John H. Connor, PhD

Member, Bioinformatics Graduate Program

John Connor
617.638.0339
72 E. Concord St Housman (R)

Biography

My laboratory studies the virus-host interaction. We take a variety of approaches from genetic to systems biology to biochemistry and molecular biology. We are studying how viruses take over the cellular protein synthesis apparatus, how cells effectively fight virus infection, and how the host responds to infection with viruses that cause hemorrhagic fever.

Other Positions

  • Associate Professor, Microbiology, Boston University School of Medicine
  • Faculty, National Emerging Infectious Disease Lab, Boston University
  • Graduate Faculty (Primary Mentor of Grad Students), Boston University School of Medicine, Graduate Medical Sciences
  • Member, Genome Science Institute, Boston University

Education

  • Duke University, PhD
  • Swarthmore College, BA

Classes Taught

  • GMSFC702
  • GMSMI823

Publications

  • Published on 6/16/2020

    Speranza E, Caballero I, Honko AN, Johnson JC, Bohannon JK, Evans DeWald L, Gerhardt DM, Sword J, Hensley LE, Bennett RS, Connor JH. Previremic Identification of Ebola or Marburg Virus Infection Using Integrated Host-Transcriptome and Viral Genome Detection. mBio. 2020 Jun 16; 11(3). PMID: 32546624.

    Read at: PubMed
  • Published on 4/8/2020

    Greenberg A, Huber BR, Liu DX, Logue JP, Hischak AMW, Hart RJ, Abbott M, Isic N, Hisada YM, Mackman N, Bennett RS, Hensley LE, Connor JH, Crossland NA. Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik). Am J Pathol. 2020 Jul; 190(7):1449-1460. PMID: 32275904.

    Read at: PubMed
  • Published on 2/12/2020

    Yurdakul C, Avci O, Matlock A, Devaux AJ, Quintero MV, Ozbay E, Davey RA, Connor JH, Karl WC, Tian L, Ünlü MS. High-Throughput, High-Resolution Interferometric Light Microscopy of Biological Nanoparticles. ACS Nano. 2020 02 25; 14(2):2002-2013. PMID: 32003974.

    Read at: PubMed
  • Published on 12/12/2018

    Sebba D, Lastovich AG, Kuroda M, Fallows E, Johnson J, Ahouidi A, Honko AN, Fu H, Nielson R, Carruthers E, Diédhiou C, Ahmadou D, Soropogui B, Ruedas J, Peters K, Bartkowiak M, Magassouba N, Mboup S, Ben Amor Y, Connor JH, Weidemaier K. A point-of-care diagnostic for differentiating Ebola from endemic febrile diseases. Sci Transl Med. 2018 12 12; 10(471). PMID: 30541788.

    Read at: PubMed
  • Published on 11/22/2018

    Speranza E, Ruibal P, Port JR, Feng F, Burkhardt L, Grundhoff A, Günther S, Oestereich L, Hiscox JA, Connor JH, Muñoz-Fontela C. T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans. J Infect Dis. 2018 11 22; 218(suppl_5):S508-S518. PMID: 29986035.

    Read at: PubMed
  • Published on 11/22/2018

    Cross RW, Speranza E, Borisevich V, Widen SG, Wood TG, Shim RS, Adams RD, Gerhardt DM, Bennett RS, Honko AN, Johnson JC, Hensley LE, Geisbert TW, Connor JH. Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans. J Infect Dis. 2018 11 22; 218(suppl_5):S486-S495. PMID: 30476250.

    Read at: PubMed
  • Published on 9/26/2018

    Olsen ME, Cressey TN, Mühlberger E, Connor JH. Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression. J Virol. 2018 10 15; 92(20). PMID: 30045993.

    Read at: PubMed
  • Published on 9/12/2018

    Ruedas JB, Arnold CE, Palacios G, Connor JH. Growth-Adaptive Mutations in the Ebola Virus Makona Glycoprotein Alter Different Steps in the Virus Entry Pathway. J Virol. 2018 10 01; 92(19). PMID: 30021890.

    Read at: PubMed
  • Published on 6/5/2018

    Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH. Correction for Olsen et al., "Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication". MBio. 2018 06 05; 9(3). PMID: 29871921.

    Read at: PubMed
  • Published on 5/22/2018

    Schultz MJ, Tan AL, Gray CN, Isern S, Michael SF, Frydman HM, Connor JH. Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication. MBio. 2018 05 22; 9(3). PMID: 29789369.

    Read at: PubMed

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