Immunotherapeutics and Vaccinology

Investigations into methods to prevent or treat infections by vaccinations and the use of immune modulation modalities to attenuate autoimmune disease are currently being performed by a number of investigators in the Immunology Training Program. We look to develop improved adjuvants to enhance induction of protective immunity and examine responses to various antigens from pathogens in order to develop vaccination and vaccination strategies to protect humans from microbial diseases. Moreover, we have faculty who are interested in using a similar strategy to enhance protective responses to cancer. Finally, there is evidence that modulating the level or blocking the activity of certain immune mediators, like pro-inflammatory cytokines or cell adhesion molecules, can affect the response inpatients during sepsis or immune mediated diseases, which a number of faculty are also investigating.

Faculty involved in this research are: