January 2012

February 1st, 2012

Pathology & Laboratory Medicine News Items

Announcements:

  • Boston Magazine has released its annual Top Docs issue and our own Dr. Antonio de las Morenas was once again on the list of “Top Docs” Congratulations Dr. de las Morenas
  • Dr. Ivana Delalle was an invited lecturer December 15, 2011 at the European Neuroscience Institute at Goettingen University, Germany. Her presentation was I entitled: “Identifying modulators of brain reserve and neuropathology in cognitive and mood disorders”
  • On January 3 Dr. Ivana Delalle became a Member of the Program Committee for the American Association of Neuropathologists Meeting in Chicago, June 2012
  • Dr. Michael Roehrl will be an invited speaker on “Integrating Proteomics and Genomics into Next Gen Systems Pathology” to be given at Cambridge Healthtech Institute’s Eighth Annual Biomarker World Congress in Philadelphia, PA (May 21-23, 2012)
  • Martin Steffen, PhD was interviewed about the role of phosphorylation in cancer and its treatment by OncLive.
  • Dr. Catherine Valentine has been awarded the ‘Mentored Clinical Scientist Development Award’ (KO8) entitled ‘Adenosine and TLR regulation of costimulatory molecule expression in sepsis’ awarded by the NIH for 5 years
  • ACCEPTED to USCAP 2012: USCAP 2012 conference is being  held at the Vancouver Convention Center, Vancouver, Canada from March 17-23: One of our residents, Manisha Mehta, MD has a poster to be presented on March 21st: “Identification of IGPR-1 as a Novel Cell Adhesion Molecule Involved in Tumor Growth and Angiogenesis” Manisha Mehta, Rosana D Meyer, John E. Mahoney,  Kobra  Rezazadeh, Nader Rahimi

 

Publications: PUBLISHED

  • Qin, X., Qu, X., Coy, D., and Weber, H. C.: A Novel Selective Human Bombesin Receptor Subtype-3 Agonist Mediates CREB Phosphorylation and Transactivation. Journal of Moecular lNeurosciences 2011; Nov 30. [Epub ahead of print]
  • Ishita Deb Majumdar, Arvind Devanabanda, Benjamin Fox, Jacob Schwartzman, Huan Cong, John A. Porco, Jr., and H. Christian Weber: Synthetic Cyclohexenyl Chalcone Natural Products Possess Cytotoxic Activities Against Human Prostate Cancer Cells and Inhibit Cysteine Cathepsins in vitro. BBRC 2011; 416: 397-402
  • Ishita Deb Majumdar and H. Christian Weber: Appetite-modifying effects of bombesin receptor subtype-3 agonists.  In: “The Handbook of Experimental Pharmacology” Volume 209; Appetite Control. Editor Hans-Georg Joost. Springer-Verlag Berlin Heidelberg 2012 (in press)
  • Ishita Deb Majumdar and H. Christian Weber: Biology and Pharmacology of Bombesin Receptor Subtype-3. Current Opinions in Endocrinology, Diabetes & Obesity 2012: 19(1):3-7
  • H. Christian Weber: Gastrointestinal Regulatory Peptides. Current Opinions in Endocrinology, Diabetes & Obesity 2012 :19(1):1-2
  • Hall NH, Conley K, Berry C, Farina L, Sigler L, Wellehan JF Jr, Roehrl MHA, Heard D.J Zoo “Computed tomography of granulomatous pneumonia with oxalosis in an American alligator (Alligator mississippiensis) associated with Metarhizium anisopliae var anisopliae.” Wildl Med. 2011 Dec;42(4):700-8
  • Jean-Bosco Tagne1, Sumeet Gupta2, Adam C. Gower3, Steven S. Shen4, Saaket Varma1, Meenakshi Lakshminarayanan1, Yuxia Cao1, Avrum Spira3,4, Thomas L. Volkert2, Maria I. Ramirez;  “Genome-Wide Analyses of Nkx2-1 Binding to Transcriptional Target Genes Uncover Novel Regulatory Patterns Conserved in Lung Development and Tumors” appeared in PLoS ONE on January 5th

 

Publications: Accepted

  • Johannes Gräff1,2,3, Ji-Song Guan1,2,3, Damien Rei1,2, Wen-Yuan Wang1,2,3, Krista M. Hennig3,4, Thomas J.F. Nieland3,4, Daniel M. Fass3,4, Patricia F.Kao5, Martin Kahn1, Nadine Joseph1,2,3, Stephen J. Haggarty3,4, Ivana Delalle5, and Li-Huei Tsai1,2,3,* “An epigenetic blockade of cognitive functions in the neurodegenerating brain” in Nature
  • Hernández-Pérez M, El-Hajahmad M, Massaro J, Mahalingam M. “Expression of gelatinases (MMP-2, MMP-9) and gelatinase activator (MMP-14) in actinic keratosis and in in situ and invasive squamous cell carcinoma.” (in press, American Journal of Dermatopathol, 2011)
  • Paniz-Mondolfi A, Talhari C, Sander Hoffmann L, Connor D, Talhari S, Bermudez A, Hernández-Pérez M, Van Bressem, MF. “Lobomycosis: An emerging disease in humans and delphinidae”  in press, Mycoses, 2011

December 2011

December 2nd, 2011

Pathology & Laboratory Medicine News Items

Announcements:

  • Boston Magazine has released its annual Top Docs issue and our own Dr. Antonio de las Morenas was once again on the list of “Top Docs” Congratulations Dr. de las Morenas
  • Dr. Michael Roehrl was an invited speaker on Ultra-Rapid Biobanking at the October 2011 Molecular Diagnostics for Personalized Medicine Conference in Hannover, Germany
  • Also Dr. Roehrl taught a new postgraduate course for pathologists on “Systems Pathology: An Introduction to Omic Approaches in Modern Personalize Medicine” for the American Society for Clinical Pathology (ASCP) at the Annual Meeting in Las Vegas in October 2011.
  • Dr. Roehrl will teach a related course at the next USCAP Meeting in Vancouver in March 2012
  • Dr. Michael Roehrl has just been re-elected as the IMG Delegate to the Massachusetts Medical Society (MMS) House of Delegates
  • Dr. Carl O’Hara gave the annual Stanley L. Robbins lecture to the New England Society of Pathologists on November 15th. This lecture is named in honor of Dr. Robbins, former Chair of Pathology and Laboratory Medicine at Boston University School of Medicine. Dr. O’Hara lecture “New Proposal for the Classification of Lung Adenocarcinoma: What Happened to BAC” was presented to a standing room only group of pathologists. After dinner Dr. O’Hara presented two cases of lung cancer to further illustrate how the changes in classification impact clinical care of the patients. There is tremendous symmetry with Dr. O’Hara giving the annual Robbins lecture, since he is also the recipient of the Stanley Robbins Teaching Award in 2011 from the Boston University School of Medicine.
  • Jacqueline Bouchard, PhD Candidate in the Remick Lab traveled to Loyola University Medical Center in Maywood, Illinois, for the Annual Alcohol and Immunology Research Interest Group (AIRIG) conference on November 18th, 2011.  Jackie gave both a poster and oral presentation of her work entitled “Ethanol Intoxication as a New Trigger for Atopic Asthma.”  Jackie also received a travel award funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to cover the entire cost of attendance.
  • Dr. Kendra Iskander, a surgical resident conducting research in the Remick Lab on a T32 Fellowship, was awarded a resident scholarship to attend the Society of Thoracic Surgeons meeting in Ft. Lauderdale this January.  It includes hotel, registration, and airfare.  The meeting should be good for networking and professional development.
  • Welcome to NEW FACES!
  • Nikolajczyk Lab: Dr. Jason DeFuria will be joining Barb Nikolajczyk’s lab Dec. 1 as a post-doctoral fellow and as a trainee of the Hematology Training Grant.  Jason got his PhD at Tufts and is an expert on obesity.
  • Panchenko Lab: Dr. Maria Panchenko has two new research technicians in the lab:
    • Joseph Haegele, recent graduate of Rensselaer Polytechnic Institute with degree in Chemistry
    • Sherry Blackmon, recent graduate of Bridgewater State University with degree in Molecular Biology
    • Both will be engaged in experimental research activities

 

Publications: PUBLISHED

  • Toribio Y, Roehrl MHA. The Nasolabial Cyst – A Non-Odontogenic Oral Cyst Related to Nasolacrimal Duct Epithelium. Archives of Pathology and Laboratory Medicine, November 2011

 

Publications: Accepted

  • Rahimi N. “Ubiquitin–Proteasome System Meets Angiogenesi” (Review). Molecular Cancer Therapeutics
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Pathology & Laboratory Medicine News Items – December 2011

n Announcements:

o Dr. Michael Roehrl was an invited speaker on Ultra-Rapid Biobanking at the October 2011 Molecular Diagnostics for Personalized Medicine Conference in Hannover, Germany

o Also Dr. Roehrl taught a new postgraduate course for pathologists on “Systems Pathology: An Introduction to Omic Approaches in Modern Personalize Medicine” for the American Society for Clinical Pathology (ASCP) at the Annual Meeting in Las Vegas in October 2011.

o Dr. Roehrl will teach a related course at the next USCAP Meeting in Vancouver in March 2012

o Dr. Michael Roehrl has just been re-elected as the IMG Delegate to the Massachusetts Medical Society (MMS) House of Delegates

o Dr. Carl O’Hara gave the annual Stanley L. Robbins lecture to the New England Society of Pathologists on November 15th. This lecture is named in honor of Dr. Robbins, former Chair of Pathology and Laboratory Medicine at Boston University School of Medicine. Dr. O’Hara lecture “New Proposal for the Classification of Lung Adenocarcinoma: What Happened to BAC” was presented to a standing room only group of pathologists. After dinner Dr. O’Hara presented two cases of lung cancer to further illustrate how the changes in classification impact clinical care of the patients. There is tremendous symmetry with Dr. O’Hara giving the annual Robbins lecture, since he is also the recipient of the Stanley Robbins Teaching Award in 2011 from the Boston University School of Medicine.

o Jacqueline Bouchard, PhD Candidate in the Remick Lab traveled to Loyola University Medical Center in Maywood, Illinois, for the Annual Alcohol and Immunology Research Interest Group (AIRIG) conference on November 18th, 2011.  Jackie gave both a poster and oral presentation of her work entitled “Ethanol Intoxication as a New Trigger for Atopic Asthma.”  Jackie also received a travel award funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to cover the entire cost of attendance.

o Dr. Kendra Iskander, a surgical resident conducting research in the Remick Lab on a T32 Fellowship, was awarded a resident scholarship to attend the Society of Thoracic Surgeons meeting in Ft. Lauderdale this January.  It includes hotel, registration, and airfare.  The meeting should be good for networking and professional development.

o Welcome to NEW FACES!

o Nikolajczyk Lab: Dr. Jason DeFuria will be joining Barb Nikolajczyk’s lab Dec. 1 as a post-doctoral fellow and as a trainee of the Hematology Training Grant.  Jason got his PhD at Tufts and is an expert on obesity.

o Panchenko Lab: Dr. Maria Panchenko has two new research technicians in the lab:

§ Joseph Haegele, recent graduate of Rensselaer Polytechnic Institute with degree in Chemistry

§ Sherry Blackmon, recent graduate of Bridgewater State University with degree in Molecular Biology

§ Both will be engaged in experimental research activities

n Publications: PUBLISHED

o Toribio Y, Roehrl MHA. The Nasolabial Cyst – A Non-Odontogenic Oral Cyst Related to Nasolacrimal Duct Epithelium. Archives of Pathology and Laboratory Medicine, November 2011

n Publications: Accepted

o Rahimi N. “Ubiquitin–Proteasome System Meets Angiogenesi” (Review). Molecular Cancer Therapeutics

November 2011

November 1st, 2011

Pathology & Laboratory Medicine News Items

Announcements:

  • Resident Marier Hernández-Pérez, MD had an abstract accepted for poster presentation at the Meeting of the 48th Annual Meeting of The American Society of Dermatopathologists (ASDP) in Seattle, WA in October. Marier Hernández-Pérez, MD; Mohamad El-hajahmad, MHCM; Meera Mahalingam, MD, PhD, FRCPath. “Expression of gelatinases (MMP-2, MMP-9) and gelatinase activator (MMP-14) in actinic keratosis and in in situ and invasive squamous cell carcinoma”
  • Our Cytopathology Fellowship has been approved by the ACGME until, September 2015
  • Madhu (Jangannathan) Bogdan PhD, successfully defended her thesis “CROSS-TALK BETWEEN ACTIVATED IMMUNE CELLS EXACERBATES INFLAMMATION IN TYPE 2 DIABETES” on October 28th
  • Dr. Carmen Sarita-Reyes presented a perinatology case at the Sociedad Latinoamericana de Patología Pediatrica (SLAPPE) on placental maturation defect on October 9th and 10th in Maceio, Brazil
  • Dr. Karen Quillen chaired a session at the AABB Annual Meeting in San Diego 10/23/11 entitled “Preventing hemolytic reactions from platelet transfusions: to screen or not to screen”
  • Resident Stephen Hammond, MD:
    • Won the Resident Leadership Award from the ASCP Annual Meeting 2011
    • Dr. Hammond presented his poster at the American Society of Clinical Pathology National Conference (ASCP) Meeting 2011: “Reducing Patient Waiting Times for Phlebotomy” Stephen Hammond, Janet Means, Jason Lumbrialdt, Martin Kroll.
    • Dr. Hammond also won Best Poster Award for poster referred to above at ASCP meeting 2011
Hammond - ASCP Leadership Award Stephen Hammond, MD (Leadership Award Recipient); Chris Coggbin, MD (Chair Resident Council ASCP); Bruce Alexander MD,(President ASCP) and Lili Lee, MD (Co- Leadership Award Recipient)
  • The Henderson Lab is going (en masse): Fangfang He, MD, Hui Chen, MD, Philip A Bondzie, Julie A. Tomolonis, Mostafa  Belghasem, MD Felita Agus, Joseph Coppola and Joel M. Henderson, MD, PhD; to the American Society of Nephrology Annual Meeting at “Kidney Week” in Philadelphia November 8-13 and some of the lab members will be presenting posters as mentioned in the October “New News”
  • Also from the Henderson Lab: Julie Tomolonis, a BU Senior in Cell and Molecular Biology, won a UROP FROG Award to support her Senior Honors Thesis work in the Renal Pathology Lab with Dr. Henerdon: “Cytotoxicity of amyloidogenic immunoglobulin light chains on human podocytes in culture”.  This project is a collaborative effort with Dr. Lawreen Connors and Dr. David Seldin at the Amyloid Center
  • Congratulations to Dr. Lija Joseph, her application to ICPI for matching funds for the Medical Student Interest Group Program has been approved
  • At the 2011 ASCP Annual Meeting/WASPaLM XXVI World Congress, October 19-22, Las Vegas, Dr. Martin Kroll gave a roundtable on “Interpreting Patient Results in the Presences of Biological Variation”, and a course on “Diagnostic Accuracy
  • Daniel G. Remick, MD was a visiting professor in the Department of Surgery at the University of Cincinnati and gave a talk “The Immunopathology of Traumatic Brain Injury”.  Dr. Remick was invited by the Vice Chair of Research, Alex Lentsch, Ph.D. to discuss and review their collaborative work to study the immunosuppressive effects of traumatic brain have already been initiated.
  • Daniel G. Remick, MD was a visiting professor in the Department of Microbiology and Immunology at Wayne State University and gave a presentation on “Alcohol and Asthma”. Dr. Remick was selected by the graduate students of Wayne State to be the visiting professor.
  • Nancy S. Miller, MD was co-convener for the symposium: “Evolving Technologies for Pathogen Detection” at the 46th Annual Region I Meeting of the American Society for Microbiology, October 26-27th 2011, Randolph, MA
  • Dr. Miller also presented a lecture, “Culture Shock! The Shift to New Technologies for In-Vitro Diagnostics in Clinical Microbiology” at the American Society for MicrobiologyIvana Delalle, MD, PhD just obtained a subaward in NIH RO1 “Epigenetics of Alzheimer’s Disease” grant initiated by Professor Tsai, Director of Picower Institute for Learning and Memory at MIT

Abstracts Accepted:

  • Patricia Kao, 4th year PhD candidate, has an abstract accepted for presentation at the 40th Annual Meeting of the International Neuropsychological Society in Montreal, Canada, February 15-18, 2012. Title: Exosomal miRNA profiling in prefrontal cortices of patients diagnosed with bipolar disorder and schizophrenia. Authors: Meredith Banigan, Patricia Kao, James Kozubek, Juan Medina, Joan Costa, Andrea Schmitt, Ivana Delalle, Charles Vanderburg

Publications: PUBLISHED

  • Maristela L Onozato1,2, Stephen Hammond3, Mark Merren2,  Yukako Yagi; Evaluation of a completely automated tissue-sectioning machine for paraffin blocks; Journal of Clinical  Pathology doi:10.1136/jclinpath-2011-200205
  • Azadzoi K, Yalla S, Siroky M: “Human bladder smooth muscle cell damage in disturbed oxygen tension” has been published in the November issue of the Urology Journal 78:967-72, 2011
  • Azadzoi K, Chen B, Radisavljevic Z, Siroky M: “Molecular reactions and ultrastructural damage in the chronically ischemic bladder” has been published in the November issue of the Journal of Urology 186(5):2115-22, 2011

Publications: Accepted

  • Jiyoun Kim, Sudha Natarajan, Louis J. Vaickus, Jacqueline C. Bouchard, Dominic Beal, William W. Cruikshank, and Daniel G Remick; Title “Diesel Exhaust Particulates Exacerbate Asthma-like Inflammation by Increasing CXC ChemokinesManuscript,” has been accepted for publication and currently available online version of the American Journal of Pathology In addition, this article was selected by the editor for further in-depth discussion about our findings in the article in the journal’s “Commentary” section.

October 2011

October 3rd, 2011

Pathology & Laboratory Medicine News Items

Announcements:

  • Poster Presentations at CAP (College of American Pathology Meeting), September 2011
    • “Intrauterine Death in the Second and Third Trimester of Pregnancy Associated With Umbilical Cord Hypercoiling and Hypocoiling” Opoku Adjapong, MD; Sandra Cerda, MD; Carmen Sarita-Reyes, MD
    • “Expression Profiles of Cytokeratin and Epithelial Membrane Antigen in the Sarcomatous Element of Müllerian Tumors” (Poster No. 10) Hao Wu, MD, PhD; Carmen Sarita-Reyes, MD; Sandra Cerda, MD
  • Dr. Carmen Sarita-Reyes will be presenting “Placental Listeriosis and Acute Chorioamnionitis” accepted for the 2011 Society of Pediatric Pathology Fall Meeting Perinatal Slide Seminar  to be presented in Milwaukee, WI on September 30th 2011
  • Tiffany Mellott, PhD has received a grant from the Simons Foundation Autism Research Initiative (SFARI) for her research entitled; “Perinatal choline supplementation: a therapeutic approach to autism.” To date, the Simons Foundation¹s single largest initiative has been in autism research. The SFARI program seeks to improve the diagnosis and treatment of autism spectrum disorders by funding, catalyzing, and driving innovative research of the greatest quality and relevance.
  • We thought everybody should know that the Kurosawa Lab is making a NEWS in The Journal of Nature Medicine
  • The Martin Steffen Lab research project aimed at uncovering gene function had a focus story written about it in Microbe Magazine
  • Dr. Remick’s Lab had a new NIH grant funded R01 GM 97320, Adenosine and Oxygen Modulate Antimicrobial Defenses. This grant grew out of work by one of the former pathology graduate students, Bryan Belikoff. The grant was funded for 4 years and the work will be done in collaboration with Dr. Sitkovsky at Northeastern University
  • Dr. Ivana Delalle has been invited to chair a session on Translational Neurology at an international conference in Beijing, China in May next year
  • Missy Cohen MT (ASCP) MPH, our Human Tissue Coordinator, has a poster accepted for AABB (American Association of Blood Banks) annual meeting October 22-25 in San Diego.  Poster title is; “ISBT 128 and the Future of Tissue Traceability.” Missy collaborated with SC Sharpe, Northside Hospital, Atlanta, GA and C Rushing, Tampa General Hospital, Tampa FL
  • Nancy S. Miller, MD has been appointed to the Membership Committee of the American Society for Microbiology (ASM), 2011-2014
  • Zach Hunter’s, PhD candidate, abstract has been selected by the American Society of Hematology (ASH) Program Committee for presentation in an Oral Session at the 2011 Annual Meeting of the ASH in San Diego, California in December 2011. Abstract Title: “Whole-Genome Sequencing Results From 30 Patients with Waldenstrom’s Macroglobulinemia”

 

Abstracts Accepted:

  • Abstract Accepted for American Society of Clinical Pathologists (ASCP) Meeting in Las Vegas, Nevada, October 2011:  “Reducing Patient Waiting Times for Phlebotomy.” Stephen Hammond MD, Janet Means, Neil O’Neill, Michael Khang, Jason Ladmirault, and Martin Kroll MD (Nominated as a Finalist for Best Poster submitted by a Resident Award and Best Poster in Lab Practice Management Award)
  • Dr. Joel Henderson and the Renal Pathology Lab have several abstract posters accepted for presentation at the 2011 American Society of Nephrology Annual Meeting (“Kidney Week”) in Philadelphia November 8-13:
    • Actinins Suppress Podocyte Contractility Fangfang He, MD*1, Hui Chen, MD1, Philip A Bondzie, PhD1, Julie A. Tomolonis1, Daniel J. Becker, MD, PhD2, Martin R. Pollak, MD3 and Joel M. Henderson, MD, PhD1. 1Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, United States; 2Division of Nephrology, Brigham and Women’s Hospital, Boston, MA, United States and 3Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, United States.
    • Effect of Amyloidogenic Immunoglobulin Light Chains on the Contractile Cytoskeleton of Human Podocytes In Vitro Laura Econimo, MD*1, Julie A. Tomolonis1, Laura M. Dember, MD, FASN2, David C. Seldin, MD, PhD2, Lawreen H. Connors, PhD2 and Joel M. Henderson, MD, PhD1.
    • 1Pathology and Laboratory Medicine, Boston University Medical Center, Boston, MA, United States and 2Amyloid Treatment & Research Center, Boston University Medical Center, Boston, MA, United States.
    • Myosin  Expression  and  Kidney  Structure  in  Older  Heterozygous Myh9  Knockout  Mice Mostafa  BelghasemMD*1,  Joseph  S  Coppola1, Philip  A  Bondzie, PhD1Hui  Chen,  MD1,  Julie  A.  Tomolonis1 and  Joel  M. Henderson,   MD,  PhD1. 1Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, United States
  • Abstract accepted in NeuroTalk-2012 “Exosomal and Cell-Population miRNA Profiling in Brain Tissue of Patients Diagnosed with Bipolar Disorder;” Patricia F. Kao, Kozubek J, Banigan M, Vanderburg C, and Delalle I*

 

Publications: PUBLISHED

  • Athanasios Zovoilis, Hope Y Agbemenyah, Roberto C Agis-Balboa, Roman M Stilling, Dieter Edbauer,  Pooja Rao, Laurent Farinelli, Ivana Delalle, Andrea Schmitt,  Peter Falkai,  Sanaz Bahari-Javan, Susanne Burkhardt,  Farahnaz Sananbenesi &  Andre Fischer: “microRNA-34c is a novel target to treat dementias” The EMBO Journal doi:10.1038/emboj.2011.327
  • Gillespie, E., Leeman SE., Watts LA., Coukos J., O’Brien MJ., Cerda, JR., Farraye, FA., Stucchi, AF., Becker, JM. “The Truncated Neurokinin-1 receptor is Increased in Colonic Epithelial Cells from Patients with Colitis-Associated Cancer.”  Proceedings of the National Academy of Sciences (USA).  In Press, Published online as of October 3rd, 2011
  • Moitra R, Beal DR, Belikoff BG, Remick DG. “Presence of Pre-Existing Antibodies Mediate Survival in Sepsis.” Shock, September 2011, in press (PMID:21921828)

 

Publications: ACCEPTED

  • Tan, Josenia, Burke, Peter, Agarwal, Suresh, Mantilla-Rey, Nelson & Quillen, Karen: “A MASSIVE TRANSFUSION PROTOCOL INCORPORATING A HIGHER FFP: RBC RATIO IS ASSOCIATED WITH DECREASED USE OF RECOMBINANT ACTIVATED FACTOR VII IN TRAUMA PATIENTS” has been accepted for publication in the American Journal of Clinical Pathology

September 2011

September 15th, 2011

Pathology & Laboratory Medicine News Items

 

Announcements:

  • Dr. Nader Rahimi has been awarded an Ignition Award from the Office of Technology of Boston University for development of humanized blocking monoclonal anti-IGPR-1 antibody for the treatment of human Lung Cancers. The provisional patent also has been filed for this novel technology.
  • Please give a warm welcome to our new students
    • Jessica Allen; PhD Candidate
    • Lujain Al-Sowaimel, MA Candidate
    • Laura Anthony, MA Candidate
    • Mostafa Belghasem, PhD Candidate
    • Chad Mayer, MD/PhD Candidate
    • Caitlin Miller; PhD Candidate
    • Timothy Norman, MA Candidate
    • John Veltre, MA Candidate
  • The summer has a flurry of activities going on with students interning from high schools and colleges in several pathology labs!
    • The Office of Summer Term’s program, Research Internship in Science and Engineering (RISE), once again offered rising high school seniors the opportunity to participate in basic science research for six weeks.  Forty-three students are places throughout the BU community and several were place in the Pathology and Immunology Departments:
      • Tim Elton in the Remick Lab hails from Detroit Country Day School, High School in Detroit, Michigan
      • Dave Sperber in the Remick Lab arrives from Bergin County Academies High School, Hackensack, New Jersey
      • Christopher Ng in the Kurosawa Lab comes from Monta Vista High in Cupertino, CA
      • Sharath Reddy was in the Cruikshank Lab, she is from Sacramento High School in California
    • These experiences culminated in a Poster Presentation on the Charles River Campus
PHOTO 1. RemickLabw-SummerStudents2011.Poster 08122011-14 Mentors Jackie Bouchard and Ritu Moitra, PhD Candidates with RISE Students, Dave Sperber and Tim Elton
PHOTO 2.Kurosawaw-SummerStudent2011.Poster 08122011-17 RISE Student Christopher Ng, Kurosawa Lab Members:  Caitlin Leibowitz, PhD Candidate and Danielle Day, Lab Technician

PHOTO 3.Dave Sperber PresentionPoster 08122011-5 Dave Sperber, RISE Student explaining his poster research

 

  • John Kim, PhD in the Remick Lab had junior Fay Feghali from Phillips Academy, who did a project entitled: “Optimization of bronchoalveolar lavage to minimize the variation of total cell numbers in a mouse model of asthma”
  • Dr. William Cruikshank also had Patrick Memari from Washington and Jefferson College, Washington, Pennsylvania. Patrick was here on a Howard Hughes Medical Institute Award granted through his college. Patrick’s project was entitled; “”Loss of Pro-IL-16 induces apoptotic resistance in T cells”
  • At the recent American Association for Clinical Chemistry (AACC) Annual Meeting , in Atlanta, Georgia (July 23-28th), Dr. Martin Kroll gave several presentations, including:
    • What Does It Take to Achieve Good Precision?  Enhancing Laboratory Operations Through Analytical Quality and Informatics
    • Biological Variation:  The Often Forgotten Source of Variation in Laboratory Test Results
    • Advantages and Challenges of the HIV Ag/Ab Combo Test
    • Dr. Kroll also presented at a roundtable on Laboratory Management
  • On behalf of Dr. Debbie Stearns-Kurosawa:  Please welcome Josh Brand to our Pathology Department.  Josh is a graduate of Tufts University (undergrad and Master’s program) and will be working as a full-time technician in the Kurosawa lab.  He’s a native of Miami, FL , teaches break dancing and has the good sense to be a fan of the Pittsburgh Steelers
  • Dr. Maria Panchenko, PhD was awarded a 5-year NIH grant; RO1 DK087910-01A1: “Histone Acetyl Transferase HBO1 in kidney epithelial cell cycle”

 

Abstracts Accepted:

  • Abstract accepted for publication in The EMBO Journal; MICRO-RNA-34C IS A NOVEL TARGET TO TREAT DEMENTIAS by Zovoilis , Agbemenyah, Agis-Balboa , Stilling , Rao , Edbauer , Farinelli , Delalle , Schmitt, Falkai , Bahari-Javan, Burkhardt , Sananbenesi and Fischer
  • Abstract accepted for poster presentation at the 48th Annual Meeting of the American Society of Dermatopathologists in Seattle, Washington; October 2011. “Expression of gelatinases (MMP-2, MMP-9) and gelatinase activator (MMP-14) in actinic keratosis and in in situ and invasive squamous cell carcinoma”  Marier Hernández-Pérez, MD; Mohamad El-hajahmad, MHCM; Meera Mahalingam, MD, PhD, FRCPath.
  • Abstract accepted to American Journal of Pathology “Diesel Exhaust Particulates Exacerbate Asthma-like Inflammation by Increasing CXC Chemokines” Jiyoun Kim, Sudha Natarajan, Louis J. Vaickus,  Jacqueline C. Bouchard, Dominic Beal, William W. Cruikshank, and Daniel G Remick

 

Publications: PUBLISHED

  • Resident Stephen Hammond, MD had a recent paper published: Daichi Hayashi, Stephen Hammond, Ali Guermazi; “Gastroenteropancreatic neuroendocrine tumors: multimodality imaging features with pathological correlation;” Japanese Journal of Radiology Mar 2011;29: 85-91
  • Recent publication from Kurosawa Lab:  Stearns-Kurosawa DJ, Collins V, Freeman S, Debord  D, Nishikawa K, Oh S-Y, Leibowitz CS, Kurosawa S.   Rescue From Lethal Shiga Toxin 2-induced Renal Failure with a Cell-Permeable Peptide.  Pediatric Nephrology, 2011, in press (PMID: 2160390)
  • Dr. Sandra Cerda has a paper published: Soucy G, Wang HH, Farraye FA, Schmidt JF, Farris AB, Lauwers GY, Cerda SR, Dendrinos KG, Odze RD. “Clinical and pathological analysis of colonic Crohn’s disease, including a subgroup with ulcerative colitis-like features,” Modern Pathology 2011 Aug 12. doi: 10.1038/modpathol.2011.120. [Epub ahead of print] Mod Pathol.

 

Publications ACCEPTED:

  • Sudha Natarajan, Jiyoun Kim, Jacqueline Bouchard, William Cruikshank, Daniel Remick. “Pulmonary Endotoxin Tolerance Protects against Cockroach Allergen-induced Asthma-like Inflammation in a Mouse Model.” Accepted for publication in International Archives of Allergy and Immunology
  • Michael H. A. Roehrl, Marier Hernandez, Shi Yang, Thomas G. Christensen, Claudio Morera, and Julia Y. Wang “Helicobacter Heilmannii Gastritis in a Young Patient with Pets” Gastrointestinal Endoscopy (2011, in press)
  • Azadzoi K, Chen B, Radisavljevic Z, and Siroky Mike: “Molecular Reactions and Ultrastructural Damage in the Chronically Ischemic Bladder” has been accepted for publication in the American Journal of Urology

August 2011

August 1st, 2011

Pathology & Laboratory Medicine News Items

Announcements:

  • Supraja Narasimhan PhD, successfully defended her thesis “The Role of the Constitutively Active Aryl Hydrocarbon Receptor in Mammary Tumor Progression” on July 11th
  • Dr. Susan Winandy has received an R03 grant from the NIH entitled “Generation of Ikaros conditional knockout mice”!
  • Parul Agnihotri, rising 2nd year PhD Candidate in the Winandy Lab has been awarded a position on the ITP training grant
  • Shinichiro Kurosawa, MD, PhD was invited to the International Society of Thrombosis and Haemostasis meeting in Kyoto, Japan to give a talk describing the role of sepsis in the lethal complications of B.anthracis infections, and an oral abstract presentation describing the lab’s recent observations with treating infections from Shiga toxin-producing E.coli
  • Dr. Barbara Nikolajczyk was involved in field work for the “One Health” Project in Ecuador the first two weeks in July, in collaboration with the Ecuadorian FUCOBI Foundation.  This work involved collecting samples from coastal residents to query relationships between blood levels of environmental pollutants and the astonishing rate of type 2 diabetes in the poor of Ecuador. The project included presentation of Dr. Nikolajczyk’s BUSM type 2 diabetes work at three Ecuadorian Universities: Universidad de San Francisco de Quito, Universidad Tecnica de Machala (Machala), and Escuela Superior Politecnica del Litoral (Guayaquil). Establishment of a Memorandum of understanding between BU and the FUCOBI Foundation in 2011 will provide BU students opportunities for joining the project for field work experience as soon as summer 2012.
  • Dr. Daniel Remick chaired the advocacy presentations at the Association of Pathology Chairs annual meeting. The invited speaker was Dora Hughes, M.D., Counselor to Health and Human Services Secretary Kathleen Sebelius. Dr. Hughes spent two hours at the meeting, presenting the federal government’s perspective on health care reform and how it would impact the field of pathology.

Publications: PUBLISHED

  • Resident Stephen Hammond, MD had a recent paper published: Daichi Hayashi, Stephen Hammond, Ali Guermazi; “Gastroenteropancreatic neuroendocrine tumors: multimodality imaging features with pathological correlation;” Japanese Journal of Radiology Mar 2011;29: 85-91
  • Recent publication from Kurosawa Lab:  Stearns-Kurosawa DJ, Collins V, Freeman S, Debord  D, Nishikawa K, Oh S-Y, Leibowitz CS, Kurosawa S. Rescue From Lethal Shiga Toxin 2-induced Renal Failure with a Cell-Permeable Peptide.  Pediatric Nephrology, 2011, in press (PMID: 2160390).

Publications ACCEPTED:

  • Sudha Natarajan, Jiyoun Kim, Jacqueline Bouchard, William Cruikshank, Daniel Remick. “Pulmonary Endotoxin Tolerance Protects against Cockroach Allergen-induced Asthma-like Inflammation in a Mouse Model.” Accepted for publication in International Archives of Allergy and Immunology
  • Maristela L Onozato, Stephen Hammond, Mark Merren, Yukako Yagi  Paper: “Evaluation of a completely automated tissue-sectioning machine for paraffin blocks.” Accepted for publication in Journal of Clinical Pathology August 2011 (collaboration of Dr. Stephen Hammond and the MGH digital pathology group)

July 2011

July 8th, 2011

Pathology & Laboratory Medicine News Items

Announcements:

  • Laboratory Medicine’s New Facilities at 670 Albany Street had a very successful Open House Ribbon-Cutting Ceremony on Tuesday, June 21st. The event was attended by more than 70 people including Kate Walsh, Boston Medical Center’s President and CEO; Boston University Medical Center’s Dean Karen Antman as well as many distinguished guests and BMC/BUSM colleagues. Attendees were treated to informative, interesting tours of the facility and refreshments to celebrate the seamless transition.  Congratulations for a job well done!
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    Click Here for more photos from Open House

    • Zach Hunter, PhD candidate was an invited speaker for the Complete Genomics Users Group Meeting in San Francisco (Paired Tumor Normal WGS Studies in Waldenstrom’s Macroglobbulinemia) in June 2011
    • Congratulations on passing the Qualifying Exams!
      • Philip Bondzie
      • Evan Chiswick
      • Clarissa Koch
      • Jed Mahoney
      • David Stepien
    • Thank you to all faculty members who assisted with the qualifying exams, with a SPECIAL Thank You Dr. Bohdana Burke
    • BU Pathology is receiving national press for Dr. John (Jiyoun) Kim’s piece: “Herbal Medicine Treatment Reduces Inflammation in a Murine Model of Cockroach Allergen-Induced Asthma;” Jiyoun Kim1PhD, Sudha Natarajan1 PhD, Hyunsu Bae2 MD, PhD, Sung-Ki Jung2 MD, PhD, William Cruikshank3 PhD and Daniel G Remick1 MD published in the Annals of Allergy, Asthma & Immunology. Please take a look at the BUMC front pageScience Daily; and The European Lung Foundation;
    • Michael Roehrl, M.D., Ph.D., was invited to give a lecture on Systems Pathology at the Cancer Center of the Friedrich Schiller University in Jena, Germany, in June 2011
    • Dr. Roehrl is also an invited speaker at the Molecular Diagnostics for Personalized Medicine Conference in Hannover, Germany, in October 2011
    • Barbara Nikolajczyk, PhD will be traveling to Ecuador the first 1/2 of July for field work on the One Health Project run by the FUCOBI Foundation, based in Ecuador.  The goal of the project is to assess relationships between industrialization, industrial pollution, and the astonishing rates of obesity and type 2 diabetes among the local Ameridians (native population).  The project is in year 2 of a ten year pan, and anyone interested in joining the group next year is encouraged to get in touch with Dr. Nikolajczyk directly; bnikol@bu.edu
    • Dr. Karen Quillen has been appointed to the Department of Health and Human Services Advisory Committee for Blood Safety and Availability for a 4-year term beginning June 7, 2011. This Committee reports to the Secretary of HHS on major issues regarding the safety and availability of blood in the country, and also on organ transplantation.
    • Heather Cohen, 5th year PhD candidate was informed that her abstract has been accepted for poster presentation during the 12th International Workshop on Scleroderma Research 2011 at Trinity College Cambridge, United Kingdom July 24-27, 2011. Heather’s poster is titled: “Fli1 is Involved in Bleomycin-induced Lung Fibrosis and Inflammation”
    • Dr. Martin Kroll has been appointed as a member to the FDA’s Clinical Chemistry and Clinical Toxicology Devices Panel
    • Dr. Kroll also recently completed a CAP SAM, self-assessment module.  Every year newly board-certified Pathologists must earn at least 10 of these credits. Continuing education credits are required for maintaining board certification

    Publications ACCEPTED:

    • Azadzoi K, Yalla S, and Siroky M: “Human Bladder Smooth Muscle Cell Damage in Disturbed Oxygen Tension” has been accepted for publication in the Urology Journal
    • Dr. Michael Roehrl and others from the Pathology Department had the following accepted for publication: Roehrl MHA*, Alexander MP, Hammond SB, Ruzinova M, Wang JY, O’Hara CJ. Eosinophilic myocarditis in hypereosinophilic syndrome. American Journal of Hematology 2011; 86: 607-608. *Corresponding author
    • Paper accepted (Dr. Michael Roehrl showed by X-ray diffractometry that the pulmonary crystals were indeed calcium oxalate monohydrate/whewellite): Hall NH, Conley K, Berry C, Farina L, Sigler L, Wellehan JFX, Roehrl MHA, Heard D. Computed tomography of granulomatous pneumonia with oxalosis in an American alligator (Alligator mississippiensis) associated with Metarhizium anisopliae var. anisopliae. Journal of Zoo and Wildlife Medicine 2011 (in press).

    June 2011

    June 3rd, 2011

    Pathology & Laboratory Medicine News Items

    Announcements:Grad-297

    • Dr. Carl O’Hara is this year’s recipient of the prestigious Stanley L. Robbins Award for 2011.
      • The Stanley L. Robbins Award for Excellence in Teaching is given each year at graduation to the outstanding educator at the School of Medicine.  The award was established in recognition of the excellence in teaching and devotion to students exemplified by Dr. Stanley L. Robbins, former Chair and Professor of Pathology at BUSM. This award serves to acknowledge the importance of teaching skills and commitment to students and education at BUSM. This is a once in a lifetime award!
    • Michael H. A. Roehrl, M.D., Ph.D., has been invited by the German Scholars Organization (GSO) to a conference in Berlin, Germany, in June 2011. A small group of scientists from around the world with close ties to Germany will meet leaders from German politics (including the President and Cabinet Ministers), business, and academia to discuss strategies and policies to promote and grow top-level research and innovation in Germany and Europe
    • Congratulations to this year’s Russek Award recipients in the Department of Pathology:
      • First Prize- Jillian Richmond, Cruikshank Lab
      • Second Prize- Srimathi Srinivasan, Rahimi Lab
      • Honorable Mention- Rituparna Moitra, Remick Lab
      • Dr. Barbara Slacks says: Congratulations to the award winners, and thanks to everyone who submitted abstracts for the poster session.
    • June is PhD Qualifying Exams Month! This year May 31st will be the written part of the exam, June 8th and 9th the oral portion will take place. There are 5 students who will be taking their qualifying exams this season: Philip Bondzie, Evan Chiswick, Clarissa Koch, Jed Mahoney and David Stepien. The faculty working with this group of candidates is: Drs. Krzysztof Blusztajn, Bohdana Burke, Ivana Delalle, Nader Rahimi, Daniel Remick, Jackie Sharon, Barbara Slack, Jay Mizgerd and Susan Winandy. Good Luck to all! Thank you to Dr. Bohdana Burke again for her continuing excellent efforts coordinating the Qualifying Exams!
    • The American Board of Pathology has invited Dr. Martin Kroll to serve as a member designate on the Test Development and Advisory Committee on Chemical Pathology for 2012
    • Caitlin Leibowitz, 1st year graduate student in the Kurosawa Lab was awarded a research grant from the Boston University Mallory Research Fund for her project entitled: Establishment of mouse models for Escherichia coli infection and Shiga toxin type-2 challenge for studies that address systemic Shiga toxin distribution and organ damage in vivo.   Caitlin is finishing her first year of graduate studies in the Pathology Department and this award reflects her outstanding talent and passion for scientific research.
    • Srimathi Srinivasan, 3rd year PhD candidate in the Rahimi Lab has her abstract accepted for poster presentation in Gordon Research Conference. The title of her poster is “The PDCL3/CCT chaperonin complex regulates angiogenesis through the generation of functional VEGFR-2″ held June 19-24 2011 in New Hampshire
    • Srimathi Srinivasan, 3rd year PhD candidate in the Rahimi Lab has also been awarded a travel award by Boston University GMS office for her work to be presented at Gordon Research Conference, June 19-24 2011 in New Hampshire
    • Carmen Sarita-Reyes, MD has let me know that the abstract titled “Intrauterine Death in the Second and Third Trimester of Pregnancy Associated to Umbilical Cord Hypercoiling and Hypocoiling” was accepted for CAP 2011. Authors: Opoku Adjapong, Sandra Cerda and Carmen D. Sarita-Reyes

    Publications ACCEPTED:

    • Michael Roehrl, MD has a paper accepted: Roehrl MHA* and Farraye FA. Capillary “Esophageal hemangioma in a patient with systemic sclerosis and gastric antracl vascular extasia”. Gastrointestinal Endoscopy 2011 (in press). *Corresponding author. (Journal IF: 6.713)
    • Resident, Dr. Miriam Alexander has a paper accepted for publication in the American Journal of Kidney Disease: “Crescentic Renal Alpha Heavy Chain Deposition Disease: A Report of Three Cases with Review of Literature” M. Alexander, S. Nassr and H. Rennke
    • Dr. Lija Joseph has a piece accepted for publication in Circulation: Shenouda SM, Widlansky ME, Chen K, Xu G, Holbrook M, Tabit CE, Hamburg NM, Frame AA, Caiano TL, Kluge MA, Duess M-A, Levit A, Kim B, Hartman M-L, Joseph L, Shirihai OS, Vita JA. “Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus.” Circulation (in press).

    May 2011

    May 5th, 2011

    Pathology & Laboratory Medicine News Items

    Announcements:

    • 34th Annual SHOCK Society Meeting 2011, June 11-14; Norfolk, Virginia
      • David Stepien, 2nd year MD/PhD candidate in the Remick Lab will be presenting a poster Traumatic Brain Injury Impairs the Immune Response to Early Onset Pneumonia
      • Kendra Iskander, Surgical Resident and Remick Lab member will be presenting orally at this year’s 34th Annual SHOCK Meeting.  The title of her talk is “SHORTER DURATION OF POST-OPERATIVE ANTIBIOTICS IN PERITONITIS-INDUCED SEPSIS DOES NOT INCREASE INFLAMMATION OR MORTALITY”
      • Catherine Valentine, MD will be giving an oral presentation at the shock meeting entitled ‘Costimulatory Expression Profiling in Septic Shock’
      • Rituparna Moitra, 3rd year PhD candidate in the Remick Lab will give an Oral Presentation at SHOCK titled “PRE-EXISTING ANTIBODIES MEDIATE SEPSIS SURVIVAL”
      • Rituparna Moitra, 3rd year PhD candidate in the Remick Lab received the following:
        • Dr Moitra, It gives me great pleasure to inform you that you have been selected as a finalist for the New Investigator Award at the annual meeting of the Shock Society for your work titled ‘PRE-EXISTING ANTIBODIES MEDIATE SEPSIS SURVIVAL’.  This comes with a $350 prize collected at the meeting.  You will be presenting your paper in a session with 4 others, and the Awards Committee will select the best among these for the award.  The Award will consist of listing the name of the winner with past luminaries in the Archives of the Society as well as a $600 check and winner’s plaque in lieu of the $350 finalist prize….
    • The Kurosawa Lab has two abstracts accepted for the annual Shock Society meeting:
      • DJ Stearns-Kurosawa, Valta Collins, Scott Freeman, Diann Henthorn, Shinichiro Kurosawa.  “Rescue of nonhuman primates from lethal Shiga toxin-2 with a cell permeable peptide.”  34th Annual Conference on Shock, The Shock Society, Norfolk, Virginia, June 11 – 14, 2011.
      • Sun-Young Oh, Danielle Day, DJ Stearns-Kurosawa, Shinichiro Kurosawa.  “Shiga toxins trigger endoplasmic reticulum stress responses in human endothelial cells.”  34th Annual Conference on Shock, The Shock Society, Norfolk, Virginia, June 11 – 14, 2011
    • Laboratory Medicine moved into it’s new facilities at 670 Albany Street – 7th floor on May 1st!
    • Michael Roehrl, M.D., Ph.D., has been invited as a speaker at Institute for International Research’s 4th Annual Biorepositories Conference from September 19-21 in Boston, MA
    • Jillian Richmond, PhD, successfully defended her thesis “Subversion of Host Immunity by Mycobacterium Tuberculosis: Inhibition of PI3K/AKT by Mannose Lipoarabinomannan Hinders Th1 cell Migration and Promotes Soluble TNF Receptor Production” on April 1st
    • Patrick Tylek completed his Master’s thesis project in the Kurosawa Lab studying “”EGF Effects on Intestinal Epithelial Cells Against Shiga Toxin”
    • Martin Kroll, MD gave a presentation entitled “Immunoassays on Architect Systems” at the Northeast Regional Medical Laboratory Conference in Boxborough, MA. on April 12, 2011
    • Martin Kroll, MD also presented the poster: “The Spontaneous Vertical Movements Seen During Fixation Are Chaotic” MI Rosenberg, V Punia, R Bitra, M Kroll.  2538-A65at the Association for Research in Vision and Ophthalmology (ARVO) 2010 Annual Meeting. May 2-6, 2010,  Greater Fort Lauderdale/Broward County Convention Center, Florida
    • Nancy S. Miller, MD has been elected to serve as a Local Councilor for the Northeast Branch of the American Society for Microbiology (NEB-ASM), for a 3-year term to start July 1, 2011

    Publications ACCEPTED:

    • Martin Steffen, MD had a paper accepted in Molecular Medicine; “Pre-stroke proteomic changes in cerebral microvessels in stroke-prone, transgenic[hCETP]-hyperlipidemic, Dahl salt-sensitive hypertensive rats”Agnes Bergerat, PhD, Julius Decano, MD,, Chang-Jiun Wu, PhD, Hyungwon Choi, PhD, Alexey Nesvizhskii, PhD, Ann Marie Moran, MS,, Nelson Ruiz-Opazo, PhD,, Martin Steffen, MD PhD*, Victoria L.M. Herrera, MD*
    • Chief Resident, Dr. Marier Hernandez-Perez has a paper accepted for publication in the American Journal of Dermatopathology: Hernández-Pérez M and Mahalingam M. “MATRIX METALLOPROTEINASES IN HEALTH AND DISEASE: Insights from Dermatopathology”
    • The Kurosawa Lab has the following accepted for publication: Stearns-Kurosawa DJ, Collins V, Freeman S, Debord  D, Nishikawa K, Oh S-Y, Leibowitz CS, Kurosawa S. “Rescue From Lethal Shiga Toxin 2-induced Renal Failure With A Cell-Permeable Peptide,”  Pediatric Nephrology, 2011, in press
    • The Remick Lab has an article accepted for publication: “Herbal Medicine Treatment Reduces Inflammation in a Murine Model of Cockroach Allergen-Induced Asthma;” Jiyoun Kim1PhD, Sudha Natarajan1 PhD, Hyunsu Bae2 MD, PhD, Sung-Ki Jung2 MD, PhD, William Cruikshank3 PhD and Daniel G Remick1 MD in the Annals of Allergy, Asthma & Immunology

    Publications-PUBLISHED:

    • Dr. Marier Hernandez-Perez current Chief Resident has a paper coming out in the May edition of the International Journal of Dermatology: Paniz-Mondolfi AE, Pérez-Alvarez AM, Lundberg U, Fornés L, Reyes-Jaimes O, Hernández-Pérez M, Hossler E. “Cutaneous lepidopterism: dermatitis from contact with moths of Hylesia metabus (Cramer 1775) (Lepidoptera: Saturniidae), the causative agent of caripito itch”. International Journal of Dermatology 2011 May;50(5):535-541
    • Dr. Mary Jo Murnane has a paper is coming out in Human Pathology this month: Mary Jo Murnane, Ph.D.; Jinquo Cai, M.S.; Sania Shuja, M.D., Ph.D.; David McAneny, M.D.; John B Willett, Ph.D.     Active MMP-2 Activity Discriminates Colonic Mucosa, Adenomas with and without High Grade Dysplasia and Cancers.  Human Pathology 42:688-701, May 2011

    April 2011

    April 4th, 2011

    Pathology & Laboratory Medicine News Items

    Announcements:

    • Experimental Biology Conference 2011: April 9-13; Washington DC
      • Jackie Bouchard, 4th year PhD candidate will be presenting a poster at this year’s Experimental Biology Conference.  The title is “Binge drinking rapidly triggers asthma-like pulmonary inflammation in cockroach-allergen sensitized mice.”  It will be presented in the poster session entitled “Inflammation and Immunopathology” Sunday, April 10, 2011
      • Dominic Beal, 3rd year PhD Candidate will be presenting orally at this year’s Experimental Biology Conference.  The title of his talk is “Acute alcohol exposure alters the lymphocyte profile in cockroach-allergen (CRA) induced allergic mice.”  It will be presented in the oral session entitled “Inflammation and Immunopathology” on Saturday, April 9, 2011
    • Joel Henderson, MD was invited to attend the Boston University Medical Campus Emerging Leaders Forum, March 23 and 24 at the Wellesley College Club
    • The Department of Pathology and Laboratory Medicine recently invited medical students to participate in a creative educational project incorporating basic science content into the clinical years. Over 30 students applied for the project award and the students listed below were selected to participate. Three are MD/PHD students with specific interest in medical education; each student is awarded 500 dollars from a recent grant obtained by the department from the American Society of Investigative Pathology. Dr. Carl O’Hara, Dr. Lija Joseph from our department and Dr. Kitt Shaffer from the Radiology Department will be mentoring the students. If any faculty has an interest in participating in this project please let Drs. Joseph or O’Hara know. The cases will be incorporated into the radiology rotation in BUSM 3.Congratulations to the following medical students!!
        • Anna Sofia Qvarfordt Eisenstein
        • Alexander James Gallan
        • Anunita Garg
        • Sandra Hsu
        • Hillary Ann  Johnston-Cox
        • Paul Romesser
        • Lev Vaisman
        • Bjorn Kristian Watsjold
    • Dr. Mark Flomenbaum was appointed Scientific Program Director and Moderator for the Semiannual Meeting of the National Association of Medical Examiners, held in conjunction with the American Academy of Forensic Sciences in late February.  The theme of the program was “The Negative Autopsy”.  Dr. Flomenbaum also delivered the first presentation
    • Martin Kroll, MD was interviewed for an article on Cardiovascular Markers which appeared in the March issue of CAP Today
    • Nader Rahimi, PhD was invited to join the editorial boards of two recently launched journals “ISRN Vascular Medicine” and “World Journal of Biological Chemistry”
    • Welcome to postdoc Sudha Natarajan, PhD who is newly working in the ITP Program within the Remick Lab. Sudha is a graduate from the Remick Lab out of the University of Michigan
    • Barbara Nikolajczyk, PhD was awarded a Boston Nutrition Obesity Research Center Pilot & Feasibility Program pilot grant entitled: “The Role of T cells in the Transition to Type 2 Diabetes”
    • Dr. Nikolajczyk will also serve as Chair of a block symposium at the Annual American Association of Immunologists meeting in San Francisco May 13-17
    • Martin Steffen, PhD and his team presented a poster about their project which aims to reduce the number of prostate biopsies: “Proteomics Of Peripheral Leukocytes In Patients With Elevated Serum Levels Of Prostate Specific Antigen” Martin Steffen, Agnes Bergerat, Mark Katz, David Wang, and Richard Babayan” at the Innovative Minds in Prostate Cancer Today (IMPaCT) Meeting, March 9–12, 2011. Orlando, Florida. According to Dr. Steffen this would alter, but not necessarily reduce billing by pathology :) (fewer slides to read, but a new test to administer and interpret)
    • Michael Roehrl, MD attended the National Cancer Institute Biospecimen Symposium (NCI BRN) in Bethesda, Maryland March 28 & 29, 2011. While there he chaired two Round Tables: “Ultra-Rapid Biobanking at Boston Medical Center” and “Biobanking for Next-Gen Proteomics and Metabolomics Research in Pathology.”
    • Barbara Nikolajczyk, PhD and Madhu Bogdan, PhD candidate in the Nikolajczyk Lab received a Laboratory Travel Award to attend the American Association of Immunologists Meeting May 13-17 2011 in San Francisco. It’ll pay 100% for both!

    Publications ACCEPTED:

    • Mostafa Belghasem, graduating Masters student and Dr. Joel Henderson recently finished writing a book chapter on “Kidney Structure and Physiology” for the CRC Handbook of Biomedical Engineering, 4th Edition.  It will be published in September 2011
    • Joel Henderson, MD has a publication accepted: Wyss HM, Henderson JM, Byfield FJ, Bruggeman LA, Ding Y, Huang C, Suh JH, Franke T, Mele E, Pollak MR, Miner JH, Janmey PA, Weitz DA, Miller RT. “Biophysical properties of normal and diseased renal glomeruli.” Am J Physiol Cell  Physiol. 2011 Mar;300(3):C397-405. PubMed PMID: 21123730
    • Dr. Nader Rahimi’s team has the following accepted for publication, this includes Sri Srinivasan, a current 3rd year PhD student: Meyer RD, Srinivasan S, Singh AJ, Mahoney JE, Gharahassanlou KR, Rahimi N. “PEST Domain Tyrosine and Serine Phosphorylation Controls Ubiquitination and Downregulation of VEGFR-2.”  Molecular and Cellular Biology, 2011
    • A second accepted publication from Dr. Rahimi, PhD: Boucher I, Kehasse A, Marcincin M, Rich C, Rahimi N, Trinkaus-Randall V. “Distinct Activation of Epidermal Growth Factor Receptor by UTP Contributes to Epithelial Cell Wound Repair.”  American Journal of Pathology, 2011
    • Michael Roehrl, MD has an article to be published in April 2011issue of Archives of Pathology and Laboratory Medicine.: Roehrl MHA, Lantz D, Sylvester C, Wang JY. “Age-Dependent Reference Ranges for Automated Assessment of Immature Granulocytes and Clinical Significance in an Outpatient Setting.”

    Publications-PUBLISHED:

    • Dr. Martin Kroll received a letter about a SAM-eligible education piece that he wrote, that read in part, “On behalf of the CAP Council on Education and the CAP SAM Committee, I would like to thank you for authoring the Archives Applied, SAM-eligible activity for your journal article titled, “Multiple Patient Samples of an Analyte Improve Detection of Changes in Clinical Status.” I am happy to advise you that this activity was released February 24th.”
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