The students of the GPGG are a diverse group. Each has a strong background in research and helps support the strong community and learning environment.
Gian Sepulveda (Grishok Lab)
Gian is a third-year GPGG PhD student in the lab of Dr. All Grishok. The Grishok lab is currently working on MYC regulation in the context of triple negative breast cancer, as well as the epigenetic regulation of the histone 3 lysine 79 methyltransferase DOT1L. Gian’s project focuses on a putative MYC cleavage that might be essential in MYC-target gene regulation. Preliminary data suggests that MYC may be cleaved to either a 27 or 35 kDa protein. His plans after completion of the PhD are toward science communication and teaching, with a particular interest in journal editing.
George Chen (Dries Lab)
George is a second year student in GPGG working in the lab of Ruben Dries in the department of Hematology Oncology. The lab focuses on spatial transcriptomics and how this technology can be applied to understand the mechanisms and heterogeneity of triple negative breast cancer. In his free time, George enjoys listening to music and drawing.
David Engel (Waxman Lab)
David is a second year PiBS student that just joined the GPGG program. He is a member of Dr. Waxman’s lab on the Charles River Campus. David’s project is focused on the effects of long term exposure to xenobiotics on the epigenetic and expression landscape of PCGs and lncRNAs. His hobbies include creating things through drawing, digital painting, and wood carving. At the same time, David likes pushing his physical limits with boxing, enjoying a good sparring match, and working out.
Taylor Matte (Hawkins Lab)
Taylor is a third year PhD Candidate in the Hawkins Lab at the Center for Regenerative Medicine (CReM). In his thesis work, he seeks to use an iPSC-based multi-omic approach to construct a roadmap of airway development. Outside of the lab, Taylor serves on the BU Anti-Racism Taskforce, where he teaches in the MedSci program seeking to increase equity in STEM education. He also enjoys sensory deprivation tanks, themed parties, and Björk.
Megan Snyder (Sherr Lab)
Megan is a third year GPGG PhD candidate in the laboratory of Dr. David Sherr. The primary focus of the Sherr lab is to understand the immunological and molecular mechanisms that influence cancer risk through the interactions between the aryl hydrocarbon receptor (AhR) and both environmental and endogenous ligands. Her project involves understanding the role of the AhR as a driver of both tumorigenesis and immune suppression in lung and oral cancers by elucidating the genetic and phenotypic consequences of the AhR>IDO>Kyn>AhR ligand amplification loop. This research, in conjunction with data from the Precancer Genome Atlas, aims to identify a genetic signature indicating—but prior to—tumor development when AhR inhibitors can be administered to intercept and prevent cancer. Megan’s broader interests include gene therapy, translational research, and a passion for developing novel treatments that utilize personalized and preventative medicine. Outside of the lab, she enjoys keeping up her circus skills, playing soccer, competing in bar trivia, and binging good TV shows.
Dylan Steiner (Lenburg Lab)
Dylan Steiner is a 2nd year student in the Genetics & Genomics PhD program at Boston University School of Medicine in the lab of Marc Lenburg and Avi Spira and the lab of Jennifer Beane. His current research interests are on lung cancer subtype biology, premalignancy, and development of lung cancer biomarkers for early detection and precision medicine. Dylan enjoys live music, surfing (when in his home state of California) and nurturing his houseplants.
Robert Fisher (Alani Lab)
Robert is a second year GPGG PhD candidate in the lab of Dr. Rhoda Alani. Robert’s project aims to better understand the role of transcriptional repressor complexes in metastatic, therapeutic-resistant melanomas. He is currently using xenograft systems, epigenetic therapies, and a multi-omic approach to elucidate the overarching connection between the CoREST complex, epithelial-mesenchymal transition, and melanoma. Outside of the lab, Robert enjoys browsing Bandcamp for music ranging from jazz to techno, cooking and trying new foods, reading, fermenting, and listening to comedic podcasts.
Junxiang Xu (Dries Lab)
Junxiang is a second year GPGG PhD candidate. He is co-mentored by Dr.Ruben Dries and Dr. Joshua Campbell. His research will be focusing on spatial omics and single-cell sequencing on prostate cancer, as well as the application of data analysis software related to them. In Junxiang’s spare time, he likes hiking and other outdoor activities.
Thomas Liontis (Grishok Lab)
Thomas is a second-year GPGG PhD student in Dr. Alla Grishok’s lab. He is currently working on dissecting pathways of RNA interference regulated by the histone methyltransferase DOT-1.1 in C. elegans. He will perform RNA sequencing to further characterize dot-1.1 mutants. When not confining himself to the lab, Thomas can be found playing table tennis, performing some musical instrument, or walking with his wife around the Public Garden.
Hanna Barlit (Labunsky Lab)
Hanna Barlit is a second year student in the lab of Dr. Labunskyy in the department of Dermatology. The lab research interest is to investigate transcriptinal and translational changes during aging utilizing high-throughput sequencing in combination with biochemical approaches. Hanna’s project is mainly focused on studying an interplay between iron regulation and a cell cycle in context of aging. Outside of the lab, Hanna enjoys long walks with her husband and cooking together.