Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer’s disease

Jun GR, Zhu C, Chung J, Panitch R, Hu J, The Alzheimer’s Disease Genetics Consortium, Foroud TM, Wang L-S, Ertekin-Taner N, Bennett DA, Haines JL, Mayeux RP, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Protein phosphatase 2A, complement component 4, and APOE genotype linked to Alzheimer disease using a systems biology approach. Alzheimer Dement 2022; 18:2042-2054.