Pathology & Laboratory Medicine News Items – Winter 2017/2018

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February 1st, 2018

Pathology & Laboratory Medicine News Items – Winter 2017/2018

 

  • Announcements:
      • Nancy S. Miller, M.D. presented “A point of view about point of care testing for diagnostic microbiology in the U.S.” at the Global Applied Microbiology Conference, October 18-19, Toronto, Ontario, Canada, and
      • Dr. Miller presented also as ASM Distinguished Lecturer at the Southern California Branch-American Society for Microbiology, October 27-28, La Jolla, CA.
      • Also at La Jolla, Dr. Miller was invited to a breakout Educators’ Session and presented, “Clinical Microbiology at the Crossroads: A Potpourri of Challenges and Lessons Learned in this Era of Evolving Technology”
      • Residents Mahmoud Soliman, MD (presenter) and Israa Laklouk, MD (author) got an Honorable Mention for abstract titled “Predictive Accuracy of Thyroseq V2 for Malignant Thyroid Nodules among Bethesda-III Cytology Subcategories: Atypia of Undetermined Significance (AUS) And Follicular Lesion of Undetermined Significance (FLUS)” in Twelfth Annual MMS Research Poster Symposium for Residents, Fellows and Medical Students (Clinical Research category)
      • Dr. Mostafa Belghasem’s work was featured on the front cover of “Science Translational Medicine” Vol 9 Issue 417 (Nov. 22. 2017) titled: Cover story: Anticoagulation strikes a balance Sample cover image attached if you would like to check it out: http://stm.sciencemag.org/content/9/417
      • Dr. Susan Winandy has received new grant funding:  “Defining programs of gene expression regulated by Ikaros in T cells” NIH/NIAID, R03
      • Dr. David Kindelberger reports “we had our first meeting of the new Medical Student Pathology Interest Group right before the holidays.  This officially sanctioned student group has as its mission to provide medical students with increased exposure to all areas of pathology through a variety of activities.  We had 17 medical students participate in our initial meeting and tour.  Dr. Carmen Sarita-Reyes has been instrumental in bringing this together, as have students Natalie Rizzo, Gabriel Lerner, and Brad Zehr.  Stay tuned for more news!
      • Dr. Artem Shvetsov will be joining our residency program at the end of January. Artem received his MD and PhD (in Pathology and Cell Biology) in Russia and has extensive research experience in molecular virology.  He is well-known to the department, having done an observership here. Artem lives in Arlington with his family. Please join us in welcoming Artem to the department!
      • Artem Shevtsov Pic
      • Dr. David Sherr gave a talk at Memphis University in November titled “An Environmental Chemical Receptor that Controls Multiple Contributors to Cancer Aggression”.
      • Dr. Sherr also gave a talk at the National Academy of Sciences the first week of January 2018 entitled “tracking an AHR regulatory circuit in cancer with AHR inhibitors, CRISPR/Cas9 knockdown, and other tricks”
      • Dr. Shinichiro Kurosawa has been re-appointed as a voting member to the Boston University Laboratory Safety Committee Space / Infrastructure Subcommittee through December 2019
      • Two Mallory Fund Projects have been awarded:
            • Summer Pathology Fellowship – Carmen Sarita-Reyes, M.D.
            • Using comparative pathology to develop “one medicine-one pathology” competencies for pathology residents – Nicholas Crossland, D.V.M., Nancy Miller, M.D., and David Kindelberger, M.D.
      • Bravo to Morgan Thompson, recent MS Graduate, her abstract has been accepted for presentation in a Poster Session at the American Association for Cancer Research (AACR) Annual Meeting, April 14-168, 2018 in Chicago, Illinois, and the piece will be published in the 2018 Proceedings of the AACR; “Effect of preanalytic variables on established and emerging thrombosis-related biomarkers in an ethnically and racially diverse population of cancer patients and healthy subjects at a safety net hospital” Morgan P. Thompson1, Elizabeth R Duffy1,2, DJ Stearns-Kurosawa2, Jasmin Bavarva3, Shinichiro Kurosawa2, Jiyoun Kim2, Cheryl Spencer1, Daniel Remick1,2, Mark Sloan1,2, Joel Henderson1,2, Kerrie P Nelson2, Joseph Y Tashjain2, Yibing Wei2, Rachana Agarwal3, Michelle A. Berny-Lang4, Chris Andry1,2
  • Publications PUBLISHED:
    • Martin Peter Steinbuck, Ksenia Arakcheeva and Susan Winandy; “Novel TCR-mediated mechanisms of Notch activation and signaling” The Journal of Immunology. 2017. Dec 29. pii: ji1700070. doi: 10.4049/jimmunol.1700070. [Epub ahead of print]
    • N. Rahimi. Defenders and Challengers of Endothelial Barrier Function. Front Immunol. 2017 Dec 18;8:1847. doi: 10.3389/fimmu.2017.01847. eCollection 2017. https://www.frontiersin.org/articles/10.3389/fimmu.2017.01847/full
    • Ho RX, Meyer RD, Chandler KB, Ersoy E, Park M1, Bondzie PA, Rahimi N, Xu H, Costello CE, Rahimi N. MINAR1 is a Notch2-binding protein that inhibits angiogenesis and breast cancer growth.  J Mol Cell Biol. 2018 Jan 10. doi: 10.1093/jmcb/mjy002. [Epub ahead of print https://academic.oup.com/jmcb/advance-article/doi/10.1093/jmcb/mjy002/4796960
    • Rosana D Meyer,, Xueqing Zou, Marwa Ali, Esma Ersoy, Philip Apraku Bondzie, Mehrdad Lavaei, Ilya Alexandrov, Joel Henderson and Nader Rahimi. TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer. Oncotarget Dec. 2017 http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=23822&path[]=74949
    • Moshe Shashar, Mostafa Belghasem*, Shinobu Matsuura, Joshua Walker, Sean Richards, Faisal Alousi1, Keshab Rijal, Vijaya B. Kolachalama, Mercedes Balcells, Kazuo Nagasawa, Joel M. Henderson, Amitabh Gautam, Jean Francis, Kumaran Kolandaivelu, David H. Sherr, Katya Ravid, Vipul C. Chitalia. “Targeting uremic thrombosis axis normalizes hyperthrombotic phenotype without increasing the bleeding risk.” Science Translational Medicine, Sci Transl Med. 2017 Nov 22;9(417). pii: eaam8475. doi: 10.1126/scitranslmed.aam8475 *= First co-author
    • Vijaya B. Kolachalama, Priyamvada Singh, Christopher Q. Lin, Dan Mun, Mostafa Belghasem, Joel M. Henderson, Jean M. Francis, David J. Salant, Vipul C. Chitalia “Association of pathological fibrosis with renal survival using deep neural networks.” Kidney International Reports, Nature. Kidney Int Rep (Jan. 11. 2018); https://doi.org/10.1016/j.ekir.2017.11.002
    • Vijaya Kolachalama, Moshe Shashar, Faisal Alousi, Sowmya Shivanna, Keshab Riajl, Mostafa Belghasem, Joshua Walker, Shinobu Matsuura, Gary Chang, C Michael Gibson, Laura Dember, Jean Francis, Katya Ravid, Vipul C. Chitalia. “Uremic solute-Aryl Hydrocarbon Receptor -Tissue Factor Axis Associates with Post-Vascular Injury Thrombosis in Humans.” Journal of the American Society of Nephrology; J AmSoc Nephrol 29: ccc–ccc, Jan. 17. 2018. doi: https://doi.org/10.1681/ASN.2017080929
    • Ritter, JL & Genco, GA. Neisseria gonorrhoeae–Induced Inflammatory Pyroptosis in Human Macrophages is Dependent on Intracellular Gonococci and Lipooligosaccharide. Journal of Cell Death http://journals.sagepub.com/doi/abs/10.1177/1179066017750902