GPGG Core Courses

Integrated Core Curriculum: Foundations in the Biomedical Sciences

Full details about the integrated curriculum can be found online here and here.

Principles of Genetics & Genomics

GMS GE 701, 4 credits
Fall Semester

This course will serve as a foundation for understanding the heritable basis of numerous biological traits, the relationships among genes, and the regulation of their expression. We will focus on the ability to use genetic systems to probe these problems and therefore will heavily explore the experimental aspects of these investigations. In addition, we will discuss the impact of the genome sequences on the practice of modern science. Moreover, we will use a case study approach to investigate the rich variety of scientific insights gained through genetic studies of aging, addiction, obesity, and others.

Structure and Function of the Genome

GMS FC 712, 2 credits
Fall Semester

The second module of the Foundations in Biomedical Sciences course will focus on the mechanisms of biological processes that influence the inheritance, regulation, and utilization of genes. Genetic and genomic, molecular, cell biological, and biochemical experimental approaches to understanding these processes will be explored. In addition, we will discuss the possibilities of utilizing these technologies in medical treatments. This course is part of a series of four core integrated courses and additional elective courses aimed towards first year Ph.D. students in the Division of Graduate Medical Sciences. The four cores will be integrated in content and structure, and therefore are intended to be taken as a complete, progressive sequence.

Genetics and Genomics Colloquium

GMS GE 713 and 704, 2 credits each
Fall and Spring Semesters

The Genetics and Genomics Colloquium will be a highly participatory journal club where the students will be asked to give presentations on cutting edge research with the focus on communication skills in addition to scientific content. This approach will allow students to become more comfortable with public speaking while developing the skills necessary for effective communication of scientific ideas.

Translational Genetics and Genomics

GMS FC 715, 2 credits
Spring Semester

Modern human genetics has evolved at a tremendous pace, with the promise of an affordable complete genome sequence for every individual just around the corner. While the raw information has increased exponentially, its translation to patient care has not kept pace. We will discuss exciting recent advances in human genetics and genomics, with illustrative examples of their translation into improvements in diagnosis and treatment of patients. We will also discuss the ethical and societal challenges of this rapidly evolving field. Our course is aimed at first or second year Ph.D. students, and will be taught by faculty in a variety of departments through traditional lectures and discussion sections. Students will be evaluated on their ability to explain the translational research process and demonstrate how individual research findings build on one another to move a field forward to ultimately impact patient care.


(Four credits, Second Year)

Fall Semester

Human Genetics, GMS MS 781, 4 credits

Cellular Aspects of Development and Differentiation, GRS BI 610, 4 credits

Computational Biology: Genomes, Networks, Evolution, ENG BE 562, 4 credits

Genetics and Epidemiology of Disease, GMS MM 701, 2 credits

Comprehensive Immunology, GMS MI 713, 4 credits

Cancer Biology and Genetics, GMS MM 703, 2 credits

Pharmacogenomics, GMS PM 832, 2 credits

Protein Structure and Function, GMS BI 783, 2 credits

Molecular Mechanisms of Growth and Development, GMS BI 787, 2 credits

Receptors and Signal Transduction, GMS BI 790, 2 credits

DNA and Protein Sequence Analysis, ENG BE 561, 4 credits

Gene Regulation and Pharmacology, GMS PM 880, 2 credits

Molecular Basis of Neurological Disease, GMS MS 783, 2 credits

Systems Neuroscience, GMS AN 810, 4 credits

Spring Semester

Gene Targeting in Transgenic Mice, GMS BI 776, 2 credits

Biochemical Mechanisms of Aging, GMS BI 786, 2 credits

Mass Spectrometry and Functional Genomics, GMS BI 793, 2 credits

Elementary Biostatistics, GMS MS 700, 2 credits

Genetics of Microorganisms, GMS MI 714, 4 credits

Growth Control and Cell Transformation, GMS MI 717, 4 credits

Teaching Methods in the Biomedical Sciences, GMS AN 804, 2 credits

Technology Commercialization: From Lab to Market, MET AD 893, 4 credits

Mechanisms and Models of Cellular Regulation, ENG BE 700, 4 credits

Genetics, Ethics, and the Law, GMS BT 440, 4 credits

Technology Commercialization: From Lab to Market, MET AD 893, 4 credits

Neuroanatomical Basis of Neurological Disorders, GMS AN 808 ,2 credits

Cognitive Neuroscience, GMS AN 811, 4 credits