Vladimir Botchkarev, MD, PhD is Research Associate Professor in the Department of Dermatology. He received his medical training at Chuvash State University in Cheboksary, Russian and his doctoral training at People’s Friendship University in Moscow, Russia. He was a recipient of the Research Career Development Award from the Dermatology Foundation and Independent Scientist Award from the National Institutes of Health. He is also a recipient of the research grants from the NIAMS and NCI. His name was included in the books 2000 Outstanding Scientists of the 21st Century, Great Minds of the 21st Century and Who is Who in Medicine. His primary research interests are the molecular mechanisms of hair growth and pathobiology of different forms of hair loss.
- Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences
- Adjunct Professor, Pathology & Laboratory Medicine, Boston University School of Medicine
- Chuvash State University, MD
- Peoples' Friendship University of Russia, PhD
- Published on 9/1/2017
Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY. 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells. PLoS Genet. 2017 Sep; 13(9):e1006966. PMID: 28863138.
- Published on 6/6/2017
Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A. p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct; 137(10):2157-2167. PMID: 28595999.
- Published on 6/2/2017
Botchkarev VA. Second International Symposium-Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases. J Invest Dermatol. 2017 Aug; 137(8):1604-1608. PMID: 28583676.
- Published on 5/1/2017
Botchkarev VA. The Molecular Revolution in Cutaneous Biology: Chromosomal Territories, Higher-Order Chromatin Remodeling, and the Control of Gene Expression in Keratinocytes. J Invest Dermatol. 2017 May; 137(5):e93-e99. PMID: 28411854.
- Published on 8/1/2016
Botchkarev VA, Mardaryev AN. Repressing the Keratinocyte Genome: How the Polycomb Complex Subunits Operate in Concert to Control Skin and Hair Follicle Development. J Invest Dermatol. 2016 08; 136(8):1538-40. PMID: 27450498.
- Published on 3/1/2016
Botchkarev VA, Sharov AA. Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions toward Clinical Reality. J Invest Dermatol. 2016 Mar; 136(3):557-9. PMID: 26902124.
- Published on 12/28/2015
Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA. Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4; 212(1):77-89. PMID: 26711500.
- Published on 11/1/2015
Botchkarev VA. Integration of the Transcription Factor-Regulated and Epigenetic Mechanisms in the Control of Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Nov; 17(2):30-2. PMID: 26551942.
- Published on 7/1/2015
Botchkarev VA. Epigenetic Regulation of Epidermal Development and Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Jul; 17(1):18-9. PMID: 26067308.
- Published on 9/1/2014
Mardaryev AN, Gdula MR, Yarker JL, Emelianov VU, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Joffe B, Solovei I, Chambon P, Botchkarev VA, Fessing MY. p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Sep; 141(17):3437. PMID: 25139860.
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