Tatyana Sharova, MD

sharova

Research Instructor

Administrative Office

Boston University School of Medicine, Dept of Dermatology

609 Albany Street, J-405, Boston, MA 02118
Tel: 617-638-5553
Fax: 617-638-5515

Education

  1. Chuvash State University School of Medicine, Cheboksary, Russia – MD (1993-1999)
  2. Department of Dermatology, Boston University School of Medicine – Postdoctoral Training (2001-2008)

Clinical Specialties and Research Interests

  • Skin Development, Hair Cycling, Epigenetics, Epithelial Stem Cells, Pigmentation and Melanoma

Selected Publications

  1. Mardaryev AN, Meier N, Poterlowicz K, Sharov AA, Sharova TY, Ahmed MI, Rapisarda V, Lewis C, Fessing MY, Ruenger TM, Bhawan J, Werner S, Paus R, Botchkarev VA. Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cellsĀ  to promote epidermal regeneration after injury. Development. 2011;138:4843-52.
  2. Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA. p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011; 194:825-39.
  3. Sharov AA, Schroeder M, Sharova TY, Peters EM, Botchkarev VA. Matrix metalloproteinase-9 is involved in regulation of hair canal formation. J Invest Dermatol. 2011; 131, 257-60.
  4. Sharov AA, Mardaryev AN, Sharova TY, Grachtchouk M, Atoyan R, Byers HR, Seykora JT, Overbeek P, Dlugosz A, Botchkarev VA. BMP antagonist Noggin promotes skin tumorigenesis via stimulation of the Wnt and Shh signaling pathways. Amer J Pathol, 2009, 175:1303-1314.
  5. Sharov AA, Sharova TY, Mardariev AN, Tommasi di Vignano A, Atoyan R, Weiner L, Yang S, Brissette JL, Dotto GP, Botchkarev VA. BMP signaling controls hair follicle size and modulates the expression of cell cycle-associated genes. Proc Natl Acad Sci USA, 2006, 103, 18166-18171.
  6. Sharov AA, Sharova TY, Mardaryev AN, di Vignano AT, Atoyan R, Weiner L, Yang S, Brissette JL, Dotto GP, Botchkarev VA. Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes. Proc Natl Acad Sci USA. 2006, 103: 18166-71 [equal contribution as first author].
  7. Fessing MY, Sharova TY, Sharov AA, Atoyan R, Botchkarev VA. Involvement of the Edar signaling in the control of hair follicle involution (catagen). Am J Pathol. 2006, 169: 2075-84 [equal contribution as first author].