David Hing-Kwei Chui, MD

Professor, Medicine

(617) 414-1018
75 E. Newton St Evans Building

Biography

Expertise includes: Globin gene mutations; Hemoglobin diseases; Thalassmeias; and Regulation of fetal hemoglobin expression.

Other Positions

  • Professor, Pathology & Laboratory Medicine, Boston University School of Medicine
  • Active Staff Hospital Privileges, Pathology & Laboratory Medicine, Boston Medical Center

Education

  • McGill University, MD
  • University of Maryland, BSc

Publications

  • Published on 4/28/2017

    Cancio MI, Aygun B, Chui DHK, Rothman JA, Scott JP, Estepp JH, Hankins JS. The clinical severity of hemoglobin S/Black (A ?dß)0 -thalassemia. Pediatr Blood Cancer. 2017 Nov; 64(11). PMID: 28453928.

    Read at: PubMed
  • Published on 2/27/2017

    Jiang Z, Luo HY, Farrell JJ, Zhang Z, Schulz VP, Albarawi D, Steinberg MH, Al-Allawi NA, Gallagher PG, Forget BG, Chui DH. A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes. Br J Haematol. 2017 Feb 27. PMID: 28240767.

    Read at: PubMed
  • Published on 4/28/2016

    Luo HY, Chui DH. Diverse hematological phenotypes of ß-thalassemia carriers. Ann N Y Acad Sci. 2016 Mar; 1368(1):49-55. PMID: 27123947.

    Read at: PubMed
  • Published on 1/13/2016

    Jiang Z, Luo HY, Huang S, Farrell JJ, Davis L, Théberge R, Benson KA, Riolueang S, Viprakasit V, Al-Allawi NA, Ünal S, Gümrük F, Akar N, Basak AN, Osorio L, Badens C, Pissard S, Joly P, Campbell AD, Gallagher PG, Steinberg MH, Forget BG, Chui DH. The genetic basis of asymptomatic codon 8 frame-shift (HBB:c25_26delAA) ß(0) -thalassaemia homozygotes. Br J Haematol. 2016 Mar; 172(6):958-65. PMID: 26771086.

    Read at: PubMed
  • Published on 9/15/2015

    Akinbami AO, Campbell AD, Han ZJ, Luo HY, Chui DH, Steinberg MH. Hereditary Persistence of Fetal Hemoglobin Caused by Single Nucleotide Promoter Mutations in Sickle Cell Trait and Hb SC Disease. Hemoglobin. 2016; 40(1):64-5. PMID: 26372199.

    Read at: PubMed
  • Published on 10/27/2014

    Edward HL, Pisani LA, Rodriguez-Romero WE, Chaves-Villalobos J, Garcia-Quesada J, Harris NS, Luo HY, Steinberg MH, Forget BG, Chui DH. Hb Youngstown [ß101(G3)Glu???Ala; HBB: c.305A > C]: An unstable hemoglobin variant causing severe hemolytic anemia. Hemoglobin. 2014; 38(6):381-4. PMID: 25347256.

    Read at: PubMed
  • Published on 8/4/2014

    Griffin PJ, Sebastiani P, Edward H, Baldwin CT, Gladwin MT, Gordeuk VR, Chui DH, Steinberg MH. The genetics of hemoglobin A2 regulation in sickle cell anemia. Am J Hematol. 2014 Nov; 89(11):1019-23. PMID: 25042611.

    Read at: PubMed
  • Published on 11/13/2013

    Alsultan A, Alabdulaali MK, Griffin PJ, Alsuliman AM, Ghabbour HA, Sebastiani P, Albuali WH, Al-Ali AK, Chui DH, Steinberg MH. Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign. Br J Haematol. 2014 Feb; 164(4):597-604. PMID: 24224700.

    Read at: PubMed
  • Published on 11/12/2013

    Steinberg MH, Chui DH, Dover GJ, Sebastiani P, Alsultan A. Fetal hemoglobin in sickle cell anemia: a glass half full? Blood. 2014 Jan 23; 123(4):481-5. PMID: 24222332.

    Read at: PubMed
  • Published on 6/15/2013

    Croteau SE, Luo HY, Lehmann LE, Chui DH, Neufeld EJ. Novel dominant ß-thalassemia: Hb Boston-Kuwait [codon 139/140(+T)]. Pediatr Blood Cancer. 2013 Oct; 60(10):E131-4. PMID: 23776097.

    Read at: PubMed

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