The research in the field of Neuroscience in the Department of Pathology and Laboratory Medicine focuses on mechanisms of brain development and aging and on neurodegenerative and mental illness as well as the brain’s response to trauma. Specifically, Drs. Blusztajn and Mellott pursue studies on the effects of nutrition during early life on brain development and aging as well as on diseases of childhood such as autism. Drs. Blusztajn, Mellott and Slack explore novel growth factor strategies for the treatment of Alzheimer’s disease. Dr. Delalle’s research focuses on abnormalities in microRNA expression in neuropsychiatric disease including schizophrenia and bipolar disorder. Dr. Kowall is the director of the BU ADC Boston University Alzheimer’s Disease Center with vibrant research, clinical and educational programs. Drs. McKee and Goldstein focus their research on long-term sequelae of brain trauma, i.e., chronic traumatic encephalopathy. This research is housed at the Boston University CTE. Training of physician scientists in immunology of brain trauma is supported by a T32 grant from NIH directed by Dr. Remick. Studies involving clinical samples are facilitated by the Biospecimen Archive Research Core (BARC) as well as by several tissue repositories directed by Dr. McKee including the Brain Banks for the BU ADC Boston University Alzheimer’s Disease Center, Chronic Traumatic Encephalopathy Center, Framingham Heart Study, and Centenarian Study. The above-listed faculty collaborate on multiple research projects and participate in graduate student education.