Barry Horne

Horne, BarryPhD in Genetics and Genomics

BA, Florida Institute of Technology

Barry is a third year “Graduate Program in Genetics and Genomics”(GPGG) PhD student and a first year “Immunology Training Program” (ITP) pre-doctoral student, working in the Bonegio laboratory at the Boston University School of Medicine. His long-term interest is in performing translational research that focuses on the genetic causes of autoimmune diseases, with an ultimate goal of working towards better treatments and/or cures for autoimmune disorders such as Lupus and Anti-Phospholipid Syndrome (APS).

The Bonegio lab is investigating potential genetic causes and therapies for Lupus – particularly in the context of Lupus Nephritis. Barry is currently examining the roles of several different genes in induced “Immune Complex Glomerulonephritis” (ICGN). The goal of this research is to discover and define the genetic differences, transcriptional changes, and signaling pathway variations that favor or lead to the development of inflammation, proteinuria, and the overall ICGN disease state – so that the lab can then begin to search for ways to target them therapeutically.