Graduate Program Faculty

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Ruslan Afasizhev,  PhD
Specialization: Molecular mechanisms of RNA processing

Inna Afasizheva, PhD
Specialization: Mitochondrial gene expression, RNA editing, molecular biology

Rhoda Alani, MD
Specialization: Cancer biology, tumor biomarkers, epigenetic therapies for cancer
Specialization: Evidence-based protocols and standards in the field of biospecimen science.


Specialization: Orthotropic nude mouse models of non-metastatic and metastatic tongue cancer
Specialization: Women’s health, cancer prevention
Specialization: Lung Cancer
       Specialization: Gene regulation, biological mechanism of aging, chromatin architecture, transcriptional/epigenetic regulation
Specialization: Epidemiology of breast cancer
Specialization: Mitosis, transcription, chromatin structure
Specialization: Prenatal programming of brain development and aging by essential nutrient availability during gestation
Specialization: Pulmonary disorders and their connections to innate immunity, host-pathogen interactions, and inflammation
Specialization: Molecular mechanisms of hair growth and pathobiology of different forms of hair loss
Specialization: Developmental biology; embryonic pattern formation; systems biology
Specialization: Chronic kidney disease of undetermined etiology, increasing cessation among low-income smokers


Specialization: Computational biology and bioinformatics, identifying early drivers of lung cancer, therapeutic development and pathogenesis of COPD
Specialization: Evolution of development, insects, nematodes, developmental plasticity, behavioral plasticity, comparative genomics and transcriptomics, functional genetics
Specialization: Method innovation, leveraging natural language processing, machine learning/deep learning, and biostatistics, for biomedical and health research
Specialization: Mechanisms of post-transcriptional regulation during vertebrate embryogenesis using zebrafish as a model system
Specialization: DNA damage repair, histone modifications, genome stability in human cancer, and human developmental syndromes.
Specialization: Virus-host interaction
Specialization: Determining the structures and functions of biologically important polymers
Specialization: DNA identification and analysis of biological evidence


Specialization: Foundational and clinical genetics and genomics, graduate education, medical education, anti-racism, and equity & inclusion
Specialization: Molecular biology and cell biology techniques for the study of pathogenic viruses
Specialization: Ecological genomics, population genetics, molecular ecology, coral ecology, climate change, symbiosis
Specialization: Application, evaluation, and development of statistical methods for genetic, genomic and epidemiologic studies, including methods for genome-wide association studies (GWAS) and meta-analysis; methods for survival, correlated, and multivariate data; and modeling and clustering of temporal gene expression data
Specialization: BET bromodomains proteins, breast cancer, metabolic disease
Specialization: Statistical genetics
Specialization: Cellular and molecular mechanisms regulated by Wnt/ß-catenin signaling during embryonic organ morphogenesis, molecular mechanism leading to activation (stabilization and nuclear translocation) of ß-catenin
Specialization: Investigates how the human immune system as a tissue interacts with specific viral pathogens and ultimately regulates different outcome of infection
Specialization: Combines computational data analysis with novel experimental approaches and technologies to understand basic biological concepts in health and disease



Specialization: Fat cell differentiation
Specialization: Age-related macular degeneration, Alzheimer disease, gene mapping, genetic epidemiology, illicit drug dependence
Specialization: paramyxovirus genome transcription and replication mechanisms
Specialization: Cancer Therapeutics, tumor intravasation, zebrafish, MYC
Specialization: Mitochondrial physiology, mitochondrial genetic epidemiology, and cardiovascular disease
Specialization: Evolution of development, developmental genetics, phylogenetics, evolutionary genomics, invertebrate zoology; coral conservation
Specialization: Skeletal dysplasias in zebrafish
Specialization: Gene regulation;RNA processing; systems biology of co-transcriptional programs; computational genomics; role of gene architecture in cancer development and therapy
Specialization: Mechanisms regulating mammalian telomere maintenance and to understand how defects in this process contribute to premature aging and cancer progression
Specialization: Host-microbe interactions at the molecular, cellular and organismal level; mechanisms of bacterial transmission through stem-cell niche infection
Specialization: Mechanisms controlling the expression of immune genes


Specialization: Femtosecond laser ablation, neuronal damage, neuronal regeneration, C. elegans
Specialization: Computational biology, infectious diseases, mycobacterium
Specialization: High-resolution microscopy, genome-wide RNAi screening, cell biology, and bioinformatics, genome instability in human cancer
Specialization: Heterotrimeric G proteins, cytoplasmic factors that mimic the action of GPCRs
Specialization: Personalized therapy for AATDassociated liver disease via IPS modeling
Specialization: Biomaterials, drug delivery, macromolecular chemistry and engineering, nanodevices, tissue engineering
Specialization: New mechanisms of gene regulation by short RNAs and chromatin-modifying complexes, C. elegans
Specialization: Dendritic cells (DCs) in the initiation and propagation of HIV-1 replication


Specialization: Regulation of mammalian cell growth and cell cycle
Specialization: Prion Diseases, Alzheimer’s Disease
Specialization: Cellular mechanisms that regulate HIV replication and transcription
Specialization: Telomere alterations across a range of cancer types (e.g. prostate, breast, brain, pancreatic, ovarian)
Specialization:Thyroid gland development, thyroid hormone signaling and sensitivity
Specialization:  The relationship between neurotrauma and neurodegenerative diseases, with a primary focus on the blood-brain barrier and neuroinflammation
Specialization: Large-scale leanring, Bayesian inference, robust inference


Specialization: Innate immune system, sexually transmitted infections,


Specialization: Cytokines, pneumonia, posttranscription
Specialization: Bioinformatics, computational biology, epidemiology, genetics, neurology, ophthalmology, statistics


Specialization: Insulin action; Adipocyte biology; Membrane traffic
Specialization: Stem cell biology, iPS cells, reprogramming, gene therapy, lung developmental biology
Specialization: Tuberculosis
Specialization: Regulatory mechanisms underlying the interactions between the metabolic pathway of protein N-glycosylation and intercellular adhesion in tissue development and disease
Specialization: Tuberculosis
Specialization: Maladaptive neural plasticity in addictive processes and brain disorders


Specialization: Genomics characteristics of neurodegeneration in human tissue using bioinformatics and machine learning approaches
Specialization: Biology of aging and understanding the basic mechanisms that underlie the pathogenesis of age-related diseases
Specialization: Molecular and cellular biology of melanocyte stem cells and melanoma
Specialization: PIWI Subfamily of Argonaute Proteins, Piwi-interacting RNA
Specialization: Uncovering the role of the genetic mutations in the extracellular matrix protein ACLP/AEBP1 in Ehlers-Danlos Syndrome and connective tissue diseases.
Specialization: Computational approaches to leverage genome-wide datasets (especially genome-wide gene-expression) for clinical and biological insight
Specialization: CLL; Leukemia; Lymphoid malignancies; Sarcoma; Breast cancer; cAMP signaling
Specialization: Computational biology and cancer bioinformatics; serving the BUSM Data Science Core
Specialization: Stress signaling and cell wall biogenesis in fungi
Specialization: Development of statistical and computational approaches for genetics/genomics and bioinformatics studies
Specialization: Chemical basis of pathogen and host interactions, and the chemical nature of the biological clock
Specialization: Psychiatric and neurological disorders including panic disorder, post-traumatic stress disorder, and Alzheimer’s disease
Specialization: How cytoskeletal dynamics are regulated to drive cell motility in both normal and pathological conditions
Specialization:  Chronic kidney disease, kidney and urinary tract development
Specialization: Statistical problems and study design and analysis issues in human genetics, particularly in the mapping of complex genetic diseases


        Specialization: Regulation of protein synthesis and the Integrated Stress Response (ISR)
Specialization:  Hematology, stem cell biology, mechanism of cell differentiation
Specialization: Thyroid hormone signaling, ChREBP transcription factor
Specialization:  Molecular events associated with the progression of premalignant squamous lung lesions for targeted chemoprevention
Specialization:  Drosophila developmental biology, cell death, oogenesis
Specialization:  Immunology in the lung and its influence on acute lower respiratory tract infections
Specialization: Development of machine learning and knowledge discovery methodologies, probabilistic reasoning and Bayesian approaches to modeling biomedical data
Specialization: Molecular mechanisms of AL amyloidosis with the aim of developing new treatments for this disease
Specialization: Stem cells, gene transfer, lentiviruses, hematopoietic stem cells, induced pluripotent stem cells
Specialization: Molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses,  BSL4 work, virus-host interaction
Specialization: Developmental hematopoiesis;  The generation, culture, and directed differentiation of pluripotent stem cells;  The generation, culture, and directed differentiation of pluripotent stem cells; Pluripotent stem cell-based modeling of hematopoiesis: a Platform for Production of Transfusable Human Blood Cells; Pluripotent Stem Cell Modeling of Human Disease: The ‘Clinical Trial in a Test Tube’: Sickle Cell Anemia; Amyloidosis


Specialization: Cardiac development and disease, muscle regeneration, muscular dystrophy, mouse developmental biology, gene regulation



Specialization: Cancer epidemiology, health disparities, breast cancer subtypes
Specialization: Statistical genetics, complex cardiovascular traits, exome and whole genome
Specialization: Transcriptional and non-transcriptional functions of various cofactors with a particular focus on their misregulation during disease states such as cancer, diabetes and other inflammatory disorders
Specialization: Computational method development, noncoding variants in neurological development and disease



Specialization: Cell signaling in particular in receptor tyrosine kinases, protein modification; Mouse and cell culture-based angiogenesis and tumor models
Specialization: Mechanisms that regulate lineage commitment and the subsequent steps of cellular maturation of bone marrow cells into polyploid megakaryocytes
Specialization: Immunobiology of Trauma
Specialization: Immunology; Autoimmunity; Systemic lupus erythematosus; and Nephrology
Specialization: Alzheimer’s genomics
Specialization:Molecular biology and genetics, hypertension, learning and memory
Specialization: Dysregulated Plasticity of the Nervous System


Specialization: Virology; Identifying and characterizing host proteins that are cleaved by viral proteases
Specialization: Pathogenesis of human immunodeficiency virus type 1 heterosexual transmission
Specialization: Incorporates techniques from behavioral ecology, morphometrics, and genomics across the Order Primates and in vervet monkeys (Chlorocebus spp.)
Specialization: Role of inflammation on aortic smooth muscle cell function
Specialization: Systems biology, evolution of biochemical networks, genomics, metabolic engineering, microbial ecology
Specialization: Neurodevelopment, cardiovascular development in rare multi-systemic disorders
Specialization: molecular mechanisms of skin development, with particular emphasis on the regulation and maintenance of adult stem cells in the skin; Dissecting the signal transduction pathways which regulate stem cell quiescence to better understand how alterations in these signaling pathways contribute to melanoma and non-melanoma skin cancers; Studies a role of higher-order chromatin organization in the process of pigmentation
Specialization: How common environmental pollutants adversely affect the growth and behavior of several different types of normal and malignant cells
Specialization: Design and analysis of genetic association studies of complex disease
Specialization: systems biology of the immune and inflammatory systems, gene regulation in immune and inflammatory systems, inflammatory diseases, transcriptional networks, DNA-binding of transcription factors and transcriptional regulatory complexes, computational genomics, cis-regulatory logic in transcription
Specialization: Regulation of IFN-gamma and cytotoxic effector functions by CD8+ T cells
Specialization: Gene expression profiling, lung neoplasms, pulmonary disease, computational biology
Specialization: Evolutionary genetics, ecological genetics and genomics, biodiversity genomics, beetles
Specialization: Ebola, Marburg, and other hemorrhagic fever viruses



Specialization: Fate, heterogeneity, and single-cell analyses of microglia and astrocytes in neurodegeneration, traumatic brain injury, and brain tissue repair; neuroimmunology,      neurodevelopment
Specialization: Human induced pluripotent stem cells for Alzheimer’s disease (AD) genetics and in vitro drug screening
Specialization: Cancer genetics, epigenetics, signaling pathways, SMAD genes
Specialization: protective immunity, systems-level analysis, systems immunology, AI
Specialization: Wound response and repair of epithelium, neurons and extracellular matrix
Specialization: Molecular and cellular mechanisms that regulate ECM synthesis in healthy tissues and in pathological conditions such as fibrosis and tumorigenesis



Specialization: Hippo signaling pathway, YAP/TAZ, Cell polarity, cancer biology
 Specialization: Co-factors that influence the mucosal transmission of HIV-1; the role of endogenous nucleic acid autoantigens as mediators of systemic lupus erythematosus


Specialization: Electrophysiology, calcium imaging, single-cell sequencing, basal ganglia circuitry and motivated behavior
Specialization: Public health genomics, health communication/e-health, health literacy, and cancer prevention and control
Specialization: Molecular endocrinology and cell signaling; Cancer gene therapy and pharmacology; Liver genes and transcriptional control; Orphan receptors and responses to foreign chemicals
Specialization: Alpha-1 antitrypsin deficiency, COPD pathogenesis, gene therapy, pluripotent stem cells
Specialization: Pathophysiology of neurodegenerative diseases, including Alzheimer’s disease, Amyotrophic Lateral Sclerosis and Parkinson’s disease
Specialization: Synthetic and systems biology in immune cell
Specialization: Pair imaging-based and genomic measurements of gene expression with statistical and physically based computational models to explore questions of gene regulatory network function in Drosophila




Specialization: Glycomics, glycosaminoglycan expression, bioinformatics, glycosaminoglycans
Specialization: Signal transduction and epigenetic mechanisms underlying CNS disorders.
Specialization:  Reduction of the accumulation of neurotoxic amyloid beta (Abeta). Alzheimer’s disease and aging, neuroprotection, and klotho transcriptional regulation.
Specialization: Stem cell and genomics; serving the BUSM Data Science Core
Specialization: Genetic and epigenetic studies of substance use disorders (SUDs) and related psychiatric disorders and traits
Specialization: Biomedical Genetics; genetic risk factors of complex human diseases and identifying underlying functional mechanisms.

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