The Role of Urate in Knee Osteoarthritis-Related Inflammation, Pathology and Pain

Treatments for OA of the knee remain limited. There are some compelling data to suggest that urate, a causative factor in gout, may also play a role in OA. This research study aims to find out if urate may be linked to inflammation in OA, structural damage in OA, and the fluctuating nature of pain in OA. If tehre is a link, then it would mean that urate-lowering treatments may be a therapeutic option to study for management of knee OA.

PI: Tuhina Neogi
Funded by NIAMSK24 AR070892. Funding period: 2017-2022