Flora Sam, MD

Associate Professor, Medicine

Flora Sam
(617) 638-8060
88 E. Newton St Newton Pavilion

Biography

Dr. Sam is a clinical heart failure cardiologist and a physician-scientist. She is recognized NIH funded, independent investigator in cardiac myocyte biology and in mechanisms of myocardial remodeling in cardiomyopathy, both in humans and animal models. She is a recognized expert in diastolic heart failure (HFpEF) and systolic heart failure (HFrEF). .

The Sam lab is focused on three major areas of investigation:
1) Pro-inflammatory and pro-fibrotic mechanisms that mediate cardiac remodeling in heart failure and hypertension.
2) Investigating the relationship between matrix markers and heart failure in humans with cardiac amyloid and scleroderma.
3) Investigating cross talk between adipocyte-derived factors, myokines and cardiokines in heart failure.

Other Positions

  • Active Staff Hospital Privileges, Medicine, Boston Medical Center

Education

  • University of Witwatersrand , MBBCh

Publications

  • Published on 4/22/2015

    Tahir U, Sam F. Withdrawal of heart failure medications in peripartum cardiomyopathy after myocardial recovery. Int J Cardiol. 2015 Jul 1; 190:212-3.

    Read at: PubMed
  • Published on 2/24/2015

    Tahir U, Doros G, Sam F. Delayed myocardial recovery in peripartum cardiomyopathy. Int J Cardiol. 2015 Apr 1; 184:310-2.

    Read at: PubMed
  • Published on 12/15/2014

    Brogan A, Ding Y, Pimentel DR, Sam F. Non-invasive imaging for cardiac amyloidosis - delaying the obvious? Int J Cardiol. 2014 Dec 15; 177(2):e87-9.

    Read at: PubMed
  • Published on 8/22/2014

    Tanaka K, Wilson RM, Essick EE, Duffen JL, Scherer PE, Ouchi N, Sam F. Effects of adiponectin on calcium-handling proteins in heart failure with preserved ejection fraction. Circ Heart Fail. 2014 Nov; 7(6):976-85.

    Read at: PubMed
  • Published on 11/23/2013

    Quiroz R, Doros G, Shaw P, Liang CS, Gauthier DF, Sam F. Comparison of characteristics and outcomes of patients with heart failure preserved ejection fraction versus reduced left ventricular ejection fraction in an urban cohort. Am J Cardiol. 2014 Feb 15; 113(4):691-6.

    Read at: PubMed
  • Published on 7/19/2013

    Essick EE, Wilson RM, Pimentel DR, Shimano M, Baid S, Ouchi N, Sam F. Adiponectin modulates oxidative stress-induced autophagy in cardiomyocytes. PLoS One. 2013; 8(7):e68697.

    Read at: PubMed
  • Published on 6/5/2013

    Yancy CW, Jessup M, Bozkurt B, Masoudi FA, Butler J, McBride PE, Casey DE, McMurray JJ, Drazner MH, Mitchell JE, Fonarow GC, Peterson PN, Geraci SA, Horwich T, Januzzi JL, Johnson MR, Kasper EK, Levy WC, Riegel B, Sam F, Stevenson LW, Tang WH, Tsai EJ, Wilkoff BL. 2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013 Jun 5.

    Read at: PubMed
  • Published on 6/5/2013

    Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, Johnson MR, Kasper EK, Levy WC, Masoudi FA, McBride PE, McMurray JJ, Mitchell JE, Peterson PN, Riegel B, Sam F, Stevenson LW, Tang WH, Tsai EJ, Wilkoff BL. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013 Oct 15; 62(16):e147-239.

    Read at: PubMed
  • Published on 6/5/2013

    2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013 Oct 15; 128(16):e240-327.

    Read at: PubMed
  • Published on 6/5/2013

    Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Drazner MH, Fonarow GC, Geraci SA, Horwich T, Januzzi JL, Johnson MR, Kasper EK, Levy WC, Masoudi FA, McBride PE, McMurray JJ, Mitchell JE, Peterson PN, Riegel B, Sam F, Stevenson LW, Tang WH, Tsai EJ, Wilkoff BL. 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013 Oct 15; 128(16):1810-52.

    Read at: PubMed

View 45 more publications: View full profile at BUMC

View all profiles