Larry Culpepper, MD

Professor, Family Medicine

Larry Culpepper
(617) 414-6225


Dr. Culpepper, Professor of Family Medicine, was the founding Chairman of the Department. He received his M.D from Baylor College of Medicine and his M.P.H. from Boston University. He has served as President of the North American Primary Care Group (NAPCRG), Chairman of the Research Committee of the Society of Teachers of Family Medicine (STFM), and is the Chairman of the Board of Rhode Island Public Health Foundation. He is a Primary Care Fellow of the Federal Health Resources and Services Administration, and has chaired or served as a member of research grant review committees for 5 NIH and other federal agencies. He has received the STFM Excellence in Education, the STFM-NAPCRG Hames Research awards, and the Maurice Wood Award for Lifetime Contribution to Primary Care Research (2010) and was elected to the Institute of Medicine in 1998. The BU School of Public Health recognized him with its 2008 BUSPH Distinguished Alumni Award. He has conducted research in otitis media, and school-based and community interventions to improve pregnancy outcomes and to prevent teen pregnancies and has been the principal investigator of an AHRQ funded center for patient safety research devoted to low income and minority vulnerable populations in ambulatory care settings, principal investigator of interventions to improve the care of uninsured patients and urban patients with diabetes and depression, co-principal investigator of a study to decrease delays in CHC patient follow-up for abnormal mammography, and co-investigator of a long term study of the course of anxiety disorders in primary care settings. Dr Culpepper co-chaired a panel on Otitis Media with Effusion for the American Academy of Family Physicians, the American Academy of Pediatrics, and the American Academy of Otolaryngology-Head and Neck Surgery, and is a member of the AAP-AAFP panel on acute otitis media. He founded and chaired the board of the Rhode Island Public Health Foundation (1992-2011). He is a member of The Depression and Bipolar Support Alliance and the Anxiety Disorders Association of America Scientific Advisory Boards. He currently is the primary care member of an Institute of Medicine Committee on the Assessment of Ongoing Efforts in the Treatment of PTSD (2011-15). He was the initial family medicine editor of UpToDate and is the editor of the Journal of Clinical Psychiatry Primary Care Companion.

Other Positions

  • Active Staff Privileges, Family Medicine, Boston Medical Center


  • Baylor University, MD
  • Boston University, MPH
  • Baylor University, BS


  • Published on 7/1/2017

    McIntyre RS, Best MW, Bowie CR, Carmona NE, Cha DS, Lee Y, Subramaniapillai M, Mansur RB, Barry H, Baune BT, Culpepper L, Fossati P, Greer TL, Harmer C, Klag E, Lam RW, Wittchen HU, Harrison J. The THINC-Integrated Tool (THINC-it) Screening Assessment for Cognitive Dysfunction: Validation in Patients With Major Depressive Disorder. J Clin Psychiatry. 2017 Jul; 78(7):873-881. PMID: 28858441.

    Read at: PubMed
  • Published on 3/2/2017

    Culpepper L. Enduring Truths. Prim Care Companion CNS Disord. 2017 Mar 02; 19(1). PMID: 28257171.

    Read at: PubMed
  • Published on 5/26/2016

    Kornstein SG, Kunovac JL, Herman BK, Culpepper L. Recognizing Binge-Eating Disorder in the Clinical Setting: A Review of the Literature. Prim Care Companion CNS Disord. 2016; 18(3). PMID: 27733955.

    Read at: PubMed
  • Published on 5/1/2016

    Culpepper L. Impact of anxious symptoms and comorbid anxiety disorders on functional impairment in depressed patients. J Clin Psychiatry. 2016 May; 77(5):e604. PMID: 27249089.

    Read at: PubMed
  • Published on 3/3/2016

    Culpepper L. Behavioral Health and Primary Care: A Status Report. Prim Care Companion CNS Disord. 2016; 18(1). PMID: 27247846.

    Read at: PubMed
  • Published on 1/1/2016

    Culpepper L. Functional impairment and improvement in depression. J Clin Psychiatry. 2016 Jan; 77(1):e35. PMID: 26845279.

    Read at: PubMed
  • Published on 12/31/2015

    Culpepper L, Wingertzahn MA. Over-the-Counter Agents for the Treatment of Occasional Disturbed Sleep or Transient Insomnia: A Systematic Review of Efficacy and Safety. Prim Care Companion CNS Disord. 2015; 17(6). PMID: 27057416.

    Read at: PubMed
  • Published on 9/3/2015

    Mitchell SE, Martin JM, Krizman K, Sadikova E, Culpepper L, Stewart SK, Brown JR, Jack BW. Design and rationale for a randomized controlled trial to reduce readmissions among patients with depressive symptoms. Contemp Clin Trials. 2015 Nov; 45(Pt B):151-6. PMID: 26343332.

    Read at: PubMed
  • Published on 9/1/2015

    Culpepper L, Muskin PR, Stahl SM. Major Depressive Disorder: Understanding the Significance of Residual Symptoms and Balancing Efficacy with Tolerability. Am J Med. 2015 Sep; 128(9 Suppl):S1-S15. PMID: 26337210.

    Read at: PubMed
  • Published on 7/1/2015

    Culpepper L. Neuroanatomy and physiology of cognition. J Clin Psychiatry. 2015 Jul; 76(7):e900. PMID: 26231020.

    Read at: PubMed

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