Michael L. Alosco, PhD

Associate Professor, Boston University Chobanian & Avedisian School of Medicine

Biography

Dr. Alosco is a licensed clinical neuropsychologist and serves as the co-director of the Boston University Alzheimer’s Disease Research Center Clinical Core and is a lead investigator of the BU CTE Center. He also oversees Neuropsychology for the Memory and Aging Clinic at Boston Medical Center. He completed his undergraduate studies at Providence College and he earned his doctoral degree in clinical psychology, with a focus on neuropsychology, in 2015 from Kent State University. He completed his clinical internship in neuropsychology at the VA Boston Healthcare System. Dr. Alosco completed his post-doctoral studies in neuropsychology via NIH-funded training Awards (T32, F32) at the Boston University Alzheimer’s Disease Research Center and CTE Center. In 2018, he became an Assistant Professor of Neurology at the Chobanian and Avedisian School of Medicine and he was promoted to Associate Professor in 2019. Dr. Alosco has >150 peer-reviewed publications, is the PI of multiple NIH funded grants, is the recipient of an NIH/NINDS K23 Award, is the Project Lead of an NIH-funded multisite U54 grant, and serves as aco-investigator on numerous federal and non-federal funded grants. He has also written numerous book chapters, and he is the co-Editor of the Oxford Handbook of Adult Cognitive Disorders which was published by Oxford University Press in 2019.

Dr. Alosco has an active and established research program that has a thematic focus on three areas: (1) the relationship between repetitive head impacts (RHI) and traumatic brain injury (TBI) with a later-life cognitive and neuropsychiatric decline, as well as neurodegenerative disease(s); (2) the contribution of cerebrovascular disease to the clinical and neuropathological expression of CTE, AD, and AD-related dementias (ADRD); and (3) in vivo biomarker development for CTE, AD, and ADRD with a focus on tau PET imaging, structural MRI, and blood-based biomarkers.

Publications

  • Published 9/22/2025

    Subramanian ML, Sampani K, Ness S, Tuz-Zahra F, Alluri S, Chen X, Siegel NH, Aytan N, Xia W, Tripodis Y, Alosco ML, Stein TD. Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy. J Alzheimers Dis. 2025 Sep 22; 13872877251378759. PMID: 40982223.

    Read at: PubMed

  • Published 9/1/2025

    Alosco ML, Morrison M, Au R, Steinberg EG, Mwicigi J, Ly M, Altaras C, Lenio S, Abdennadher M, O'Connor MK, Tripodis Y, Palmisano J, Dixon D, Martin B, Schneider G, Groh JR, Ellison A, Sheppard D, Farris CW, Nowinski C, Cantu RC, Turk KW, Farrer L, Jun G, Goldstein LE, Qiu WQ, Stein TD, Budson AE, McKee AC, Mez J. Boston University Alzheimer's Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer's disease and related dementias. Alzheimers Dement. 2025 Sep; 21(9):e70654. PMID: 40923312.

    Read at: PubMed

  • Published 8/16/2025

    Gao A, Tuz-Zahra F, Vig V, Zeng R, Tripodis Y, Stein TD, Alosco ML, Ness S, Chen X, Siegel N, Subramanian ML. The Association between Retinal Vascular Occlusions and Dementia: A UK Biobank Retrospective Longitudinal Study. Ophthalmol Retina. 2025 Aug 16. PMID: 40825393.

    Read at: PubMed

  • Published 8/6/2025

    Ness S, Sampani K, Tuz-Zahra F, Aytan N, Alluri S, Fiorello MG, Chen X, Siegel NH, Alosco ML, Xia W, Tripodis Y, Stein TD, Subramanian ML. Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease. Sci Rep. 2025 Aug 06; 15(1):28720. PMID: 40770000.

    Read at: PubMed

  • Published 6/25/2025

    Fang Y, Chen J, Mez J, Satizabal CL, Alosco ML, Qiu WQ, Doyle MF, Murabito JM, Lunetta KL. Modeling heterogeneity in cognitive trajectories in the Framingham Heart Study. Front Aging Neurosci. 2025; 17:1471154. PMID: 40636900.

    Read at: PubMed

Education

  • Kent State University, PhD
  • Kent State University, MA
  • Providence College, BA