Selected Publications

PUBLISHED COVER
Jacob et al. Cell Stem Cell 2017

See a comprehensive Pubmed listing of our publications.

  1. Killian Hurley, Jun Ding et al. Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors. Cell Stem Cell. Jan, 2020.

    Click for pdf: Hurley et al 2020

  2. Laertis Ikonomou et al. The in vivo Genetic Program Of Murine Primordial Lung Epithelial Progenitors. Nature Communications.  Jan, 2020.

    Click for pdf: Ikonomou et al 2020

  3. Jacob A, Vedaie M, Roberts DA, Thomas DC, Villacorta-Martin C, Alysandratos KD, Hawkins F, Kotton DN. Derivation of self-renewing lung alveolar epithelial type II cells from human pluripotent stem cells. Nature Protocols. Dec, 2019; 14:3303-3332.

Click for pdf: Jacob et al 2019

4. Jacob A et al. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.   Cell Stem Cell. Oct 5, 2017  PMID: 28965766.

Click for pdf: Jacob et al 2017

5. Hawkins F, Kramer P, Jacob A, Driver I, Tomas DC, McCauley KB, Skvir N, Crane AM, Kurmann AA, Hollenberg AN, Ngyen S, Wong BG, Khalil AS, Huang SXL, Guttentag S, Rock JR, Shannon JM, Davis BR, Kotton DN. Prospective Isolation of NKX2-1 Expressing Human Lung Progenitors Derived from Pluripotent Stem Cells. Journal of Clinical Investigation. May 2, 2017. doi: 10.1172/JCI89950. PMID: 28463226

Click for pdf: Hawkins et al JCI 2017

6. McCauley KB, Hawkins F, Serra M, Thomas DC, Jacob A, Kotton DN. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017 Mar 22. PMID: 28366587. PMID: 28366587 .       

Click for pdf: McCauley et al 2017

7. Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean JC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN, Kotton DN. Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 2015 Nov 5;17(5):527-42. doi: 10.1016/j.stem.2015.09.004. Epub 2015 Oct 22.PMID: 26593959

8. Longmire T.A., Ikonomou L., Hawkins F., Christodoulou C., Cao Y., Jean J.C., Kwok L.W., Mou H., Rajagopal J., Shen S.S., Dowton AA, Serra M, Weiss DJ, Green MD, Snoeck HW, Ramirez MI, Kotton DNEfficient derivation of purified lung and thyroid progenitors from embryonic stem cells. Cell Stem Cell. 2012;10:398–411.