Valentina Sabino, PhD

Associate Professor, Pharmacology & Experimental Therapeutics

Valentina Sabino
72 E. Concord St Housman (R)


Dr. Sabino is co-director of the Laboratory of Addictive Disorders, and is currently researching the neurobiology of addiction and stress-related disorders. Studies on addiction aim to understand the neurobiological substrates of alcohol abuse and dependence by exploring the role of neurochemical systems in excessive alcohol drinking.

Dr. Sabino is working toward the development of new therapeutic agents to alleviate alcohol addiction. Animal models for excessive drinking are studied in order to identify compounds for potential clinical development. Research is also conducted on the neurobiology of stress-related disorders such as anxiety and depression.

The approach of the laboratory is interdisciplinary, involving behavioral neuroscience, neuropharmacology, neuroanatomy, biochemistry and molecular biology.

Dr. Sabino co-directs a graduate course in Behavioral Pharmacology which examines the interaction between behavior and classes of drugs that affect the central nervous system giving emphasis on how behavioral studies can assist in our understanding of mental disorders.

Other Positions

  • Associate Professor, General Psychiatry, Psychiatry, Boston University School of Medicine
  • Co-Director, Laboratory of Addictive Disorders, Pharmacology & Experimental Therapeutics, Boston University School of Medicine
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Division of Graduate Medical Sciences


  • University of Rome, PhD
  • University of Palermo, MS
  • University of Palermo, BS
  • University of Palermo, PharmD


  • Published on 3/19/2018

    Moore CF, Panciera JI, Sabino V, Cottone P. Neuropharmacology of compulsive eating. Philos Trans R Soc Lond B Biol Sci. 2018 Mar 19; 373(1742). PMID: 29352024.

    Read at: PubMed
  • Published on 2/15/2018

    Logrip ML, Walker JR, Ayanwuyi LO, Sabino V, Ciccocioppo R, Koob GF, Zorrilla EP. Evaluation of Alcohol Preference and Drinking in msP Rats Bearing a Crhr1 Promoter Polymorphism. Front Psychiatry. 2018; 9:28. PMID: 29497387.

    Read at: PubMed
  • Published on 10/31/2017

    Moore CF, Schlain GS, Mancino S, Sabino V, Cottone P. A behavioral and pharmacological characterization of palatable diet alternation in mice. Pharmacol Biochem Behav. 2017 Dec; 163:1-8. PMID: 29097161.

    Read at: PubMed
  • Published on 8/24/2017

    Moore CF, Sabino V, Koob GF, Cottone P. Neuroscience of Compulsive Eating Behavior. Front Neurosci. 2017; 11:469. PMID: 28883784.

    Read at: PubMed
  • Published on 1/1/2017

    Sabino V, Cottone P. Sigma Receptors and Alcohol Use Disorders. Handb Exp Pharmacol. 2017; 244:219-236. PMID: 28039543.

    Read at: PubMed
  • Published on 1/1/2017

    Sabino V, Hicks C, Cottone P. Sigma Receptors and Substance Use Disorders. Adv Exp Med Biol. 2017; 964:177-199. PMID: 28315272.

    Read at: PubMed
  • Published on 12/6/2016

    Moore CF, Sabino V, Koob GF, Cottone P. Pathological Overeating: Emerging Evidence for a Compulsivity Construct. Neuropsychopharmacology. 2017 Jun; 42(7):1375-1389. PMID: 27922596.

    Read at: PubMed
  • Published on 10/6/2016

    Ferragud A, Howell AD, Moore CF, Ta TL, Hoener MC, Sabino V, Cottone P. The Trace Amine-Associated Receptor 1 Agonist RO5256390 Blocks Compulsive, Binge-like Eating in Rats. Neuropsychopharmacology. 2017 Jun; 42(7):1458-1470. PMID: 27711047.

    Read at: PubMed
  • Published on 7/4/2016

    Iemolo A, Seiglie M, Blasio A, Cottone P, Sabino V. Pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nucleus of the amygdala induces anxiety via melanocortin receptors. Psychopharmacology (Berl). 2016 Sep; 233(17):3269-77. PMID: 27376948.

    Read at: PubMed
  • Published on 10/14/2015

    Valenza M, DiLeo A, Steardo L, Cottone P, Sabino V. Ethanol-related behaviors in mice lacking the sigma-1 receptor. Behav Brain Res. 2016 Jan 15; 297:196-203. PMID: 26462569.

    Read at: PubMed

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