Pathology & Laboratory Medicine News Items – February/March 2017

April 4th, 2017 in Uncategorized

Pathology & Laboratory Medicine News Items – February/March 2017

Announcements:

  • Our Resident, Israa Laklouk, MD had the following abstract ” Diagnostic Implication of ThyroSeq Sequencing Assay on Thyroid Nodules with FNA Cytology Diagnosis of Bethesda III: Atypia of Undetermined Significance versus Follicular Lesion of Undetermined Significance ” authors: Israa Laklouk, Mahmoud L Soliman, Dhay Kamel, Huihong Xu, Sandra Cerda; selected for a Poster Presentation  at the United States & Canadian Academy of Pathology’s (USCAP) 106th Annual Meeting, March 4 – 10, 2017 in San Antonio, Texas  http://viewer.zmags.com/publication/84c2f7ae#/84c2f7ae/10
  • IsraaLakloud.Poster.USCAP2017-395-IL
  • IsraaLakloudandPoster.USCAP2017.IMG_3527
    • Lawreen H. Connors, PhD and Frederick L. Ruberg, MD presented “Transthyretin-associated (ATTR) cardiomyopathy: A not uncommon, rare disease” at BUSM Department of Medicine Medical Grand Rounds on Feb. 17, 2017 https://echo360.bu.edu:8443/ess/echo/presentation/66b063a7-a6f2-4ef9-8957-81e40ec68bb3
    • Carolina Lyon de Ana, a current Masters student in Dr. Susan Winandy’s Lab and Bo Shao, a technician with Dr. Maria Panchenko’s Lab were both accepted into BU’s PhD PIBS Program! Congratulations!!
    • Dr. Ivana Delalle News:
      • On March 24 Dr. Delalle gave an invited lecture at the Croatian Institute for Brain Research (CIBR) on “The brain expression of novel genes implicated in AD and low hippocampal volume”
      • She also presented her group’s latest work at AD/PD International Meeting in Vienna, March 29 – April 2: “Protein expression of low hippocampal volume- associated risk allele candidate MSRB3 in AD” by Stephanie L Adams1, Laurent Benayoun1, Jayandra J. Himali­­2,3, Kathy Tilton1,  Sudha Seshadri2,3, and Ivana Delalle1,31Pathology, Boston University School of Medicine; 2Framingham Heart Study, Boston University School of Public Health; 3Neurology, Boston University School of Medicine
      • Dr. Delalle has also been invited to give a talk at the 3rd Annual Next Generation Sequencing & Single Cell Analysis Congress, scheduled for 23 – 24 October 2017 in Boston. The title of her talk will be: “Extracellular vesicles microRNA (EV miRNA) as Bipolar Disorder (BD) Biomarkers”, based on her senior author paper published ahead of print on February
    • JessRitterDefense
    • Jessica (Allen) Ritter, PhD (Caroline Genco Lab) successfully defended her Thesis, “Induction of Human Macrophage Cell Death by Neisseria gonorrhoeae” on March 10th, 2017. BRAVO!!
    • Elizabeth Moses, PhD (Spira/Lenburg Lab) successfully defended her Thesis, “Characterizing the Airway Epithelium following Chemical Exposure: Molecular Alterations and their Potential Utility in the Treatment of Lung Disease” on March 21st, 2017. HOORAY!!
        • Liz andFriends
        •     LizPresentingandAviWatching
        •  Moses.DefenseTitle

     

     

    • News for Dr. Barbara Nikolajczyk:
      • Dr. Nikolajczyk gave a talk at the Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, Defining Inflammation in Human Obesity and Type 2 Diabetes, 2017
      • She also presented for The Hormel Institute, University of Minnesota, Austin, MN, Defining Inflammation in Human Obesity and Type 2 Diabetes, 2017
      • Dr. Nikolajczyk also received a Grant Title; “Does salt drive a human immune profile in a mouse model of obesity?” from the Boston University Nutrition and Obesity Research Consortium
    • Dr. David Sherr along with Dr. Stefano Monti and presenting work of Amy Li, gave an invited talk at the Clinical and Translational and Sciences Institute Symposium about development of a high throughput genomic platform to identifying which of the 84,000 chemicals in our environment are carcinogens.

    CTSI 2017 BU

    CTSI 2017 – BU

     

     

     

     

     

    • Nancy S. Miller, M.D. – was invited to teach a webinar for Rutgers, The State University of New Jersey, School of Health Professions , Department of Clinical Laboratory Sciences, on March 27 “Improved technology for microbial identification: challenges and lessons learned”
    • Welcome New Residents!:              
    •                                                                                                                                                                      Joanes
    • Marianinha Joanes
    • International American University
    • PGY-1
    • Yambayev
    • Iiyas Yambayev
    • Kazakh National Medical University
    •                                                  PGY-1

     

    • FASEB Capitol Hill Day 2017
          • On March 9, 2017 scientists from across the country gathered in Washington D.C. to participate in the Federation of American Societies for Experimental Biology (FASEB) Capitol Hill day. The purpose of the day was to advocate for federal funding for research, which includes the National Institutes of Health, National Science Foundation, Centers for Disease Control and other agencies.
          • The group met with congressional staff from the offices of our Representatives and Senators. During these meetings we emphasized the importance of research funding that drives scientific discoveries by sharing individual stories. We also emphasized how these scientific advances improve the care of patients and health of the nation. Information was provided about the positive economic impact of NIH and NSF funding for each state and congressional district.
          • Our specific request was to have research funded to the full amount in the 2017 budget. Since the federal government currently operates under a continuing resolution, NIH has been withholding 10% from grants until the budget has been finalized.
          • The Massachusetts representatives all strongly supported research funding. However, they were also pessimistic given the current political climate in Washington DC, even though there is strong bipartisan support for research.
          • This pessimism was justified when the White House released the first version of their budget, which calls for cutting the NIH budget by $5.8 billion, or 18%.
          • The Massachusetts delegation included Laura Coleman representing the American Society for Nutrition, Shoumita Dasgupta and Daniel Remick from Boston University School of Medicine and Boston Medical Center, Ming Ming Ning from Massachusetts General Hospital and Hanno Steen from Boston Children’s Hospital and Harvard Medical School. Derek Scholes the Director of Scientific Policy for the American Society of Human Genetics escorted us throughout the day.

        Kennedy picture

         

        • Publications ACCEPTED:
          • Leena P. Bharath, Blanche C. Ip, Barbara S. Nikolajczyk  Manuscript accepted into: “Adaptive immunity and metabolic health: harmony becomes dissonant in obesity and aging” Comprehensive Physiology
          • Woodworth, M., E.M. Neish, N. S. Miller, Tanvi Dhere, E.M. Burd, Cynthia Carpentieri, K. L. Sitchenko, and C.S. Kraft. Laboratory Testing of Donors and Stool for Fecal Microbiota Transplantation for Recurrent C. difficile Infection. Journal of Clinical Microbiology. Epub ahead of print 2017 Jan 11. doi:10.1128/JCM.02327-16. PMID: 28077694.
        • Publications PUBLISHED:
          • Chan GG, Koch CM, and Connors LH:  Blood proteomic profiling in inherited (ATTRm) and acquired (ATTRwt) forms of transthyretin-associated cardiac amyloidosis. J Proteome Res. 2017 Feb 14. doi: 10.1021/acs.jproteome.6b00998. [Epub ahead of print]  PMID: 28196416
          • Arvanitis M, Koch CM, Chan GG, Torres-Arancivia C, LaValley MP, Jacobson DR, Berk JL, Connors LH, Ruberg FL:  Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model.  JAMA Cardiol. 2017 Feb 8. doi: 10.1001/jamacardio.2016.5864. [Epub ahead of print]  PMID: 28196196
          • Wang Z, Monti S, DH S. The diverse and important contributions of the AHR to cancer and cancer immunity. Curr Opinion Toxicol. 2017 ;http://www.sciencedirect.com/science/article/pii/S2468202016300365
          • Blandine Bustamante Helfrich, MD, MPH, Nymisha Chilukuri, BSc, Huan He, PhD, MHS, MMgt, Sandra R. Cerda, MD, Xiumei Hong, MD, PhD, Guoying Wang, MD, PhD, Colleen Pearson, BA, Irina Burd, MD, Xiaobin Wang, MD, MPH, ScD. “DOI:Maternal vascular malperfusion of the placental bed associated with hypertensive disorders in the Boston Birth Cohort” http://dx.doi.org/10.1016/j.placenta.2017.02.016

         

         

         

        Departmental Seminar – March 24, 2017

        March 20th, 2017 in Spotlight

        Seminar Series: Fall 2016 ~~ Friday, February 17, 2017

        2:00-3:00 PM

                      

        “The Relationship of Retina to Brain Pathology in a Mouse Model of Concussive Traumatic Brain Injury

         

        Mark Wojnarowicz
        PhD Candidate, Goldstein Lab
        Department of Pathology and Laboratory Medicine
        Boston University School of Medicine

         

        Location & Time:
        670 Albany Street
        Lobby Level #107/108

        2:00-3:00 PM
        Friday, March 24, 2017

        Target Audience: Faculty, Students, Residents, Greater Boston Scientific Community (advertised in MIT’s Bulletin).

        Course Director: Barbara Slack, PhD

        Boston University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Boston University School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.

        Dissertation Defense – Tuesday, March 21, 2017

        March 14th, 2017 in Spotlight

        Dissertation Defense Seminar ~~ Tuesday, March 21, 2017

        2:00-3:00 PM

                      

        Characterizing the Airway Epithelium following Chemical Exposure:
        Molecular Alterations and their Potential Utility in the
        Treatment of Lung Disease

         

        Elizabeth Moses
        PhD Candidate
        Department of Pathology and Laboratory Medicine
        Boston University School of Medicine

         

        Location & Time:
        Instructional Building; L-112

        2:00-3:00 PM
        Tuesday, March 21, 2017

        Dissertation Defense – Friday, March 10, 2017

        March 8th, 2017 in Spotlight

        Dissertation Defense Seminar ~~ Friday, March 10, 2017

        10:00-11:00 AM

                      

        “Induction of Human Macrophage Cell Death by Neisseria gonorrhoeae

         

        Jessica (Allen) Ritter
        PhD Candidate
        Department of Pathology and Laboratory Medicine
        Boston University School of Medicine

         

        Location & Time:
        670 Albany Street
        Lobby Level #107/108

        10:00-11:00 AM
        Friday, March 10, 2017

         

        Departmental Seminar – February 24, 2017

        February 19th, 2017 in Spotlight

        Seminar Series: Fall 2016 ~~ Friday, February 24, 2017

        2:00-3:00 PM

                      

        Subha Singh, First Year MS Candidate
        (D. Anderson Lab)
        “Seminal Fluid and its Inflammation Properties on Vaginal Epithelium Cells”

        Department of Pathology and Laboratory Medicine
        Boston University School of Medicine

         

        Rawan Tahboub, First Year MS Candidate
        (Rahimi Lab)
        “Signal Transduction by Cell Adhesion Molecule, IGPR-1”

        Department of Pathology and Laboratory Medicine
        Boston University School of Medicine

         

        Location & Time:
        670 Albany Street
        Lobby Level #107/108

        2:00-3:00 PM
        Friday, February 24, 2017

        Target Audience: Faculty, Students, Residents, Greater Boston Scientific Community (advertised in MIT’s Bulletin).

        Course Director: Barbara Slack, PhD

        Boston University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Boston University School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.

        Departmental Seminar – February 17, 2017

        February 14th, 2017 in Spotlight

        Seminar Series: Fall 2016 ~~ Friday, February 17, 2017

        2:00-3:00 PM

                      

        “Process Improvements in Biobanking, in Partnership with the National Cancer Institute

         

        Chris Andry, MPHil, PhD
        Vice Chair for Operations and Management
        Associate Professor
        Director Masters Graduate Program
        Department of Pathology and Laboratory Medicine
        Boston University School of Medicine

         

        Location & Time:
        670 Albany Street
        Lobby Level #107/108

        2:00-3:00 PM
        Friday, February 17, 2017

        Target Audience: Faculty, Students, Residents, Greater Boston Scientific Community (advertised in MIT’s Bulletin).

        Course Director: Barbara Slack, PhD

        Boston University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Boston University School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.

        Pathology & Laboratory Medicine News Items – December 2016/January 2017

        February 1st, 2017 in Uncategorized

        Pathology & Laboratory Medicine News Items – December 2016/January 2017

        • Announcements:
            • The Pathology Residency and Cytopathology Fellowship Programs, are proud to announce the ACGME’s decision for the Continued Accreditation for both programs.  Congratulations and thanks to everyone for a job well done!
                  •  Rahimi.Cover.2016
              • Dr. Grace Zhao reported; “Congratulations, your Mallory Project is approved with a total budget of $6925. The approved budget is over the budget cap of $5000 because of the potential to expand the IHC list of stains within the Department”
              • Dr. Deborah Stearns-Kurosawa was invited to be a member of the scientific steering committee for the 10th International Symposium on Shiga Toxin (Verocytotoxin) Producing E.coli Infections (VTEC 2018) to be held in Florence, Italy in May 2018
              • Dr. Carmen Sarita-Reyes’s Mallory Proposal has been approved. The Department has provided funds for two medical students to participate in the 8 summer fellowship through the Mallory funds
              • Dr. Barbara Nikolajczyk presented at the following:
                • Endocrinology Grand Rounds, Boston University School of Medicine, Defining Inflammation in Human Obesity and Type 2 Diabetes, November 14 2016
                • Endocrinology Grand Rounds, University of Massachusetts School of Medicine, Defining Inflammation in Human Obesity and Type 2 Diabetes, December 13, 2016
              • Dr. Daniel  Remick presented in December:
                • Grand Rounds Speaker, Yale School of Medicine, Department of Pathology, “Traumatic Brain Injury Augments Host Defenses”
                • Grand Rounds Speaker, Boston Medical Center, Department of Internal Medicine, “Sepsis: A Moving Target”
              • Dr. Daniel Remick in January:
                • The Houston Methodist Hospital held their first Annual Pathology Research Day on Saturday, January 14th. First year pathology residents presented posters and the upper year residents and fellows each gave 5-7 minute presentation on their projects. Dr. Remick was the Keynote Speaker and gave the talk “Mild Traumatic Brain Injury Augments Innate Immunity”
              • Jason Sutin, PhD (Off-Site at MGH Franceschini Lab) successfully defended his Thesis, “Development of a Novel Diffuse Correlation Spectroscopy Platform for Neuromonitoring Cerebal Blood Flow and Oxygen Metabolism: From Novel Concepts and Devices to Preclinical Live Animal Studies” Fall 2016, BRAVO!!
              • Barbara Nikolajczyk, PhD received a $20,000.00 grant titled “Inflammation in type 1 diabetes” from Boston University CTSI
              • Dr. Nikolajczyk will also be a reviewer on two NIH panels in Feb:
                • Cellular Aspects of Diabetes and Obesity Study Section, Ad-hoc (2017)
                • NIDDK Fellowship and Conflict Study Section, Ad-hoc (2017)
                • New People:
                  • The Nikolajczyk Lab has added Joseph Lee, Masters in Nutrition student
            • Publications ACCEPTED:
              • Mahmoud L Soliman, MD PhD, Ashish Tiwari, MD, Grace Zhao MD, PhD “Coexisting tubular adenoma with a high-grade neuroendocrine carcinoma of colon allowing early surgical intervention and implicating a shared stem cell origin.” The World Journal of Gastroenterology
              • Li C, Wang D, Lv X, Jing R, Bi B, Chen X, Guo J, Wang F, Sun S, Azadzoi KM, Yang JH: Yersinia pestis acetyltransferase-mediated dual acetylation at the serine and lysine residues enhances the auto-ubiquitination of ubiquitin ligase MARCH8 in human cells. Cell Cycle (accepted for publication)
              • Nicholas DA, Proctor EA, Raval FM, Ip BC, Habib C, Ritou E, Grammatopoulos TN, Steenkamp D, Dooms H, Apovian CM, Lauffenburger DA and Nikolajczyk BS. 2017. Advances in the Quantification of Mitochondrial Function in Primary Human Immune Cells through Extracellular Flux Analysis (Accepted, PLOS ONE)
            • Publications PUBLISHED:
            • The Department’s strategic plan included increasing our academic stature. To achieve this the guidelines for Mallory Research Projects were sent to the faculty. There was an excellent response and the following Mallory proposals were funded in the Fall of 2016.
              1. Cell cycle regulator JADE1 protein: a novel marker of colon cancer in humans
                1. Drs. Panchenko, O’Brien and Tan
              2. Defining gene programs regulated by Ikaros in T cells
                1. Drs. Winandy and Lee
              3. Validation of Maspin/VHL immunostain for distinguishing carcinoma from reactive atypia in pancreas
                1. Drs. Tan, Yang, and Zha
              4. Local Release of Substance P after mild traumatic brain injury primes the host to survive a subsequent pathogen challenge
                • Drs. Remick and Kim

            Pathology & Laboratory Medicine News Items – November 2016

            December 5th, 2016 in Uncategorized

            Pathology & Laboratory Medicine News Items – November 2016

            • Announcements:
              • Dr. Shinichiro Kurosawa has been reappointed to the Boston University Laboratory Safety Committee. The term of his appointment is through December 31, 2018
              • Dr. Chris Andry has had his appointment extend as Chair of the Boston University Laboratory Safety Committee. The term of his extension is through December 31, 2018
              • Jacquelyn Sikora Hanson, PhD (Lawreen Connors Lab) successfully defended her Thesis, “Transthyretin gene regulation in wild-type transthyretin amyloidosis” on November 21st, 2016, BRAVO!!
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              • Dr. Sikora Hanson’s Defense Dissertation
              •                                                                                                                                                                                                                        Jacquelyn’s Thesis Committee: Dr. Vickery Trinkaus-Randall,
              • Dr. Lawreen Connors (PI), new Dr. Sikora Hanson and Dr. David Sherr              
              •      committee-trinkaus-randall-connors-hanson-sherr                                                                         

                                                                            

            • dr-hanson-and-family-stephen-brother-ginger-momandray-dad
            •                                                                     Dr. Jacquelyn Sikora Hanson and her proud family
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            • Shark Tank Winners. The Cancer Center held a retreat on November 29th that featured a “Shark Tank” styled competition for research funds. Prior to the retreat faculty were asked to submit brief proposals and the top 4 proposals were selected for presentation. During lunch each group had 5 minutes to make their pitch to the Sharks on the expert panel. David Sherr and Dan Remick submitted a proposal AHR Inhibitors as Novel Immune Checkpoint Inhibitors.  Their idea was selected as the winner. Portions of the funds will be used for processing specimens in the Ex+.

             

               

              Publications ACCEPTED:

              • Hot Off the Presses: The manuscript below has been accepted for publication in Neuropsychiatric Genetics.  While the first four authors worked in Dr. Ivana Delalle’s laboratory, it is really a multi-institutional effort that Dr. Delalle was fortunate to lead.  “Exosomal miR-149 and miR-29c as Candidates for Bipolar Disorder Biomarkers” by Jason L. Choi1, Patricia F. Kao1, Elena Itriago1, Yougen Zhan1, James A. Kozubek2, Andrew G. Hoss3, Meredith G. Banigan4, Charles R. Vanderburg4, Amir H. Rezvani5, Jeanne C. Latourelle3, Howard Cabral6, and Ivana Delalle1#; 1Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118; 2Broad Institute, Cambridge, MA 02142; Brigham and Women’s Hospital, Boston, MA 02112; 3Department of Neurology, Boston University School of Medicine, Boston, MA 02118; 4Advanced Tissue Resource Center, Harvard NeuroDiscovery Center, Charlestown, MA 02129; 5Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27710; 6Department of Biostatistics, Boston University School of Public Health and Boston University Clinical and Translational Science Institute, Boston, MA, 02118

              Publications PUBLISHED:

                The Department has been actively engaged in biobanking initiatives for several years. These important biobanking projects provide specimens to several investigators to help understand the basic mechanisms of disease. Banking these specimens also honors the patients’ wishes to provide tissue for research.On behalf of the patients who donated biospecimens, and investigators who use the biospecimens, thank you. Your efforts ensure that pathology provides high quality biospecimens.Here is the impressive list of current and recent projects, including the pathology personnel that are participating in each project.

                Biobanking grants in Pathology and Laboratory Medicine

                • 2016-2018: Thrombosis in Cancer Patients (TCP). Pre-analytic Variables that May Impact Standardization,
                • NCI. Contract award HHSN261200800001E  – $1.4M total cost
                • PI: Dr. Andry.
                • Co-I: Drs. Stearns-Kurosawa, Kurosawa, Henderson, Sloane, & Ms. Duffy, Sun
                • Other personnel: Cheryl Spencer, Morgan Thompson

                 

                •  2016-2017: Boston Medical Center Biospecimen Source Site for the Clinical Proteomic Tumor Analysis Consortium (CPTAC)
                • NCI contract HHSN261201600011I – $89,229.07.
                • PI: Dr. Andry
                • Co-I: Henderson
                • Other personnel: Spencer, Kim, Chen

                 

                • 2011-2017: Detection of Early Lung Cancer Among Military Personnel (DE-CAMP), pulmonary
                • Department of Defense W81XWH-11-2-0161 – $2,378,826
                • PI: Avrum Spira, M.D.
                •  Co-I: Remick, Pistey
                • Other personnel: Spencer

                 

                • 2016-present: Framingham Heart Study Biospecimen Core
                •  Lab Director – Dr. Henderson

                 

                • 2014-2016: Biospecimen Source Site for Cancer Human Biospecimens (caHUB).
                • NCI. Biospecimen Preanalytical Variables Program 11XS1007T1 – $332,508
                • Co-I: Drs. Pistey, Henderson
                • Other personnel: Spencer, Duffy

                 

                • 2014-2015: Biospecimen Source Site for the National Disease Research Interchange (NDRI)
                • Biospecimen procurement contract – $14,600
                • PI: Dr. Andry
                • Other personnel: Bondzie, Spencer

                 

                • 2013-2015: Tissue Source Site for The Cancer Genome Atlas Project (TCGA)
                • NCI. Initial Task Order 13XS114 – $15,350
                • PI: Dr. Andry
                • Co-I: Henderson
                • Other personnel: Spencer, Mei Cao

                Departmental Seminar – November 18, 2016

                November 14th, 2016 in Spotlight

                Seminar Series: Fall 2016 ~~ Friday, November 18, 2016

                2:00-3:00 PM

                              

                “Defining Humoral Correlates of Protection in Infection and Vaccination

                 

                Todd Suscovich, PhD
                Staff Scientist
                Ragon Institute of MGH, MIT, and Harvard

                 

                Location & Time:
                670 Albany Street
                Lobby Level #107/108

                2:00-3:00 PM
                Friday, November 18, 2016

                Target Audience: Faculty, Students, Residents, Greater Boston Scientific Community (advertised in MIT’s Bulletin).

                At the conclusion of this activity participants will be able to: 1)  recall that while antibody titers and neutralization are considered the gold standard for the selection of successful vaccines, these parameters are often inadequate predictors of protective immunity; 2) report that the authors used an integrative approach termed Systems Serology to analyze relationships among humoral responses elicited in four HIV vaccine trials and 3) state that although over 80 vaccines, covering more than 20 diseases, have been licensed in the United States, vaccine design efforts against persisting infections, including malaria, tuberculosis, and HIV, continue to fail.

                Course Director: Barbara Slack, PhD

                Boston University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Boston University School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.

                Departmental Seminar – November 4, 2016

                November 1st, 2016 in Spotlight

                Seminar Series: Fall 2016 ~~ Friday, November 4, 2016

                2:00-3:00 PM

                              

                “Effects of Tumor Evolution On Cancer Genomes

                 

                Rameen Beroukhim, MD, PhD
                Assistant Professor of Medical Oncology and Cancer Biology
                Dana-Farber Cancer Institute
                Assistant Professor of Medicine, Harvard Medical School

                 

                Location & Time:
                670 Albany Street
                Lobby Level #107/108

                2:00-3:00 PM
                Friday, November 4, 2016

                Target Audience: Faculty, Students, Residents, Greater Boston Scientific Community (advertised in MIT’s Bulletin).

                At the conclusion of this activity participants will be able to: 1) recall that recent studies have detailed the genomic landscape of primary endometrial cancers, but the evolution of these cancers into metastases has not been characterized; 2) state that endometrial cancer is the most common pelvic gynecological malig­nancy in industrialized countries, partially owing to the obesity epidemic and 3) report that across primary endometrial cancers, 21 new signifi­cantly mutated genes have been identified.

                Course Director: Barbara Slack, PhD

                Boston University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Boston University School of Medicine designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)™.  Physicians should only claim credit commensurate with the extent of their participation in the activity.