Marie-Helene Saint-Hilaire, MD

Professor, Neurology

Marie-Helene Saint-Hilaire
75 E. Newton St Collamore Building


Dr. Saint-Hilaire received her MD from the Université de Montréal, Canada in 1980 and completed her Neurology residency at the Montréal Neurological Institute (MNI). She then completed a year of fellowship in epilepsy at the MNI, followed by a 3-year movement disorders fellowship working in varied institutions consisting of one year in Paris with Pr. Yves Agid, one year in New York at Columbia Presbyterian Hospital with Dr. Stanley Fahn, and one year at Boston University with Dr. Robert Feldman. In 1988, she joined Boston University Department of Neurology.

Dr. Saint-Hilaire is board-certified in Neurology and is fellowship trained in Movement Disorders. She is dedicated to the delivery of highly specialized and compassionate care. This care is aimed at improving the quality of life of Parkinson’s disease patients and their families. Her clinical practice includes the diagnosis and management of all of the neurological movement disorders.

Additionally, she is the Director of the American Parkinson Disease Association Center for Advanced Research at Boston University. She has participated in more than 100 research trials and has written more than 100 articles and book chapters. Her research interests include studying new therapies that may modify disease progression and/or treat symptoms and complications of therapy. Additionally, she is interested in research investigating environmental and genetic causes of PD. She frequently collaborates with other disciplines to design and implement clinical trials. She is a member of the Parkinson Study Group (PSG), the Huntington Study Group (HSG), and the Movement Disorder Society. She currently is a member of the PSG Scientific Review Committee. She has served on the Scientific Advisory Board for the American Parkinson Disease Association since 2007.

Dr. Saint-Hilaire directs the movement disorders fellowship at BUSM. She is actively involved in the training of residents and medical students at BUSM. She has received the Teaching Award on three occasions, and the Mentorship Award on one occasion, both presented by Neurology Residents.

As the Medical Director of the American Parkinson Disease Association Information and Referral Center, she is dedicated to the New England Parkinson community and has provided over 200 presentations to health professional and lay groups. She is an advisor to the APDA Massachusetts Chapter. In 2016, she received the Shawn Thornton Award for Excellence in Support of the Parkinson’s Community.

Other Positions

  • Ad Interim Chair, Neurology, Boston University School of Medicine


  • Université de Montréal, MD
  • Collège Marie de France, BA


  • Published on 3/31/2019

    Reynolds GO, Saint-Hilaire M, Thomas CA, Barlow DH, Cronin-Golomb A. Cognitive-Behavioral Therapy for Anxiety in Parkinson's Disease. Behav Modif. 2019 Mar 31; 145445519838828. PMID: 30931594.

    Read at: PubMed
  • Published on 2/1/2019

    LeWitt PA, Hauser RA, Pahwa R, Isaacson SH, Fernandez HH, Lew M, Saint-Hilaire M, Pourcher E, Lopez-Manzanares L, Waters C, Rudzínska M, Sedkov A, Batycky R, Oh C. Safety and efficacy of CVT-301 (levodopa inhalation powder) on motor function during off periods in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Neurol. 2019 Feb; 18(2):145-154. PMID: 30663606.

    Read at: PubMed
  • Published on 2/1/2019

    Ellis TD, Cavanaugh JT, DeAngelis T, Hendron K, Thomas CA, Saint-Hilaire M, Pencina K, Latham NK. Comparative Effectiveness of mHealth-Supported Exercise Compared With Exercise Alone for People With Parkinson Disease: Randomized Controlled Pilot Study. Phys Ther. 2019 Feb 01; 99(2):203-216. PMID: 30715489.

    Read at: PubMed
  • Published on 9/23/2018

    Raje P, Ning S, Branson C, Saint-Hilaire M, de Leon MP, DePold Hohler A. Self-Reported Exercise Trends in Parkinson's Disease Patients. Complement Ther Med. 2019 Feb; 42:37-41. PMID: 30670269.

    Read at: PubMed
  • Published on 7/1/2018

    Sprague Martinez L, Thomas CA, Saint-Hilaire M, McLaren J, Young J, Habermann B, Tickle-Degnen L. Using a Macro Social Work Strategy to Improve Outreach in Parkinson's Disease Research. Soc Work. 2018 Jul 01; 63(3):265-268. PMID: 29722873.

    Read at: PubMed
  • Published on 12/4/2017

    Goldman JG, Andrews H, Amara A, Naito A, Alcalay RN, Shaw LM, Taylor P, Xie T, Tuite P, Henchcliffe C, Hogarth P, Frank S, Saint-Hilaire MH, Frasier M, Arnedo V, Reimer AN, Sutherland M, Swanson-Fischer C, Gwinn K, Kang UJ. Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features. Mov Disord. 2018 02; 33(2):282-288. PMID: 29205509.

    Read at: PubMed
  • Published on 9/8/2017

    Gunnery SD, Naumova EN, Saint-Hilaire M, Tickle-Degnen L. Mapping spontaneous facial expression in people with Parkinson's disease: A multiple case study design. Cogent Psychol. 2017; 4. PMID: 29607351.

    Read at: PubMed
  • Published on 7/5/2016

    Frank S, Testa CM, Stamler D, Kayson E, Davis C, Edmondson MC, Kinel S, Leavitt B, Oakes D, O'Neill C, Vaughan C, Goldstein J, Herzog M, Snively V, Whaley J, Wong C, Suter G, Jankovic J, Jimenez-Shahed J, Hunter C, Claassen DO, Roman OC, Sung V, Smith J, Janicki S, Clouse R, Saint-Hilaire M, Hohler A, Turpin D, James RC, Rodriguez R, Rizer K, Anderson KE, Heller H, Carlson A, Criswell S, Racette BA, Revilla FJ, Nucifora F, Margolis RL, Ong M, Mendis T, Mendis N, Singer C, Quesada M, Paulsen JS, Brashers-Krug T, Miller A, Kerr J, Dubinsky RM, Gray C, Factor SA, Sperin E, Molho E, Eglow M, Evans S, Kumar R, Reeves C, Samii A, Chouinard S, Beland M, Scott BL, Hickey PT, Esmail S, Fung WL, Gibbons C, Qi L, Colcher A, Hackmyer C, McGarry A, Klos K, Gudesblatt M, Fafard L, Graffitti L, Schneider DP, Dhall R, Wojcieszek JM, LaFaver K, Duker A, Neefus E, Wilson-Perez H, Shprecher D, Wall P, Blindauer KA, Wheeler L, Boyd JT, Houston E, Farbman ES, Agarwal P, Eberly SW, Watts A, Tariot PN, Feigin A, Evans S, Beck C, Orme C, Edicola J, Christopher E. Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial. JAMA. 2016 Jul 5; 316(1):40-50. PMID: 27380342.

    Read at: PubMed
  • Published on 7/1/2016

    Ellis T, Tickle-Degnen L, Saint-Hilaire M. Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease. JAMA Neurol. 2016 07 01; 73(7):892-3. PMID: 27243424.

    Read at: PubMed
  • Published on 6/3/2016

    Ma HI, Saint-Hilaire M, Thomas CA, Tickle-Degnen L. Stigma as a key determinant of health-related quality of life in Parkinson's disease. Qual Life Res. 2016 Dec; 25(12):3037-3045. PMID: 27259581.

    Read at: PubMed

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