November 2008
Pathology & Laboratory Medicine News – November 2008
WELCOME to NEW FACES!~
- Brian Japp in the Remick Lab
- Diana Weiner in the Kurosawa Lab
- Sreedevi Srinivasan in the Rahimi Lab
- Pritam Sengupta in the Rahimi Lab
- Dr. Rosana D Meyer, MD. will be joining Dr, Rahimi on Nov. 11th as instructor. Dr. Meyer is studying role of protein ubiquitination in angiogenesis.
Announcements:
- Steven Bogen MD PhD served on the Innovative Technologies for the Molecular Analysis of Cancer (IMAT) grant review study section for the National Cancer Institute, October 15-16, Bethesda, MD
- Steven Bogen MD PhD served on the Clinical Laboratory Standards Institute (CLSI) sub-committee for establishing new practice standards in Immunohistochemistry. The last CLSI guidelines were almost a decade old. Last month (October), the new guidelines document was finished and sent to the CLSI area sub-committee, concluding the committee’s work
- First Year Medical students gain a glimpse of pathology organs as they dissect cadavers in the anatomy lab. The pathology department faculty, staff and senior medical students have initiated a program to demonstrate abnormal organ pathology to the first year medical students. This helps the students gain an understanding of normal and abnormal as they dissect various organ systems. The demonstrations are integrated so that they observe abnormal heart as they dissect normal heart, abnormal uterus as they dissect normal uterus and so on. The second year students are also reminded of the normal histology as they study abnormal pathology in the pathology lab sessions. Please let Drs.Joseph or O’Hara know if you are interested in participating in any of these sessions.
- Walther Pfeifer has successfully passed the Hematology exam and is now officially a diplomat of the American Board of Pathology
- Basic Life Support Certification Renewed for:
- Dr. Sandra Cerda
- Dr. Antonio de las Morenas
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Dr. Jianmin Gan
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Dr. Walther Pfeifer
- Dr. Robert Pistey
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Dr. Daniel Remick
- Dr. Carmen Sarita-Reyes
n Graduate Student News:
o Sudha Natarajan’s, (J. Kim and D. G. Remick) manuscript entitled “Acute Pulmonary LPS Tolerance Decreases TNFa Without Reducing Neutrophil Recruitment” was accepted for publication in The Journal of Immunology on October 20th.
o Jillian Richmond presented a poster this past weekend at the New England Immunology Conference. The title was “Effects of Components of the M TUBERCULOSIS strain H37Rv on T cell Migration.”
n Grants
o The Clinical and Translational Science Institute hereby awards Nader Rahimi a pilot grant in the amount of $40,000.00 for the period of November 1, 2008 through April 30, 2009. The award is pursuant to your application entitled: Identification of Novel Anti-Angiogenesis Agent for Treatment of Angiogenesis-associated Eye Diseases
n Posters:
o Some photos from the CAP meeting in San Diego
§
The first one is Sara Koenig next to her poster
§ The second is Dr. Eugene Pearlman and Bethany Tierno
§ The third is Bethany Tierno next to her poster
§ Barbara Nikolajczyk’s undergraduate student, Julia Jezmir, presented a poster at the UROP symposium on the Charles River Campus entitled “The Role of the Inflammasome and TLR family hyper-activation in Type 2 Diabetes and Crohn’s Disease” held on Oct 17th.
n Presentations:
o Dr. Michael O’Brien will present at the upcoming New England Pathologists Society Meeting on Nov 18th. He will be giving the Stanley L Robbins lecture, “Serrated Polyp Pathway to Colorectal Cancer” and 3 of our residents, Dr. Bethany J. Tierno, Dr. Hongying Huang and Dr. Nalini Balgobin will be presenting a slide seminar related to the lecture topic
o John Kim, PhD went to Nuremberg, Germany on October 5, 2008 for an invited presentation titled “TNF-a Inhibitors Effectively Treat Asthma” during 2nd World Conference on Magic Bullets: Celebrating the 100th Anniversary of the Nobel Prize Awarded to Paul Ehrlich
o Steven Bogen MD PhD presented at the NCI’s Innovative Molecular Analysis Technologies annual meeting in Cambridge, MA, Sunday October 26, 2008 in the session entitled “Technologies to capture circulating tumor cells“. Dr. Bogen’s presentation was entitled “Performance Characteristics of a New CTC Enrichment Method Using a Negative Selection Strategy”
o Dr. Kazem Azadzoi has been selected as a guest speaker to give State of the Art lecture on Oxidative Stress and Erectile Dysfunction in Gwangju International Symposium on Sexual Medicine to be held on October 31 in South Korea.
n Publications:
o Beane, J.E., A. Spira, M.E. Lenburg. “Clinical impact of high- throughput gene expression studies in lung cancer.” Journal of Thoracic Oncology. In Press. This paper reviews work that has been done using genome-wide gene- expression profiling to develop clinically relevant tools for the diagnostic and prognostic evaluation of lung cancer patients
o Seshi Sompuram PhD and Steven Bogen MD PhD had a manuscript accepted to “Applied Immunohistochemistry and Molecular Morphology”. The manuscript is entitled “Experimental validation of peptide immunohistochemistry controls“
o Ratner DM, Cui J, Steffen M, Moore LL, Robbins PW, Samuelson J. Changes in the N-glycome (glycoproteins with Asn-linked glycans) of Giardia lamblia with differentiation from trophozoites to cysts. Eukaryot Cell. 2008 Sep 26. [Epub ahead of print] PMID: 18820077 [PubMed – as supplied by publisher]
o Sedgewick AE, Timofeev N, Sebastiani P, So JCC, Ma ESK, Chan LC, Fucharoen G, Fucharoen S, Barbosa CG, Vardarajan BN, Farrer LA, Baldwin CT, Steinberg MH, Chui DHK. BCL11A is a major HbF quantitative trait locus in three different populations with beta-hemoglobinopathies. Blood Cells, Molecules, and Diseases 41: 255-258, 2008.
o Madziar B, Shah S, Brock M, Burke R, Lopez-Coviella I, Nickel AC, Cakal EB, Blusztajn JK, Berse B. NGF regulates the expression of the cholinergic locus and the high affinity choline transporter via the Akt/PKB signaling pathway. J Neurochem. 2008 Sep 13. [Epub ahead of print] PMID: 18793330 [PubMed – as supplied by publisher]