Recent Publication
Dr. Hassan Dashti, Instructor at Massachusetts General Hospital received a BNORC Pilot and Feasibility award in 2021 for his project entitled “Phenome-wide interactions between obesity genetic risk and lifestyle traits in an electronic health record biobank”. The project has resulted in a 2022 publication in BMC Medicine. Among patients in a clinical biobank, the investigators found […]
New Publication from Center Members John Campbell, Bradford Lowell, Linus Tsai and Collaborators
New Publication from Center Members Drs. John Campbell, Bradford Lowell and Linus Tsai. See below for publication information. Jenkang Tao1,2,5, John N. Campbell1,3,5,6, Linus T. Tsai1, Chen Wu1, Stephen D. Liberles2,4 and Bradford B. Lowell1,2,6,7. Highly Selective Brain-to-Gut Communication via Genetically-Defined Vagus Neurons. Neuron (in press). 1Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth […]
New Publication from Center Members Dr. Melanie Schorr Haines, Dr. Laura Dichtel and Karen Miller
New Publication from Center Members Dr. Melanie Schorr Haines and Dr. Laura Dichtel. See below for publication information and click here to read the article. Haines MS, Dichtel LE, Santoso K, Torriani M, Miller KK, Bredella MA. Association between muscle mass and insulin sensitivity independent of detrimental adipose depots in young adults with overweight/obesity. International […]
Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
Source: ScienceDirect Lipid droplets (LDs) store lipids for energy and are central to cellular lipid homeostasis. The mechanisms coordinating lipid storage in LDs with cellular metabolism are unclear but relevant to obesity-related diseases. Here we utilized genome-wide screening to identify genes that modulate lipid storage in macrophages, a cell type involved in metabolic diseases. Among […]