 and MUC6) and Transcription Factor CDX2 Expression in Colorectal Serrated Polyps: Correlation with Neoplastic Progression", has been accepted for poster presentation by DDW (Digestive Disease Week) 2009 Annual Meeting (May 30 – June 4). The annual Digestive Disease Week meeting is the world’s largest gathering of physicians and researchers in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.
    • Lija Joseph and Carl O’Hara have been invited to present at the First Annual Boston University Instructional Innovation Conference to be held on Friday, March 27, 2009 from 8:30am-5pm in the Metcalf Trustee Ballroom on the 9th floor of One Silber Way.  The day-long event is co-sponsored by the Office of the Provost and the Center for Excellence in Teaching. Their topic: Successful strategies of curricular integration of Anatomy, Histology, and Pathology at Boston University School of Medicine; Lija Joseph, Alyssa Brown, Rebecca Batiste, Carl O’Hara, Ann Zumwalt, Todd Hoagland and Deborah Vaughan
    • Madhu Jagannathan’s abstract "Toll-like Receptor 4 engagement blocks inflammatory cytokine production by B cells from inflammatory disease patients" has been accepted for an oral presentation at FOCIS in San Francisco this June 11th-15th.
  • Grants
    • The Kurosawa Lab has a newly funded grant!  It is: 5 U19 AI062629 M Coggeshall, PI, Program Director; Shinichiro Kurosawa, Sub-Contract PI, DJ Stearns-Kurosawa, Co-Investigator  NIH/NIAID “Molecular and Immunologic Analysis of the Pathobiology of Human Anthrax” ; 09/01/09 – 08/31/14. In this successful competitive renewal, the major goals are to develop and characterize baboon models of anthrax using virulent and attenuated B.anthracis strains. The baboon models will support and validate research performed by consortium immunologists for vaccine development and studies of adaptive immune responses.
  • Publications:
    • DHK Chui, MH Steinberg.   Laboratory diagnosis of hemoglobinopathies and thalassemias. In:  Hematology: Basic Principles and Practice, 5th edition.  R Hoffman, EJ Benz Jr, SJ Shattil, B Furie, LE Silberstein, P McGlave, HE Heslop. (eds.)  Elsevier, Philadelphia,  pp. 525-533, 2009
    • Zhu, J., J.Z. Sanborn, S. Benz, F. Hsu, C. Szeto, R.M. Kuhn, D.  Karolchik, J. Archie, M.E. Lenburg, L.J. Esserman, W.J. Kent, T. Wang, D. Haussler.  The UCSC Cancer Genomics Browser.  Nature Methods.  In Press.
    • Zhou, J., W. Huang, S. Ibaragi, Y. Ido, X. Wu, Y.O. Alekseyev, M.E.  Lenburg, G. Hu, Z. Luo.  Inactivation of AMPK alters gene expression and promotes the growth of prostate cancer cells.  Oncogene.  In Press.
    • Steiling, K., A.Y. Kadar, A. Bergerat, J. Flanigon, S. Sridhar, V.  Shah, M.E. Lenburg, Q. R. Ahmad, M. Steffen, J.S. Brody, A. Spira. Proteomic differences in large-airway epithelial cells collected from never and current smokers.  PLoS  ONE.  In Press.
    • John Meyers just had a manuscript accepted to the Journal of Immunology entitled: "CLL, B and T cells differ in their response to cyclic nucleotide phosphodiesterase inhibitors" by Meyers JA, Su DW and Lerner A.

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