Dominic Beal



  • September 2008 – present:       PhD  Program – Department of Pathology and Laboratory Medicine
    Boston University School of Medicine, Boston, MA
    Dr. Daniel Remick Lab – Advisor
  • 2006:   Master of Science (Immunology of Infectious Disease)
    London School of Hygiene and Tropical Medicine; England
  • 2004:    Master of Arts (Natural Sciences – Pathology)
    University of Cambridge: Cambridge, England
  • 2000:     GCSE and Advanced Level
    Eastbourne College: Eastbourne, England


Asthma immunology, immune regulation, T-cell subsets


  • Infection with “escaped” virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques. Valentine LE, Loffredo JT, Bean AT, León EJ, MacNair CE, Beal DR, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC, O’Connor DH, Allison DB, Watkins DI.  J Virol. 2009 Nov;83(22):11514-27
  • Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity. Loffredo JT, Sidney J, Bean AT, Beal DR, Bardet W, Wahl A, Hawkins OE, Piaskowski S, Wilson NA, Hildebrand WH, Watkins DI, Sette A. J Immunol. 2009 Jun 15;182(12):7763-75
  • Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication. Loffredo JT, Bean AT, Beal DR, León EJ, May GE, Piaskowski SM, Furlott JR, Reed J, Musani SK, Rakasz EG, Friedrich TC, Wilson NA, Allison DB, Watkins DI. J Virol. 2008 Feb;82(4):1723-38
  • CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. Loffredo JT, Friedrich TC, León EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, Beal DR, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, Wilson NA, Price DA, Kallas EG, Piontkivska H, Hughes AL, Sette A, Watkins DI. PLoS One. 2007 Nov 14;2(11):e1152
  • Mamu-B*08-positive macaques control simian immunodeficiency virus replication. Loffredo JT, Maxwell J, Qi Y, Glidden CE, Borchardt GJ, Soma T, Bean AT, Beal DR, Wilson NA, Rehrauer WM, Lifson JD, Carrington M, Watkins DI. J Virol. 2007 Aug;81(16):8827-32
  • The development of tolerance to Clostridium perfringens type D epsilon-toxin in MDCK and G-402 cells. Beal DR, Titball RW, Lindsay CD. Hum Exp Toxicol. 2003 Nov;22(11):593-605


  • Member of GMSSO at Boston University