JACQUELYN SIKORA

Sikora.Jacjuelyn.ASBMB10a (2)

EDUCATION

  • Sept 2011 – present:   PhD  Program, Department of Pathology and Laboratory Medicine, Boston University  School of Medicine, Boston MA
  • 2011:  BS in Biochemistry, Northeastern University, Boston MA

RESEARCH INTERESTS

I am currently investigating the effects of genetic variation on disease progression of wild-type transthyretin amyloidosis (ATTRwt) in the Amyloid Treatment and Research Program.

PUBLICATIONS

  • Jaylene N. Ollivierre, Jacquelyn L. Sikora, Penny J. Beuning. “Dimer exchange and cleavage specificity of the DNA damage response protein UmuD.” Biochim Biophys Acta. 2013 Feb; 1834(2):611-20. PMID: 23220418
  • Jaylene N. Ollivierre, Jacquelyn L. Sikora, Penny J. Beuning. “The dimeric SOS mutagenesis protein UmuD is active as a monomer.” J Biol Chem. 2011 Feb 4; 286(5):3607-17. PMID: 21118802.

PRESENTATIONS

  • Jacquelyn L. Sikora, Mark W. Logue, Gloria C. Chan, Brian H. Spencer, Tatiana B. Prokaeva, David C. Seldin, Lawreen H. Connors. “Non-coding genetic variation of the transthyretin gene in senile systemic amyloidosis.” International Symposium on Amyloidosis, Indianapolis, IN. April 29, 2014.
  • Jacquelyn L. Sikora, Brian H. Spencer, Tatiana B. Prokaeva, Lawreen H. Connors. “Single nucleotide polymorphisms in the 3’ and untranslated and near gene regions of transthyretin may play a role in senile systemic amyloidosis.” Boston University Medical School Henry I. Russek Day. Boston, MA. May 10, 2013. ASIP, EB Annual Meeting. Boston, MA. April 20-24, 2013. Presented in the general scientific session.
  • Jacquelyn L. Sikora, Jaylene N. Ollivierre, Sarah M. Jensen, Tyler J. Cipriani, Penny J. Beuning. “Heterodimer formation in the DNA damage response protein UmuD.” ASBMB Annual Meeting. Washington, DC. April 9-13, 2011. Northeastern University Research and Scholarship Expo. Boston, MA. April 6, 2011. Northeastern University Board of Trustees Meeting. Boston, MA. May 14, 2011.
  • Jacquelyn Sikora, Ziyong Sun, James Yu, Bo-Sheng Pan, Kallol Ray. “Phosphorylation Status of Select Kinases and its Implications in Inhibitor Discovery.” Merck Research Laboratories Internal Science Symposium. Boston, MA. September 17, 2010.
  • Jacquelyn L. Sikora, Jaylene N. Ollivierre, David E. Budil, Penny J. Beuning. “DNA damage response protein UmuD displays conformational dynamics.” ASBMB Annual Meeting. Anaheim, CA. April 24-28, 2010. Northeastern University Honors Evening. Boston, MA. April 12, 2010.
  • Jacquelyn Sikora, James Yu, Bo-Sheng Pan, Kallol Ray. “Phosphorylation Status of Kinases and its Implications in Inhibitor Discovery.” Merck Research Laboratories Internal Co-op Poster Symposium. Boston, MA. December 11, 2009. Northeastern University Research and Scholarship Expo. Boston, MA. March 24, 2010.

AWARDS/ACCOMPLISHMENTS

  • Amyloidosis Foundation Travel Grant, 2014
  • Graduated magna cum laude from Northeastern University, 2011
  • Honors Junior/Senior Thesis, 2011
  • Undergraduate Outstanding Student Research Award for Physical and Life Sciences, 2011
  • Provost Undergraduate Research Awards, 2008-2011
  • Honors Travel Grant Recipient, 2010
  • Biochemistry Club President, 2008-2011
  • Northeastern University Honors Program, 2008-2011
  • Excellence Scholarship, 2007-2011

 

HOBBIES/INTERESTS

  • Cooking
  • Swimming
  • Yoga
  • Skiing, water and snow
  • Scrapbooking
  • Reading