December 2008

USCAP Accepted Abstracts for Annual Meeting Boston – 2009

  • Platform Presentations
      • Chris D. Andry, Christian Kiriakos, Diego Martinez, and Lisa O’Connor (VP for Nursing at BMC): A Pathology Department-Based Decedent Affairs Office Can Contribute to Improved Organ and Tissue Donation Services”

      • LA Emery, A. de las Morenas, A. Tripathi, P. Sebastiani and CL Rosenberg: “Gene Expression Alterations Associated with Premalignant and Preinvasive Breast Disease”
      • S.Yang , H Xu, H Huang, B Burke, SK Duhon, S Cerda and MJ O’Brien: “CpG Island Methylation in Serrated and Conventional CRC Precursor Neoplasms: How Individual Marker Genes and Panels Relate to Histology and Oncogene Mutation Status”

  • Invited Presentations
      • D.G. Remick, “Immunopathology of bacterial infections” Binford Dammin Infectious Disease Pathology Society
  • Poster Presentations
    • Supraja Narasimhan and David Sherr: “A ROLE FOR THE AhR, AN ENVIRONMENTAL POLLUTANT ACTIVATED RECEPTOR AND TRANSCRIPTION FACTOR, IN MAMMARY TUMOR PROGRESSION”
      • J.M. Cacicedo, E. Chou, N.B. Ruderman, and Y. Ido: “Activation of AMPK by AICAR Inhibits Palmitate-Induced Increases in Ceramide Mass, Endoplasmic Reticulum (ER) Stress, NF-kappaB, and Apoptosis in Cultured Bovine Retinal Pericytes (BRPC).”
      • Sudha Natarajan, Jiyoun Kim, Daniel G. Remick: “Pulmonary Endotoxin Tolerance Protects Against Lung Injury While Maintaining Capacity To Clear Bacterial Pathogens.”
      • AJ Mangini, T Nagai, A Ozonoff, MJ Fritzler, R Lafyatis and J Maguire van Seventer: “Type I Interferons: Regulators of inflammatory T helper cell responses in SLE”
      • Aditi Gurka, Cyrus Vaziri: “Regulation of Rad18 Via the Ataxia Telangiectasia and Rad3 Related (ATR) Kinase”
      • MJ Greene, K Laporte, E Klimtchuk, D Seldin and LH Connors: “Amyloidogenic nature of circulating transthyretin variants, V122I and V30A, and the effect of the NSAID, diflunisal”
      • B.G. Belikoff, S. Hatfield, F. Craciun, J.A. Buras, M. Sitkovsky, and D.G. Remick: “The Adenosinergic A2A Receptor Prevents Exacerbation of Systemic Inflammation and Lung Inflammation Secondary to Polymicrobial Sepsis”
      • D. Horton, D. Remick: “Chemokines Are Selectively Regulated during the Progression of Acute Inflammation”
      • Hongying Huang, Yirong Li, Jonathan Melamed, Peng Lee, Antonio de las Morenas: Increased Lef1 Expression in Metastatic Prostate Cancer”
      • S. Arya, D. Sundararajan, L. Haydt, B. Burke, C. Andry and A. de las Morenas: “Role Of ProEx C And MiB-1 In Evaluation Of Salivary Gland Neoplasms”
      • K. Graham, A. Tripathi, A. de las Morenas, P. Sebastiani, C. Rosenberg: “Genes are differentially expressed in normal appearing breast epithelium between different cohorts of breast cancer patients”
      • B.J. Tierno, B.D. McMillen, D.S. Xu, L. Joseph: “CD87, a Prognostic and Diagnostic Flow Cytometry Marker in Myelodysplastic Syndrome”
      • J. Kim, F. Chiem, S. Natarajan, L. Vaickus and D. Remick: “Anti-Oxidant Taurine Treatment Reduces Pulmonary Inflammation Induced by Allergen and Diesel Particulate Matter Challenge in a Mouse Model of Asthma”
      • Heather Cohen, Shinichiro Kurosawa, DJ Stearns-Kurosawa: “Adiponectin Levels During The Septic Response To B.Anthracis Sterne Strain In Baboons”
      • DJ Stearns-Kurosawa, V Collins, S Freeman, S Kurosawa: “Activated Protein C Substantially Improves Survival in a Baboon Model of Anthrax-mediated Sepsis”
      • JF. Papin, DJ Stearns-Kurosawa, V. Collins, S Freeman, G. Peer, and S. Kurosawa: “STX-1 Non-Human Primate Toxemia Model: Circulating Leukocyte MRNA Changes Coincide With Disease Onset”
      • Dana Semmel and Carl O’Hara: “Morphologic findings in PET positive, tumor negative lymph nodes in l patients with lung cancer”
      • JC Lee, PT Soo Hoo, LH Connors and CJ O’Hara: “Use of ultrastructural immunolabeling (immuno-gold electron microscopy) in the classification of systemic amyloidosis”

Announcements:

  • Dr. Michael O’Brien has been named the new Chair of the New England Pathology Society
  • The 2008 Cytology Proficiency Test was taken by all Cytotechnologists and Cytopathologist at the beginning of the November. We received the results last Monday and everybody passed it with 100% correct answers. Congratulations to all Cytopathology Staff! And special thanks to the proctors, Dr. Andry and Ms. Wirtanen. They also had to pass their own proctor test.
  • Dr. Martin Kroll was recently elected as Program Chair for the Northeast Section of the American Association for Clinical Chemistry (AACC). The position is equivalent to the president elect for the local section. He takes office July 1, 2009 and the following year Dr. Kroll will assume the position as Chair (President in the older terminology). The AACC is one of the largest organizations in clinical Pathology in the world and its annual meeting hosts the largest and most extensive exhibits for Laboratory Medicine in the Western Hemisphere.

Posters:

  • Marc Lenburg gave a poster presentation entitled “Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer” at the NCI Translational Science Conference which was held in Washington, D.C. November 7th – 9th. The poster was highlighted in the Poster Discussion Session entitled “Biomarkers for Lung Cancer Detection & Therapy”.

Presentations:

  • Dr. Kazem Azadzoi presented at the Society of Basic Urology Research (SBUR) Meeting held November 21-24 in Phoenix, AZ.Title of the presentation is: “Oxidative Neural Injury in the Overactive Bladder”

Publications:

  • Chinnappan, D., Qu, X., Xiao, D., Ratnasari, A. and Weber, H.C.: Human Gastrin-Releasing Peptide Receptor Gene Regulation Requires Transcription Factor Binding at Two Distinct CRE Sites. Am J Physiol 2008; 295(1):G153-G162
  • Boback M. Berookhim, Amanjot S. Sethi, C. Charles Wen, Jing Cui, Louis S. Liou| had a manuscript accepted by UIJ: A Cost Comparison of the Diagnostic Modalities Used in the Detection of Urothelial Carcinoma in Patients Undergoing Evaluation for Hematuria. December 2008 publication
  • Rosana Meyer’s manuscript (Rosana D Meyer, David Sacks and Nader Rahimi) IQGAP1-Dependent Signaling Pathway Regulates Endothelial Cell Proliferation and Angiogenesis is accepted for publication in PLos One Journal, November 2008.

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