Kenneth H. Albrecht, PhD

Assistant Professor, Biomedical Genetics

Kenneth Albrecht
(617) 638-5821
75 E. Newton St Evans Building

Biography

Research in my laboratory is aimed at understanding the molecular mechanisms of cell fate specification during mammalian sex determination and fetal gonad organogenesis. I am broadly trained in classical genetics, molecular genetics, genomics and developmental biology, and have published widely in the field of mouse genetics and specifically in the developmental genetics of gonad organogenesis and sex determination.

Education

  • University of Connecticut, PhD
  • State University of New York at Stony Brook, BS

Publications

  • Published on 10/4/2016

    Wake C, Labadorf A, Dumitriu A, Hoss AG, Bregu J, Albrecht KH, DeStefano AL, Myers RH. Novel microRNA discovery using small RNA sequencing in post-mortem human brain. BMC Genomics. 2016 Oct 04; 17(1):776. PMID: 27716130.

    Read at: PubMed
  • Published on 4/5/2012

    Correa SM, Washburn LL, Kahlon RS, Musson MC, Bouma GJ, Eicher EM, Albrecht KH. Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway. PLoS Genet. 2012; 8(4):e1002569. PMID: 22496664.

    Read at: PubMed
  • Published on 11/1/2009

    Pazin DE, Albrecht KH. Developmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation. Dev Dyn. 2009 Nov; 238(11):2877-90. PMID: 19842175.

    Read at: PubMed
  • Published on 4/1/2009

    Lee HJ, Pazin DE, Kahlon RS, Correa SM, Albrecht KH. Novel markers of early ovarian pre-granulosa cells are expressed in an Sry-like pattern. Dev Dyn. 2009 Apr; 238(4):812-25. PMID: 19301398.

    Read at: PubMed
  • Published on 12/24/2008

    Liu P, Pazin DE, Merson RR, Albrecht KH, Vaziri C. The developmentally-regulated Smoc2 gene is repressed by Aryl-hydrocarbon receptor (Ahr) signaling. Gene. 2009 Mar 15; 433(1-2):72-80. PMID: 19146932.

    Read at: PubMed
  • Published on 10/1/2008

    Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 2008 Oct; 8(4):310-7. PMID: 18840361.

    Read at: PubMed
  • Published on 1/1/2008

    Izvolsky KI, Lu J, Martin G, Albrecht KH, Cardoso WV. Systemic inactivation of Hs6st1 in mice is associated with late postnatal mortality without major defects in organogenesis. Genesis. 2008 Jan; 46(1):8-18. PMID: 18196599.

    Read at: PubMed
  • Published on 9/11/2007

    Bouma GJ, Washburn LL, Albrecht KH, Eicher EM. Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice. Proc Natl Acad Sci U S A. 2007 Sep 18; 104(38):14994-9. PMID: 17848526.

    Read at: PubMed
  • Published on 9/15/2005

    Thevenet L, Albrecht KH, Malki S, Berta P, Boizet-Bonhoure B, Poulat F. NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY. J Biol Chem. 2005 Nov 18; 280(46):38625-30. PMID: 16166090.

    Read at: PubMed
  • Published on 7/1/2005

    Bouma GJ, Albrecht KH, Washburn LL, Recknagel AK, Churchill GA, Eicher EM. Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells. Development. 2005 Jul; 132(13):3045-54. PMID: 15944188.

    Read at: PubMed

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