2014 Research Symposium

August 15th, 2014 in Recent News

Save the Date!

The Genome Science Institute 2014 Annual Research Symposium will be Wednesday, November 5, 2014 in the Hiebert Lounge from 12-5 PM.
Poster Session: Poster presentations are open to all Boston area researchers including undergraduate students, graduate students, postdoctoral fellows and faculty.
Oral Presentations: Presenters will be invited from abstracts submitted by undergraduate and graduate students, and postdoctoral fellows.
Awards: Prizes will be given for top student and postdoctoral posters and presentations.
Genetics and Genomics Graduate Studies at BU: Representatives from BU graduate programs that provide training in Genetics and Genomics will be available.

Vendor Tables: Representatives from companies providing Genetics and Genomics related products and services will present their latest technology.

Additional information, including how to submit an abstract, will be available here.

Contact gsi@bu.edu with questions

We look forward to seeing you on November 5!

Introduction to the Globus Genomics GSI Site License

July 21st, 2014 in Recent News

On July 24th, the Genome Science Institute is hosting a seminar to introduce the new Globus Genomics site license. Globus Genomics is a computing platform for next generation sequencing data analysis and management. This seminar will introduce the functionality of this resource and provide details on the scope of the license and how to access it.


The seminar is being held in L311 in the Instructional Building from 11AM-12:30PM.


A copy of the flyer is available here.

Sixth Annual Genome Science Institute Seed Grant Award Recipients

May 21st, 2014 in Recent News

The BUMC Genome Science Institute (GSI), established in 2008, fosters collaboration and serves as a resource for Boston University investigators engaged in genetics and genomics research and education. The GSI is pleased to announce the recipients of the sixth annual GSI Seed Grant Award.

Of nine applications, the following recipients were selected following peer review of the proposals.


1. “Epigenetic Variation in Opioid-Exposed Mother-Infant Dyads”

Elisha Wachman, PhD

Boston University School of Medicine

Department of Pediatrics


Alice M. Wang, PhD

Boston University School of Medicine

Department of Pediatrics


Kelley Saia, PhD

Boston University School of Medicine

Department of Obstetrics and Gynecology


2. “Epigenetic Prediction of Insulin Resistance”

Barbara S. Nikolajczyk, PhD

Boston University School of Medicine

Departments of Medicine and Microbiology


Maria I. Ramirez, PhD

Boston University School of Medicine

Department of Medicine and Department of Pathology and Laboratory


3. “Role of the NCoR corepressor complex in the development of insulin resistance”

Valentina Perissi, PhD

Boston University

Department of Biochemistry


Stefano Monti, PhD

Boston University

School of Public Health

Department of Biostatistics


GSI Seed grants are intended to support:

The expansion of research at Boston University by supporting new collaborations between groups with diverse expertise to address an important scientific question in genetics and genomics research.

Development of new and emerging areas of genetics and genomics research.

The GSI Seed Grant Committee and GSI Directors thank the applicants and reviewers who participated in this process and look forward to continued growth in genetics and genomics research at Boston University.

Please contact the GSI at gsi@bu.edu with questions or with your ideas on how the GSI can better facilitate or develop genetics and genomics research at BU.

RNA-seq data analysis workshop scheduled for April 28th

April 16th, 2014 in Recent News

Please click here to go to the workshop webpage.

Registration for the RNA-seq hands-on workshop is closed

December 2nd, 2013 in Recent News

Please click here to go to the workshop webpage.

Newly Endowed Chair in Human Genetics

November 26th, 2013 in Uncategorized

Applications are now being accepted for  a new endowed professor position, the Aubrey Milunsky Professor of Human Genetics.  Please click here for more information on how to apply.

GSI Next Generation Sequencing Mini Symposium

December 3rd, 2012 in Uncategorized

The Next Generation Sequencing Mini-Symposium held on Thursday, November 29, 2012 was a huge success with a large turnout and quality presentations focusing on mRNA-seq, sncRNA-seq, and ChIP-seq.  The following is a list of presenters with a link to their presentation slides.

1:00 pm Rick Myers (GSI Director) - Introduction and Overview


1:10 pm Rebecca Kusko (Spira Lab) – mRNA sequence analysis


1:35 pm Alexandra Dumitriu (Myers Lab) – mRNA quality control methods


2:05 pm Andi Broka (LinGA System Administrator) - Computational resources (LinGA use)

BROKA_Comp. Resources for Next Gen Sequence Analysis

2:45 pm Elyse Kozlowski (Jones Lab) – Sample and library prep for miRNA

KOZLOWSKI_GSI sequencing talk final

3:10 pm Josh Campbell (Spira Lab) – Analytic strategies for miRNAs


3:35 pm Evan Johnson (Computational Biomed) – Analytic strategies part II


4:00 pm Antonio Luiz (Galagan Lab) - Studying Transcription factors by ChIP-seq


4:30 pm Rick Myers (GSI Director) - Studying Histon marks by ChIP-seq

GSI Research Symposium Winners

November 15th, 2012 in Uncategorized

Click to Enlarge

Standing: Rebecca Kusko, Zachary Hunter, Carly Garrison, Artie Lambert, Anna Lyubetskaya, Joshua CampbellSitting: Kahkeshan Hijazi and Hilo Milo Rasouly  Missing: Kristen Ott, Sarah Heerboth, and Ying Shen

At the Genome Science 2012 Research Symposium awards were given to graduate students and post doctoral fellow for oral and poster presentations.  The following is a list of winners:

Oral Presentation Winners:

Arthur Lambert (Graduate Student in Molecular Medicine, Thiagalingam Lab) - Periostin signaling regulates breast cancer stem cells

Anna Lyubetskaya (Graduate Student in Bioinformatics, Galagan Lab) - Using ChIP-seq for transcription factor binding sites prediction and validation in M. tuberculosis

Hila Milo Rasouly (Graduate Student in Genetics and Genomics, W. Lu Lab) - Loss of Robo2 improves survival of ILK mutant mice

Kristen Ott (Graduate Student in Genetics and Genomics, Navarro Lab) - Characterizing spindle-E, a protein involved in guarding the genome

Zachary Hunter (Graduate Student in Pathology and Laboratory Medicine, Treon Lab) - Copy number and small variant analysis from whole genome sequencing of 30 patients with Waldenstrom’s Macroglobulinemia

Poster Presentation Winners:

Joshua Campbell (Postdoctoral Fellow, Spira Lab) - Characterizing the small RNA transcriptome associated with COPD and ILD using next generation sequencing

Carly Garrison (Graduate Student in Genetics and Genomics, Spira Lab) - Mir-4423 promoted ciliated cell fate during airway epithelium differentiation

Sarah Heerboth (Undergraduate Student in Biology) - Development of a combination therapy:  Allele-specific re-expression of an imprinted tumor suppressor gene ARHI

Kahkeshan Hijazi (Graduate Student in Bioinformatics, Spira Lab) - Nasal epithelial gene expression profiles reflect dyamic biological response to smoking-cessation

Rebecca Kusko (Graduate Student in Genetics and Genomics, Spira Lab) - Comprehensive genomic profiling of the lung transcriptome in emphysema and IPF using RNA-Seq

Ying Shen (Postdoctoral Fellow, Spira Lab) - Adaptive models for predicting pathway activation and drug response in cancer tissues

GSI 2012 Research Symposium

November 14th, 2012 in Uncategorized

The 2012 Annual Genome Science Institute Research Symposium held on Monday, October 22 was a resounding sucess with participation from both Boston University campuses and seven technology partners.

Seed Grant Recipients for 2012

November 13th, 2012 in Uncategorized

The 2012 Seed Grant Recipients were:

Matthew Jones, PhD, Pulmonary

Collaborators:  Kenneth H. Albrecht, PhD, Medicine, Genetics and Genomic; Caryn L. Navarro, PhD, Medicine


  • To determine whether ZCCHC11 deficiency affects the content level and uridylation of testicular sncRNAs using deep sequencing, mRNA expression using microarrays, and retrotransposon expression using qRT-PCR.
  • To how and when ZCCHC11 deficiency causes germ cell loss leading to infertility by analyzing morphology and marker gene expression in Zcchc11 mutant gonads.

Cesar A. Sommer, PhD, Gastroenterology

Collaborator:  Gustavo Mostoslavsky, PhD, Gastroenterology


  • To interrogate the transcriptome of GIP-expressing K-cells in order to identify genes that define their molecular profile.
  • To investigate the ability of K-cell “identity genes” to modulate the production of GIP and the development of K-cells in vitro.

Sam Thiagalingam, PhD, Biomedical Genetics

Collaborator: Maria I. Ramirez, PhD, Pulmonary Center


  • To test the effect of SDPR over-expression/knock down in in vitro model systems and screening for SDPR expression in tissue microarrays (TMA)
  • In vivo analysis of candidate metastasis suppressor gene, SDPR.