Researchers Develop Improved Measure of Genetic Risk for Alzheimer’s Disease
August 27, 2026 Boston University researchers, including Framingham Heart Study Brain Aging Program investigator Lindsay A. Farrer, PhD, have developed and validated a new multi-ancestry polygenic risk score (PRS) for Alzheimer’s disease that improves risk prediction across diverse ancestral populations. The study, published in Nature Genetics, used genetic data from diverse populations to create a […]
Asian Cohort for Alzheimer’s Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer’s disease among Asian Americans and Canadian
Abstract Introduction: Clinical research in Alzheimer’s disease (AD) lacks cohort diversity despite being a global health crisis. The Asian Cohort for Alzheimer’s Disease (ACAD) was formed to address underrepresentation of Asians in research, and limited understanding of how genetics and non-genetic/lifestyle factors impact this multi-ethnic population. Methods: The ACAD started fully recruiting in October 2021 with one […]