Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

Gout is a common inflammatory arthritis for which the mainstay of treatment is urate-lowering therapy. Allopurinol and febuxostat are the two most commonly prescribed medications for gout, but whether they are equally effective at properly used doses is not known. This randomized clinical controlled trial aims to find out if both drugs have similar effects on lowering serum urate and flare rates. These results will help clinicians choose the most appropriate therapy for their patients with gout.
Executive Steering Committee member: Tuhina Neogi
Funded by VA CSP594. Funding period 2015-2020