Grand Rounds – Dr. David Holtzman
This month’s Grand Rounds featured Dr. David Holtzman, Barbara Burton and Reuben M. Morriss III Distinguished Professor of Neurology at Washington University in St. Louis. For the past 27 years, professor Holtzman has been leading research into understanding Alzheimer’s disease pathology and potential treatment options. Professor Holtzman has recently been investigating the role of sleep-wake cycle on amyloid-beta accumulation and subsequent Alzheimer’s disease progression. While discussing the very interesting research topic, Dr. Holtzman provided examples in which insights in pathology learned through basic science research can be applied to potential clinical therapy developments. We are thankful to Dr. Holtzman for showing a potential pathway for physician-scientists who wish to combine basic science and clinical translation.