Zhaohua Lu, PhD


Contact Information

email: zaohualu@bu.edu


1996 B.S. China Pharmaceutical University, Nanjing, China; Analytical Chemistry
1999 M.S. China Pharmaceutical University, Nanjing, China; Pharmacology
2004 Ph.D. Kyushu University, Fukuoka, Japan; Chemo-pharmaceutical Sciences
2004-2009 Postdoc fellow Boston University School of Medicine Department of Pathology and Laboratory medicine

Research interests

I have been interested in infectious diseases (hepatitis and tularemia) related mouse models and antibody related therapeutics. I also have experience with antibody development and engineering. I am currently working on B cell epitope discovery and mechanisms of antibody protection in tularemia.

Selected Publications

  1. Roche MI, Lu Z, Hui JH, Sharon J. Characterization of Monoclonal Antibodies to Terminal and Internal O-Antigen Epitopes of Francisella tularensis Lipopolysaccharide. Hybridoma (Larchmt). 2011; 30(1):19-28. PMID: 21466282
  2. Lu Z., Roche M. I., Hui J. H., Unal B., Felgner P. L., Gulati S., Madico G., and Sharon J. Generation and characterization of hybridoma antibodies for immunotherapy of tularemia. Immunol. Letters 2007; 112, 92-103. PMID: 17764754.
  3. Lu Z., Tadashi M., Shoyama Y. and Tanaka H. Construction and expression of a single chain Fv fragment against pharmacologically active paeoniflorin in Escherichia coli, and its potential use in an enzyme-linked immunosorbent assay. Planta Medica 2006; 72(2):151-5.
  4. Lu Z., Morinaga O., Tanaka H. and Shoyama Y. A quantitative ELISA using monoclonal antibody to survey Paeoniflorin and Albiflorin in crude drugs and traditional Chinese herbal medicines. Biol. Pharm. Bull 2003; 26, 862-866. PMID: 12808301.
  5. Xu Q., Lu Z. and Zhang X. A novel role of alkaline phosphatase in protection from immunological liver injury in mice. Liver 2002; 22(1), 8-14.