Two Departmental Seminars – Thurs Sep 17 and Fri Sep 18

September 1st, 2015 in Spotlight

September 17th – THURSDAY @ 1:00

“Peptide-based Stx Neutralizers for Treatment of STEC Infections”

Dr. Kiyotaka Nishikawa

Professor, Faculty of Life and Medical Sciences

Doshisha University; Kyoto, Japan

Please note change of date and time.



September 18th – Friday @ 2:00

“Growth Factor Influence on Macrophages in Infection and Metabolism”

Filip Swirski, PhD

Associate Professor, Center for Systems Biology
Massachusetts General Hospital; Harvard Medical School

Refreshments at 1:45 p.m.


670 Albany Street – Lobby Level #107/108

Program Director, Barbara Slack, PhD
Program Coordinator: Debra Kiley, 414-7914

July 2015

August 5th, 2015 in Uncategorized

Pathology & Laboratory Medicine News Items – July 2015

  • Announcements:
    • A manuscript describing the study from Panchenko Lab was accepted for publication by Cell Cycle without any revision or resubmission. The authors discovered an unexpected role of the component of the histone acetyl trasferase complex, JADE1, in cytokinesis – which is the least described but the most crucial phase of the epithelial cell cycle progression. The study defined JADE1 protein as novel factor of tissue regeneration and a potential player in cancer pathogenesis. By the choice of the Editor-in-Chief this study will be featured in the “News & Views” of the Journal; “The novel function of JADE1 in cytokinesis of epithelial cells” by N.S. Siriwardana, R.D. Meyer, and M.V. Panchenko
    • David Sherr and his team just had a R01 score in the 1 percentile. The is the grant, with George Murphy co-PI, which is focused on manipulating AHR activity in differentiating iPSC and resulting in production of unlimited numbers of human red blood cells
    • After a long and distinguished career, Tom Christensen has retired! Here are some photos of the luncheon held in his honor:
    • Cake.cwvDm9asA_Lw9YsGTQNy8vW7ZxwCAVZZH6V
    • Family Looking On. cwvDm9asA_Lw9YsGTQNy8vW7Zxw
      Young Visitors.cwvDm9asA_Lw9YsGTQNy8vW7ZxwCA5WHC2I
    • Nancy S. Miller, MD presented the Special Session lecture, “Laboratory considerations in an era of improved microbial identification”, at the 4th International Conference and Exhibition on Pathology, July 13-15, 2015 in New Orleans, Louisiana
    • Dr. Anita Deshpande successfully passed both the Anatomic Pathology and Clinical Pathology portions of the board, BRAVO!
  • Publications ACCEPTED:
    • S. Siriwardana, R.D. Meyer, and M.V. Panchenko. “The novel function of JADE1 in cytokinesis of epithelial cells” Cell Cycle 
    • Brooks CR, Yeung MY, Chen H, Henderson JM, Ichimura T, Bonventre JV.  KIM-1/TIM-1-mediated phagocytosis links ATG5/ULK1 dependent clearance of apoptotic cells to antigen presentation.  EMBO J.  ACCEPTED FOR PUBLICATION
    • Ip, B, Cilfone, N, Belkina, AC, DeFuria, J, Jagannathan-Bogdan, M, Zhu, M, Kuchibhatla, R, McDonnell, ME, Xiao, Q, Kepler, TB, Apovian, CM, Lauffenburger, DA, and Nikolajczyk, BS. 2015. Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFa production. Obesity. (In Press)
  • Publications PUBLISHED:




July 8 2015 Faculty meeting information

July 8th, 2015 in Faculty Highlights


Faculty Meeting Agenda, Wednesday, July 8 2015, Pathology & Laboratory Medicine

12:00PM– 1:00PM Location 107/108, 670 Albany (first floor)


Noon – 12:10 (10 minutes) Changes resulting from surveys/town hall meetings – Daniel Remick

The faculty participated in two extensive surveys, several individual meetings and a town hall meeting to discuss multiple issues. Most of our meeting today will focus the future and recent initiatives, with presentations by the faculty leading these efforts. Since we are talking about moving forward, it is appropriate to briefly review the accomplishments and changes that have been made:

  • Finances: The monthly financial statements are being forwarded to all faculty. Twice per year there will be a summary overview of the Department’s financial status.
  • Promotions: The issue about promotions has been discussed during the annual evaluations, and the information from the medical school’s promotions committee has been forwarded. If there are additional questions please arrange a time to meet with me individually.
  • Compensation: The Department voted on a compensation plan, and effective July 1, 2015, virtually all faculty will be in compliance. More specifically, the salary and bonus will be result in the faculty being paid at the median compensation within seven years of initial appointment or promotion.
  • Bonus: The Mallory practice plan has completed the year in a positive financial status. Bonuses will be paid in September after the financial statements have been audited. Unfortunately, there are no funds available to provide a bonus this year to the non-FPF faculty.
  • Department Governance: Each committee specifically includes at least one Assistant Professor.
  • Additional faculty member: Our most recent recruit has decided to stay in her current position, and the other top two candidates accepted jobs back in February. As part of the strategic planning process we will review the Department’s needs and plan accordingly.
  • Communication: Several steps have been taken to improve communications
    • Reiteration of the University’s expectations for promotion
    • Forwarding financial information about the Department and the Hospital on a monthly basis
    • Bi-annual aggregated financial information
    • Additional one-on-one meetings for individualized feedback
    • Clear compensation policy tied to the academic mission of the Department
    • We should determine the format to provide feedback from students and residents?


12:10 – 12:35 (25 minutes) Education initiatives

  • PA 810 The Business of Science – Daniel Remick for Deborah Stearns-Kurosawa
  • PA 910 Human Biospecimens for Research – Ivanna Delalle
  • Master’s of Arts in Pathology – Chris Andry
  • Offsite Immunology course – Jacqueline Sharon
  • University of Damman – David Kindelberger, Joel Henderson, Nancy Miller
  • Residency education – Joel Henderson


12:35 – 12:40 Status of outreach efforts – Daniel Remick

Lemuel Shattuck Hospital – Huihong Xu

Weymouth endoscopy – Michael O’Brien

Brigham and Women’s – Ivana Delalle

Cyprus – to be determined


12:40 – 12:45 (5 minutes) Molecular testing revenue – Gail Whitney

With the departure of the Center for Human Genetics we made a decision to expand our molecular testing, rather than send out the specimens. From July 2014 – June 2015, there was a net loss of approximately $53,000.00. This loss was due to the pre-purchase of supplies and a delay in bringing a test on board. For the next year we anticipate that there will be a positive balance of $73,000.00. We are aggressively expanding our molecular testing to improve patient care by offering better service at the same price.


12:45 – 1:00 (15 minutes) Strategic planning – Daniel Remick



June 2015

July 2nd, 2015 in Uncategorized


Pathology & Laboratory Medicine News Items – June 2015


  • BMC “Be Exceptional” Awards 2015, which recognize outstanding BMC staff who demonstrate exceptional performance and dedication to fulfilling BMC’s mission and four QUEST goals: Quality, Efficiency, Satisfaction, and Total Revenue. “Chosen by a committee made up of leaders from around the hospital, they were selected for their exceptional performance, initiative and teamwork, and for embodying our RESPECT behavioral attributes. These staffers reflect BMC on its best day, every day. Congratulations to the following individuals and teams!” Two members of the Department of Pathology and Laboratory Medicine are among this year’s recipients which were awarded on June 17th in Hiebert Lounge.:
    • Sherri Dagger, one of our Pathology Histotechnologist, for her exceptional performance and dedication to fulfilling BMC’s mission and QUEST goals
    • Neil O’Neil, Laboratory Administration Operations, “this appropriately recognizes his outstanding service to BMC”
  • Shinichiro Kurosawa has accepted an invitation to serve as a member of the Host Interactions with Bacterial Pathogens Study Section at NIH at the Center for Scientific Review, for the term beginning July 01, 2015 and ending June 30, 2019
  • Daniel Remick was in Brazil last month for the 12th Annual Forum on Sepsis at the Latin-American Institute for Sepsis in Sao Paulo, Brazil:
    • Remick gave the Keynote Address at the Forum; Pathophysiologic Mechanisms in Septic Shock
    • Remick also presented at the Thematic Session – Therapeutic Interventions; Do Inhibitory Immunoglobulins Decrease Pathogen Killing and Increase Sepsis Mortality
    • He spoke again at the Thematic Session, Special Situations in Sepsis; Brain Injury and Pneumonia Prevention
  • Nader Rahimi, PhD was awarded a R21 grant from NIH/NCI entitled “IGPR-1 in colon cancer chemotherapy”. The overall of goal of this research is to study the role of IGPR-1 in colon cancer and chemo treatment. IGPR-1 is a novel protein identified in the Rahimi laboratory. IGPR-1 represents a new class of cell surface receptors involved in cell-cell recognition and mediates tumor angiogenesis, a process by which new blood vessels are recruited to growing tumor.
  • Ivana Delalle just presented an abstract at the International Conference on “The long and the short of non-coding RNAs” in Greece, June 14-19, 2015.
  • Delalle also presented “Exosomal microRNAs as biomarkers for bipolar disorder and schizophrenia” Jason Choi1, Andre Fischer 2,3, Farahnaz Sananbenesi3, and Ivana Delalle1. 1Boston University School of Medicine, Boston, MA, USA, 2Goettingen University, Goettingen, Germany, 3German Center for Degenerative Diseases (DZNE), Goettingen, Germany.  



  • New Residents:
    • Entering PGY 1s

      • Israa Laklouk, MD   Laklouk
        • Relocating from San Francisco, CA
        • Graduated from University of Tripoli in 2008
      • Mahmoud Soliman, MD  Soliman
        • Relocating from Grand Forks, ND
        • Graduated from University of Cairo in 2004

    • Transferring PGY 2s
      • Lei Li, MD  Li
        • Transferring from residency at Saint Barnabas Medical Center
        • Graduated from Xuzhou Medical College – China in 2000
      • Ram Al-Sabti, MD   Ram Al-Sabti2

        • Transferring from residency at Case Western
        • Graduated from University of Baghdad in 2009
  • Kurosawa Lab:
    • Annalyn Brown is a STaRS summer student (Summer Training as Research Scholar) in our lab and her project is about how inflammation alters susceptibility of cells to bacterial toxins.  Specifically she’ll investigate whether activation of TLR4 increases Gb3 receptor expression for Shiga toxins on endothelial cells.  Annalyn is an undergraduate student at the University of the Virgin Islands and we’re pleased to have her in our lab this summer.
    • Evan Catudal is a Master’s student in the Pathology program with experience as a medical technologist.  His thesis project is a collaborative effort between the Kurosawa and Remick labs to identify contributions of coagulation pathways to enhanced survival of mice after mild traumatic brain injury and pneumoniahasis
    • Greg Hall is a licensed veterinarian in the PhD program with interests in animal model development and development of disease pathology.  He will be working in the Kurosawa Lab on animal models of thrombotic microangiopathy for his thesis project.  joined the Kurosawa Lab coming after his first year in the PIBS Program
  • Remick Lab:
    • Gina Ellsworth, a science/biology teacher at Haverhill High School is a summer intern with the American Association of Immunologists, where she is learning laboratory techniques in the Remick Lab to create a hands -on activity and curriculum of immunology.  This activity will be demonstrated at the National Association of Biology Teachers conference in November and the curriculum will be posted to the AAI website by Spring 2016. Gina is working with postdoc Evan Chiswick, PhD.
    • Alejandro Sanoja is a rising senior from the University of Florida. He is a member of the Summer Training as Research Scholars (STaRS) program at BU. Alejandro’s STaRS internship in the Remick Lab will be with Terry Hsieh, MD/PhD candidate and focuses on investigating immune priming in a mouse model
  • Summer Training as Research Scholars Program.
    • STaRS is designed to promote access to graduate education for talented undergraduates from minority groups traditionally underrepresented in the biomedical sciences:  African-American, Hispanic,  Native American/Native Alaskan, and Pacific Islander/Native Hawaiian.  STaRS is sponsored by the Division of Graduate Medical Sciences, a recognized leader in graduate education and biomedical research.
    • STaRS is a dynamic and focused program that is designed specifically for the enhancement of skills required for successful entrance and completion of a graduate program or an MD/PhD program in the biomedical sciences.
    • STaRS offers motivated and academically talented students a valuable opportunity to confirm a strong interest in doctoral studies particularly in the areas of heart, lung and blood research.


  • Castle Graduation Dinner Celebration 2015:


IMG_0045.All Residents



















Publications ACCEPTED:

  • Emad Arafa, Philip Bondzie, Kobra Rezazadeh, Rosana D Meyer, Edward Hartsough, Joel Henderson, John H. Schwartz, Vipul Chitalia, Nader Rahimi. TMIGD1 is a novel adhesion molecule that protects epithelial cells from oxidative cell injury. American Journal of Pathology, 2015 Emad Arafa & Philip Bondzie are co-primary authors




Dissertation Defense Seminar – Mostafa Belghasem – July 30

July 2nd, 2015 in Spotlight

BUSM Pathology & Laboratory Medicine


Dissertation Defense Seminar

Thursday, July 30th, 2015; 11:00 AM

670 Albany Street – Lobby Level #107/108


Mostafa Belghasem

PhD Candidate


Will defend his dissertation thesis:

Pathological and Molecular Profiling in

Hypertension-Induced Glomerular Injury”


Thursday, July 30th, 2015

11:00 AM

670 Albany Street – Lobby Level #107/108

Commencement 2015

June 2nd, 2015 in Spotlight

Commencement, May 15, 2015


Emad Arafa, MA

Philip Bondzie, PhD

Patricia Chun, MA

Zach Hunter, PhD

Clarissa Koch, PhD

Caitlin Leibowitz Parello, PhD

Jordan Shafran, MA

Nick Woolf, MD/MA

For updates on their new positions, please visit our Departmental Graduates page.


RahimiandCrew.graduation ceremony-2015




May 2015

June 2nd, 2015 in Uncategorized

Pathology & Laboratory Medicine News Items – May 2015


  • LAB WEEK was April 20-24 this year, the theme was “was “Not all Heroes Wear Capes, Some Wear Lab Coats!” Events for the week included: a scavenger hunt, door decorating contest, which Chemistry won, for a departmental pizza party, we had games, and we collected $213 for the Cancer Center by allowing employees to wear jeans. We also handed out tumblers as lab week gifts




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SuperheroMarthaRodgers.IMG_5647 (2)


  • Huihong Xu was invited to give a cytology lecture “GI Interesting Cytology Cases” for the pathology residents at Brigham & Women’s Hospital on May 12th, 2015.
  • Congratulations; Lee Quinton has been promoted to Associate Professor of Medicine and Pathology & Laboratory Medicine
  • Last year Mostafa Belghasem, PhD candidate taught PS701 Immunology/Pathology lectures; these lectures were well-received by the Physician Assistance students and accordingly, he has been invited by the course directors to teach this year as well
  • Carmen D. Sarita –Reyes attended, as a member, the National Board of Dental Examiners Microbiology-Pathology Test Construction Committee Meeting  from May 11th – 15th 2015 in Chicago, Illinois
  • Debbie Stearns-Kurosawa, PhD was an invited featured speaker at the 2015 American Society for Apheresis Annual Conference May 6 – 9 in San Antonio, Texas.  Her talk was entitled: The Pathophysiology of E.coli-Mediated Hemolytic Uremic Syndrome
  • Mostafa Belghasem, PhD candidate was invited by the Boston University Renal Section to talk about his thesis work. The lecture Mostafa presented was: Pathological and Molecular Profiling in Hypertension-induced Glomerular Injury on April 30, 2015
  • A collaborative project between the Kurosawa Lab and Drs. Monica Schaller and Johanna Kremer Hovinga from the University Clinic of Hematology, Central Hematology Laboratory and Department of Clinical Research, University Hospital Berne, Berne, Switzerland was accepted as a poster presentation for the International Society of Thrombosis and Haemostasis (ISTH) meeting in Toronto, Canada (June 20-25).  The abstract is entitled:  ANTI-IDIOTYPIC DARPINS RESTORE ADAMTS13 ACTIVITY IN BABOONS CHALLENGED WITH HUMAN MONOCLONAL ANTIBODIES: FIRST STEP TOWARDS AN ANIMAL MODEL FOR HUMAN ACQUIRED TTP
  • Dave Sherr, PhD and his Lab has received yet another $50k from Avon for breast cancer
  • BRAVO is in order:
    • Chris Andry has been reappointed as Chair of Boston University’s Safety Committee
    • Abigail Brown has been reappointed as a Voting Member of Boston University’s Safety Committee
    • Shinichiro Kurosawa has been reappointed as a Voting Member of Boston University’s Safety Committee
    • Liz Duffy has been newly appointed as a Voting Member of Boston University’s Safety Committee
    • Dave Sherr, PhD and his Lab has received yet another $50k from Avon for breast cancer
    • Commencement, May 15, 2015; CONGRATULATIONS GRADUATES:
      • Emad Arafa, MA
      • Philip Bondzie, PhD
      • Patricia Chun, MA
      • Zach Hunter, PhD
      • Clarissa Koch, PhD
      • Caitlin Leibowitz Parello, PhD
      • Jordan Shafran, MA
      • Nick Woolf, MD/MA


RahimiandCrew.graduation ceremony-2015




    • Publications PUBLISHED:
      • Malek A, Lee J.C. Extranodal marginal zone lymphoma of mucosa associated lymphoid tissue arising in the pleura. Annals of Pathology and Laboratory Medicine. Vol 2, No 2 (2015)
    • Publications ACCEPTED:
      • Mathew H, Dittus C, Malek A, Negroiu A. Howell-Jolly Bodies on Peripheral Smear Leading to Diagnosis of Congenital Hyposplenism in a Patient with Septic Shock. Clinical Case Report
      • Srimathi Srinivasan, Vipul Chitalia, Rosana D Meyer, Edward Hartsough, Manisha Mehta, Itrat Harrold, Nicole Anderson, Hui Feng, Lois E.H. Smith, Yan Jiang, Catherine E. Costello, Nader Rahimi. Hypoxia-induced expression of Phosducin like 3 regulates expression of VEGFR-2 and promotes angiogenesis. Angiogenesis, 2015.
      • Sowmya Shivanna, Kumaran Kolandaivelu, Moshe Shashar, Mostafa Belghasem, Laith Al-Rabadi, Mercedes Balcells, Anqi Zheng, Janice Weinberg, Jean Francis, Michael P. Pollastri, Elazer R. Edelman, David H. Sherr, and Vipul C. Chitalia. “The Aryl Hydrocarbon Receptor is a Critical Regulator of Tissue Factor Stability and an Antithrombotic Target in Uremia”. Accepted for publication by the Journal of the American Society of Nephrology. May 2015.



April 2015

May 4th, 2015 in Uncategorized

Pathology & Laboratory Medicine News Items


  • Stephanie Adams, OD/PhD Student and Ivana Delalle have an abstract that has been accepted for a platform presentation at the American Association of Neuropathologists meeting in June in Denver, CO.; “BIN1 Expression In Human Hippocampus During Alzheimer’s Disease Progression,” Authors: Stephanie Adams1, Kathy Tilton1, Sudha Seshadri2, Ivana Delalle1.
  • As part of the new collaboration between Boston University and the University of Damman, Saudi Arabia, Daniel Remick gave two presentations in April in Saudi Arabia :
    • Keynote Address, University of Damman, Saudi Arabia, 1st Annual Scientific Research Update – Traumatic Brain Injury Augments Pulmonary Host Responses to Bacteria: Molecules and Mechanisms
    • Specialized Workshop, King Fahd Hospital University of Damman, Saudi Arabia, Immunopathology of Sepsis – 2015
  • Dr. Remick served as an ad hoc member of the Board of Scientific Review for the National Institutes of Arthritis, Musculoskeletal and Skin Diseases at the National Institutes of Health.
  • Barbara Slack, Pathology Department Russek Awards Committee Member, is pleased to announce that this year’s Russek Award recipients in the Department of Pathology and Laboratory Medicine are:
    • First Prize Recipient – Jacquelyn Sikora Hanson (Advisor: Lawreen Connors); Jacquelyn presented her talk on May 1st entitled; “The transthyretin gene variant G6S may be protective in wild-type transthyretin amyloidosis.”
    • Second Prize Co-Recipients – Caitlin Miller (Advisor: Suryaram Gummuluru) & Nicole Stauffer (Advisor: Joseph P. Mizgerd)
    • Congratulations to the award winners, and thank you to everyone who submitted abstracts for the poster session. Russek Day was held on May 1st in the Hiebert Lounge (L building, 14th floor). The keynote speaker this year was Dr. David M. Livingston, Emil Frei Professor of Medicine at Harvard Medical School. Posters were available for viewing throughout the day, and slide presentations by the first prize winners took place in the afternoon. More information about this event can be found at the link (
  • David Sherr, PhD, MD/PHD student, Olga Novikov, won the School of Public Health’s Dean’s Award. See link below.
  • Congratulations are in order for Emad Arafa and Jordan Shafran, both graduating Masters students in Nader Rahimi’s Lab. Emad and Jordan have been accepted in BU’s PIBS PhD Program; Bravo!
  • Nisma Mujahid, one of our MD/PhD student has been awarded the Canadian Institutes of Health Research Doctoral Foreign Study Award
  • The department’s biobanking team were represented by Chris Andry, Liz Duffy and Cheryl Spencer at a two day summation meeting for the cancer Human Biobank (caHUB) and Ethical, Legal and Social Implications (ELSI) program at the National Cancer Institute in Bethesda, MD on April 22nd. All four biospecimen source sites involved in the pre-analytic variables study were represented as well as the analytics teams from around the country.  The BMC team presented data regarding biospecimen collection in the pre-analytic variables study as well as on the ELSI enrollment and consent surveys.
    • Analytics data on immunohistochemistry and in situ staining, proteomics and genomics are expected by late Fall.  The ELSI data was synthesized and analyzed by Dr. Teddy Warner, University of New Mexico with very interesting preliminary results
    • BMC’s biobanking efforts were recognized by the NCI leadership, particularly in the areas of quality and collaboration. All pathology faculty and residents were acknowledged for their contributions to the project

Publications PUBLISHED:

  • Eladio Rodriguez-Diaz PhD, Qin Huang MD, Sandra R. Cerda MD, Michael J. O’Brien MD, Irving J. Bigio PhD, Satish K. Singh MD; Endoscopic histological assessment of colonic polyps by using elastic scattering spectroscopy. Gastrointestinal EndoscopyJjournal. March 2015, Vol.81(3):539547
  • “Systems Biology of Cancer” edited by Sam Thiagalingam, PhD
    • A book edited by Dr. Sam Thiagalingam entitled “Systems Biology of Cancer” was released by the publisher Cambridge University Press on April 9, 2015. It provides a comprehensive account of the current state of the knowledge and a road map to formulate a blueprint for the biological basis of cancer. The emphasis of the book is on the biology with minimal mathematical derivations and computational methods which are still evolving to meet the unprecedented amount of data produced with high-throughput experimentation methods that are continuing to be developed.
    • Readers will be able to get a realistic view of what is known and remaining to be uncovered in the chapters presented by international experts on the aberrations in the fundamental biological processes, deregulation of major signaling networks, alterations in major cancers and the strategies for using the scientific knowledge for effective diagnosis, prognosis and drug discovery to improve public health. This will serve as a useful text on cancer suitable for students and researchers in all stages of their careers including the undergraduates. The contents are most suitable and highly recommended for graduate students, medical residents and fellows and experienced researchers. This landmark volume consists of a collection of 32 chapters with contributions from more than 75 international experts which includes 8 chapters by Boston University faculty and trainees. At this time the publisher is providing a 20% discount (see Flyer). Thiagalingam-Flyer-SystemsBiologyof Cancer-2015
    • This link allows you to look at the first few pages of the book in kindle:
  • Witthaus MW, Nipa F, Yang JH, Li Y, Lerner LB, Azadzoi KM. Bladder Oxidative Stress in Sleep Apnea Contributes to Detrusor Instability and Nocturia. J Urol. 2015 May;19 (5):1692-9. PMID: 25463994

March 2015

April 6th, 2015 in Uncategorized

Pathology & Laboratory Medicine News Items


  • 104th USCAP Meeting, Boston, MA, March 21-27 2015
    • Cathryn Byrne-Dugan, MD had her abstract accepted:Podocyte Infolding Glomerulopathy – Occurrence of the Disease Entity in the United States, and the Potential Role of an Autoantibody;” Authors:Cathryn J Byrne-Dugan, Pavel Kopach, Laurence H Beck, Vanesa Bijol, Monika Pilichowska, Helmut G Rennke, Masha Bilic
    • Meera Mahalingam will be the Chair/Moderator of “Neoplastic Dermatopathology – Clues and Confounders.” Topic was selected to highlight histopathologically confounding issues in cutaneous neoplasms. Neoplasms selected encompass a spectrum of lineage-unrelated tumors that are commonly encountered some perhaps more than others by a general pathologist both in private practice and in an academic setting. Each speaker will begin with an initial description of the entity and conclude with clues and confounding issues relevant to the entity discussed
    • Qing Zhao, Shi Yang, Cecilia Ponchiardi, and Michael O’Brien had their abstract BRAF/KRAS Mutation, MSI/MSS Status and Tumor Budding in Colorectal Carcinoma” at the Poster Session on Tuesday, March 24th
    •   “Resident Shiva Khoobyari, MD enjoying a Poster at this year’s USCAP in Boston”
  • Congratulations to Karen Quillen on her recent promotion to full professor. There is a nice article in BU today about her advancement.
  • Daniel Remick, M.D., has been selected to be a Guest Editor for the Journal of Leukocyte Biology beginning February 2015. Dr. Remick will serve as the Editor for manuscripts solicited from the 2014 joint annual meeting of the Society for Leukocyte Biology and the International Innate Immune and Endotoxin Society.
  • On March 9th 2015 in Boston, MA. Carmen Sarita-Reyes presented at the 2015 Annual Session and Exhibition of the American Dental Education Association (ADEA) a Chair of the ADEA Board of Directors Symposium. The presentation was titled: “IGNITING MINDS THROUGH STUDENT SELF-DIRECTED GROUP LEARNING: Integrated  Problem Sessions (IPS.) Chair of the ADEA Board of Directors Symposium;” Cataldo W. Leone, DMD, DMSc, Carol T. Walsh, MA, PhD, Carmen D. Sarita-Reyes, MD, Monica A. Pessina, MEd, PhD, and Elizabeth R. Whitney, MSPT, PhD
  • Resident Reyhan Gedik, MD volunteers for a non-profit organization called White Tulip Foundation. We organize monthly seminars (called Boston Medical forum ) to share our experiences as medical doctors and scientists. In March they invited David Kindelberger to give a talk about “Circulating Tumor Cells; New Tools for Personalized Medicine” and he kindly accepted. Keep an eye out for other interesting topics.
  • Clarissa Koch, PhD, Connors Lab, successfully defended her thesis “Characterizing the Effect of Transthyretin Amyloid on the Heart” on Monday, March 16th
  • “Clarissa Koch, PhD Candidate and her PI Lawreen Connors, about to give her Defense” and “Dr. Koch’s Celebration”
  • MATCH DAY 2015:
    • Bravo to MD/PhD Graduate David Stepien for successfully being accepted into his First Choice in this year’s Match; Dave will be taking up residence in the University of Michigan Hospital Integrated Plastic and Reconstructive Surgery Residency Program
    • Hooray to 2011 Masters Degree Graduate Nik Bajaj for also getting into his First Choice in this year’s Match; Nik will begin his residency in the University of Illinois – COM – Chicago Neurology Residency Program
  • Kevin Chandler, PhD, a postdoctoral fellow working jointly in the Dr. Cathy Costello and Nader Rahimi laboratories was awarded a three year postdoctoral fellowship from the NIH. The goal of the project is to map the glycosylation of VEGFR-2 and the role of this posttranslational modification in the angiogenic signaling of VEGFR-2
  • David Sherr’s graduate student, Liz Stanford, was selected to be the GMS commencement student speaker
  • Barb Nikolajczyk, PhD is an invited speaker in March 2015 for:
    • Experimental Biology, Diet and Immunometabolism Symposium, Boston, MA, Lymphocyte function in human type 2 diabetes, 2015
    • Immunology Microbiology Program Spring Seminar Series, University of Massachusetts Medical School, Inflammation in human type 2 diabetes, 2015
    • Beth Israel Medical Center,  Inflammation in human type 2 diabetes, 2015
  • Carol Cohen will be presenting at the AATB Quality and Donor Suitability Workshop in Atlanta, Georgia on April 20th. Susan Sharpe MS, MT(ASCP), SBB, CTBS who is the Supervisor of the Tissue and Transfusion Service at Northside Hospital in Atlanta and Carol will be presenting on the FDA’s new ruling that requires medical devices to have unique device identifiers
  • Lawreen Connors, PhD was invited to speak at the EB/ASIP meeting here in Boston on March 31st; the title of her presentation was “The Translational Science of Transthyretin-associated Cardiomyopathies.”
  • Here’s a link to an article in the Chicago Tribune in which David Sherr is quoted/featured:
  • Remick was recently notified that graduate student, Ms. Erika Langley, was chosen this semester as a Teaching as Research Fellow. As a winner of this fellowship, she will receive an award of $1,000 and partake in a seminar in teaching as research. Teaching-as-Research involves the deliberate, systematic, and reflective use of research methods to develop and implement teaching practices that advance the learning experiences and outcomes of students and teachers. Erika will be in the TAR seminar this spring, and implement a project in a classroom in the summer or fall. Erika’s TAR project has the working title: Improving scientific literacy in undergraduates; she has the support of her faculty advisor for the project Prof. Paul Lipton and her research advisor Prof. Alpaslan Dedeoglu.

Publications ACCEPTED:

  • Goldberg, L.J., E. Wise, N. S. Miller. White piedra in a northern climate caused by Trichosporon inkin: A report of two cases. Item of correspondence. Accepted for publication, March 7, 2015. British Journal of Dermatology
  • Chad L Mayer, Caitlin S.L. Parello, Benjamin C Lee, Kiyoshi Itagaki, Shinichiro Kurosawa, DJ Stearns-Kurosawa. “Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga toxins and Host Damage-Associated Molecular Patterns”  Frontiers in Immunology, section Microbial Immunology.

Publications PUBLISHED:

  • Tagne, J.B., Mohtar, O.R., Campbell, J.D., Lakshminarayanan, M., Huang, J., Hinds, A.C., Lu, J., Ramirez, M.I. (2015) Transcription factor and microRNA interactions in lung cells: an inhibitory link between NK2 homeobox 1, miR-200c and the developmental and oncogenic factors Nfib and Myb Res. 16:22 PMC4335692
  • Rai A, Nimeh T, Sood A, Thirumavalavan N, Thurmond PE, Azadzoi KM, Lerner LB. Could nocturia be an indicator of an undiagnosed sleep disorder in male veterans? 2015 Mar;85(3):641-7. PMID: 25733279
  • Lei X, Liu C, Azadzoi KM, Li C, Lu F, Xiang A, Sun J, Guo Y, Zhao Q, Yan Z, Yang J,; A novel IgM-H-ficolin complement pathway to attack allogenic cancer cells in vitro. Sci Rep. 2015 Jan 16;5:7824. PMID: 25592840
  • Poutahidis, T., Varian, B. J., Levkovich, T., Lakritz, J. R., Mirabal, S., Kwok, C., & Erdman, S. E. (2015). Dietary microbes modulate transgenerational cancer risk. Cancer research, canres-2732       (BJ Varian is one of our Masters Students; this is with his MIT affiliation)
  • Shivanna S, Harrold I, Shashar M, Meyer R, Kiang C, Francis J, Zhao Q, Feng H, Edelman ER, Rahimi N, Chitalia VC. c-Cbl regulates nuclear β-catenin and angiogenesis through its Wnt-mediated phosphorylation. J Biol Chem. 2015 Mar 17J Biol Chem
  • Melody P. Lun, Matthew B. Johnson, Kevin G. Broadbelt, Momoko Watanabe, Young-jin Kang, Kevin F. Chau,Mark W. Springel, Alexandra Malesz, André M.M. Sousa, Mihovil Pletikos, Tais Adelita, Monica L. Calicchio,Yong Zhang, Michael J. Holtzman, Hart G.W. Lidov, Nenad Sestan, Hanno Steen, Edwin S. Monuki, and Maria K. Lehtinen. Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production. The Journal of Neuroscience 25 March 2015, 35(12): 4903-4916
  • Vanesa Bijol, Cathryn J. Byrne-Dugan, and Melanie P. Hoenig. Medical student web-based formative assessment tool for renal pathology. Medical Education Online, Volume 20, 2015;

Congratulations to Dr. Clarissa Koch

March 31st, 2015 in Student Spotlight

clarissa BU pathology website photo


Clarissa Koch, PhD, Connors Lab, successfully defended her thesis Characterizing the Effect of Transthyretin Amyloid on the Hearton Monday, March 16th