Past and Present Lab Members
Principal Investigator:
Katya Ravid, DSc, FAAAS and FAHA
Barbara E. Corkey Professor of Medicine; Professor of Biochemistry, Biology, Health Sciences; Founding Director, BU Interdisciplinary Biomedical Research Office (BU IBRO); Founding Director, Evans Center for Interdisciplinary Biomedical Research (ECIBR); Investigator, Whitaker Cardiovascular Institute (WCVI); Boston University Chobanian & Avedisian School of Medicine
Dr. K. Ravid, trained at the Technion and MIT, is an Established Investigator and Fellow of the American Heart Association, has served on editorial and advisory boards and on ASH and Purines Scientific Committees, chaired local and national conferences, such as the Gordon Research Conference on cell biology of megakaryocytes and platelets, and is the recipient of several Awards in recognition of research and teaching, such as Boston University Chobanian & Avedisian School of Medicine (CAMed) Educator of the Year Award in Graduate Medical Sciences, Sidney University Professorship Award, the Weizmann Institute Rosi and Max Varon Professorship Award, and as a long-standing ASMBM member was awarded the Fulbright Scholar Award.
Founding Director, Evans Center for Interdisciplinary Biomedical Research (http://www.bumc.bu.edu/evanscenteribr/)
Training Program Director, NHLBI-funded Training Program in Cardiovascular Biology (www.bumc.bu.edu/cardiograd)
Quote:
“Rewarding science is born out of creativity, tenacity and generosity.”
(Katya Ravid)
Past and Current Trainees
Past and Current Trainees |
Pre (PhD training) or Post-doctoral |
Training Period | Prior Academic Degree | Title of Research Project | Current Position (past trainees) Source of Support (current trainees) |
|||||
| Degree(s) | Year(s) | Institutions(s) | ||||||||
| Chen, Wen-Chen
|
Pre |
1994-1997 |
MS |
1994 |
Harvard School of Public Health |
Thrombopoietin-inducible genes |
Research Associate, Dana Farber Cancer Institute, HMS, Boston, MA; then Dental school, Dentist in CA |
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| Frances, Cynthia
|
Post | 1996-2000 | PhD | 1996 | Boston University School of Medicine | Adenosine receptors in platelets and vascular smooth muscle | Senior Researcher and then consultant, Proctor & Gamble (until 2015; retired) | |||
| Sun, Shinshin (Ivon)
|
Post | 1995-1999 | PhD | 1995 | St. John University, NY | Regulation of the endomitotic cell cycle in megakaryocytes | Assistant Professor, North Shore-Long Island Jewish Research Institute Phytochemical Lab, Manhasset, NY | |||
| Thompson, Alex*
|
Pre | 1995-1999 | MS | 1990 | University of Coleraine, Ireland | Regulation of endomitosis in megakaryocytes | Associate Professor in Translational Stem Cell Technology, Division of Cancer and Stem Cells, Wolfson Centre for Stem Cells, Tissue Engineering & Modelling (STEM), Centre for Biomedical Sciences, University of Nottingham, UK | |||
| Zhao, Zhihui
|
Post
|
1994-2000 | MD, PhD | 1993
|
Beijing Med. Univ., China | Adenosine receptors in platelets and vascular smooth muscle | Sr. Director, Antibody & Protein Discovery, QLB Bio-therapeutics Inc. (2017-present); Sr. Scientist, Bioscience Technologies, Inc, Waltham, MA; (2008-2017); Assistant Professor of Medicine, BU CAMed (2002-2008) | |||
| Zimmet, Jeffrey*
|
Pre P
(MD/PhD) |
1995-1998 | BS | 1993
|
Wesleyan Univ., CT | Regulation of the endomitotic cell cycle in megakaryocytes | Professor of Medicine (tenured), Univ California San Francisco; Interventional Cardiology, San Francisco VAMC | |||
| Cataldo, Leah
|
Post | 1995-1997 | PhD | 1995 | University of Massachusetts | Thrombopoietin-induced genes | Science Department Dean, Buckingham Browne & Nichols School, Cambridge, MA | |||
| Hechler, Beatrice
|
Post | 1998-2000 | PhD
|
1998
|
INSERM U.311
Etablissement Français du Sang-Alsace Strasbourg, FR. |
Overexpression of the P2Y1 receptor specifically in megakaryocytes and platelets from transgenic mice | Group Leader, INSERM, University of Strasbourg, France | |||
| Pierron, Anne
|
Pre
(MA) |
2001 | BA | Unknown | University of Nice,
France |
Effect of adenosine analogs on cell growth | Regulatory Affairs at Virbac;
Research Associate, University of Nice, France |
|||
| Jones, Matthew* P
|
Pre P | 1999-2003 | BA | 1996
|
University of Delaware | Regulation of ploidy in vascular smooth muscle and megakaryocytes | Assistant Professor; Director, Molecular Medicine Graduate Program, and leading training program within BU CTSI, BU CAMed | |||
| Kaluzhny, Yulia
|
Pre | 1996-2001 | MS | 1990 | Moscow State Institute, Moscow, USSR | Lineage determination and apoptosis of megakaryocytes | Principal Scientist, MatTek Corp., Ashland, MA | |||
| Lu, Jun*
|
Pre | 1997-2003 | MSc | 1996 | Nanjing University, Nanjing, P.R. China | Nucleosome assembly proteins in hematopoiesis | Associate Professor Genetics (tenured), Yale Dept of Genetics and Stem Cell Center | |||
| Wang, Zenhngyu (Zack) *
|
Pre | 1994-1998 | BS | 1990 | East China University of Chem. Technology
|
Transcriptional regulation of cyclin D3 in megakaryocytes; implication for cell maturation and platelet production | Director, Ross flow cytometry core Associate Professor Division of Hematology, Johns Hopkins Medicine,Center for Molecular Medicine Maine Medical Center Research Institute (until 2012) |
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| Yaar, Ron
|
Pre
(MD/PhD) |
1998-2002 | BSc | 1996 | Boston University
|
Regulation of expression of the A3 adenosine receptor in the vasculature | Dermatopathologist at Muhlbauer Dermatopathology Lab, Rochester, New York Area (July 2016 – present); Senior Pathologist, Aurora Diagnostics, North Carolina (until 2016); (until 2010 was Assistant Professor, Director of Resident and International Dermatopathology Training Dermato-pathology, Boston Medical Center) |
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| Zhang, Ying*
|
Pre | 1998-2003 | MSc | 1988 | Univ. Science & Technol, Hefei, China, BSC, 1979, Shanghai Inst. of Biochemistry | Mechanism of thrombopoietin effect on platelet development | CEO of a Biotech start up in China (former Instructor of Medicine, BU CAMed) | |||
| Dharmaraj, Chinnapen
|
Post | 1999-2000 | PhD | 1994 | All India Institute of Medical Sciences, New Delhi, India | Regulation of polyploidy during hematopoiesis | Senior Researcher, Sema4, A Spin-off Company of the Mount Sinai Health System; Previously at Florida Cancer Specialists and Research Institute, Fort Myers, Florida | |||
| Nguyen, Hao*
|
Pre
(MD/PhD) |
2001-2005 | BA | 1999 | Univ. of Cal. Berkeley | The regulation of Aurora-kinase stability and its role in polyploidization and transformation | (tenured) Associate Professor, Richard and Leilani Endowed Professorship in Urology,UCSF Department of Urology;formerly Clinical Fellow, (Resident in Surgery until 2014), Univ. California Davis Medical Center | |||
| Yu, Guangyao
|
Pos | 2000-2002 | MD, PhD | 1997 | Henan Medical University, Zhengzhou, Henan, China (MD; Tongji Medical University, China (PhD) | Control of megakaryocyte ploidy and apoptosis | Research Scientist, Tetralogic Pharmaceuticals, Malvern, PA
|
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| St.Hilaire, Cynthia*
|
Pre | 2004-2008 | BS | 2001 | Univ. of Vermont | Adenosine receptor function in the vasculature | Associate Professor of Cardiology (tenured), Vascular Medicine Institute, University of Pittsburgh; (Postdoctoral Fellow, NHLBI till 2015); Associate Editor, Circulation Research journal (2023) | |||
| McCrann, Donald Jr. *
|
Pre P | 2004-2008 | BS | 2001 | Yale University | Polyploidy and vascular function | Research Group Leader, IDEXX Laboratories, Westbrook, ME; (Postdoctoral Fellow, Maine Medical Research Center (until 2011) | |||
| Liu, Kenian
|
Post | 2005-2006 | PhD | 2002 | Univ. of Arkansas
Med Sci, |
Hematopoiesis and ploidy regulation | Assistant Professor, Moffitt Cancer Center &University of South Florida (prior: Researcher, UMDNJ, Center for Human and Molecular Genetics, Newark, NJ) | |||
| Makitalo, Maria
|
Pre
(MA courses) |
2005-2007 | MA | 2004 | Sweden | Transcriptional signatures in lineage restricted genes | PhD researcher, Sweden | |||
| Yang, Dan
|
Post |
2004-2009 |
MD,PhD |
2002 |
San Yat-Sen and Hunan Univ., China | The role of A2b adenosine receptors in inflammation and vascular pathology | Senior Staff Scientist, NHLBI | |||
| Papadantonakis, Nikolaos
|
Pre | 2007-2010 | MD | 2006 | University of Crete | Regulation of polyploidy in bone marrow cells | Assistant Professor Emory Clinic, Emory Winship Cancer Institute, Atlanta, GA; Assistant Prof Hematology/ Oncology, Univ of Alabama Med School; Formerly Hem/Onc Fellow, Cleveland Clinic | |||
| Burridge, Kelley | Post | 2010 | PhD | 2007 | Boston University | Oxidative Stress and megakaryocyte polyploidy | Investigator, FDA | |||
| Eliades, Alexia*
|
Pre | 2007-2011 | BA | 2005 | University of Athens Greece | Bone marrow megakarypoiesis | Group Leader, University of Cyprus, Greece; (before that: Research Associate,University of Manchester, England) | |||
| Chen, Hongjie
|
Post | 2007-2011 | PhD | 2000 | Chinese Academy of Sciences | The role of adenosine receptors is angiogenesis | Assistant Professor and Assistant Director, Clinical Genetics, Mt. Sinai Medical School, NY | |||
| Koupenova-Zamor, Milka*
|
Pre;
Then Post |
2005-2010 (Pre); 2010-2011 (post) | BS | 2003 | Univ. of Cal.
Los Angeles |
The role of A2b adenosine receptors in vascular proliferation | Assistant Professor of Medicine, Cardiology Section, University of Mass Medical School; Associate Editor, Circulation Research journal (2023) | |||
| Bhupatiraju, Ajoy V | Post | 2010-present | PhD | 2006 | India Tech Inst | Oxidase control of megakaryo-poiesis | Head, Dept. of Microbiology, Regional Research and analytical Laboratory, A division of Ananda Enterprises (India) Pvt. ltd,, AndhraPradesh, India | |||
| Johnston-Cox, Hlillary*
|
Pre (MD/PhD) | 2009-2014 | BS | 2007 | Univ. of Cal. San Diego | The role of A2b adenosine receptors in vascular disease | Assistant Professor Cardiology, Zucker School of Medicine, at Hofstra/ Northwell | |||
| Carroll, Shannon*
|
Pre | 2009-2013 | BS, MA | 2004,
2007 |
University of Arizona | Adenosine receptors and stem cell niche | Instructor of Surgery, Harvard Medical School | |||
| Eisenstein, Anna* | Pre (MD/PhD) | 2010-2014 | BA | 2008 | Middlebury College | Adenosine receptors and mesenchymal stem cell differentiation | Assistant Professor Dermatology, Yale School of Medicine; Director, Hidradenitis Suppurativa Clinic, Tufts Medical Center | |||
| Mi, Rongjuan | Post | 2012-2015 | PhD | 12/2008 | Clemson University, Clemson, South Carolina
|
Control of BM matrix by megakaryocyte LOX
|
Research Scientist, BU Dental School | |||
| Patterson, Shenia | Pre (MD/PhD) | 2012-2016 | BS | 2010 | Spelman College, Atlanta | Molecular mechanisms of effects of adenosine on vascular tone | Medical Resident (Internal Medicine), University of South Carolina (MUSC) in Charleston, SC | |||
| Lieva, Orly | Medical Student (MD) | 2016-2018 | BS | 2013 | Wright State University, Magna Cum Laude | Control of Bone marrow cell stem-induced myelofibrosis | Cardiology Fellow, NYU; Medical Resident, Harvard Med School and BWH; 2016 Alpha Omega Alpha Carolyn L. Kuckein Student Research Fellowship; 2016 ASH Hematology Opportunities for the Next-Generation of Research Scientists (HONORS) Award | |||
| Ng, Seng Kah | Post Doc | 2016-2018 | PhD | 2010 | Temasek Life Science Laboratory / National University of Singapore | Mechanosensing and megakaryocyte properties | Scientist, ALSTEM, INC, San Pablo, California | |||
| Walker, Joshua | Post Doc | 2016-present | PhD | 2016-2020 | Boston College | LOX and uremic solutes control of thrombosis | Senior Researcher, Pfizer (MA branch) | |||
| Mazzeo, Carla | Post | 2018-2020 | PhD | 2010 | Autonomous University of Madrid | Megakaryocyte mechanosensor proteins | Sr Research Development Scientist, Boston Medical Center | |||
| Ward, Christina | Post | 2018-2020 | PhD | 2016 | Augusta University | Matrix Mechanosensing by megakaryocytes | Research Scientist, Gene Therapy Analytical Development, Sarepta Therapeutics, Andover MA | |||
| Thompson, Cristal | Post | 2018-2020 | PhD | 2018 | University of Notre Dame | Primary myelofibrosis and thrombosis | Manager/Scientific Consultant, Genedata, Inc, Lexington, MA | |||
| Gaye, Maissa
|
Post (PhD) | 2019-2021 | PhD | 2015 | Indiana University, Bloomington, IN | Primary myelofibrosis: Proteomics | Senior scientist, Chemistry R&D, Waters Corp, Milford MA | |||
| Lucero, Hector | Research Associate | 2014-present (part time) | PhD | 1990 | University of Buenos Aires Argentina | Control of Bone marrow matrix by megakaryocyte LOX
|
In Dr. Ravid’s lab (part time) | |||
| Matsuura, Shinobu | Post | 2011-2016 Post Doc;
2016-present |
DVM, PhD | 2006 | DVM: Universidade de Sao Paulo; PhD: University of Tokyo |
Megakaryocyte adhesion properties and significance for myelofibrosis | Assistant Professor of Medicine, BU CAMed
In Dr. Ravid’s lab |
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| Karagianni, Katerina
|
Pre (PhD) | 2018-2023 | MS | 2018 | University of Crete, Greece | Megakaryocyte specific KO of LOX- implications for bone and PMF | Research Scientist; Biohaven, MA | |||
| Yang, Xiaosheng
|
Pre | 2021-2023 | MS | 2020 | Boston University School of Medicine | Megakaryocyte integrin biology in PMF | PhD Student, Tufts Medical School, Boston, MA |
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| Huang, Nasi
|
Post | 2021- | MD | 2010 | Jinan University School of Medicine, Guangzhou, China | Megakaryocyte mechanosensing | In Dr. Ravid’s lab | |||
| Karkempetzaki, Anastasia Iris | Pre- | 2022- | M.Sc. B.Sc. |
2022
2020 |
School of Medicine, University of Crete, Greece
School of Life Sciences, University of Athens, Greece |
Piezo1 in Mega-karyocyte & Platelet Development | In Dr. Ravid’s lab | |||
| Stern, Andrea L Rier
|
Undergraduate | Summer 2005 | BS | 2006 | Virginia University | Adenosine analogs and cell cycle inhibition | Practicing Family Medicine, (trained at Lancaster General Hospital, Lancaster, PA) | |||
| Piasecki, Andrew | Undergraduate | 2019-2021 | BS | 2015 | Boston University | Impact of JAK2 on ß1 integrin r/t Proteomics of mutated megakaryocytes | Pursuing PhD, Northeastern University, Boston, MA | |||
(*) Award Recipients
Students from Greece in Dr. Ravid’s lab; Starting in 2012
| Student Name: | Summer spent in lab: | School attended in Greece |
| Alexandra Koutsolelou | summer of 2012 | University of Athens, Biology |
| Efstratios Kofopoulos – Lymperis | summer of 2012 | University of Crete, Medicine |
| Emmanouela Tsagkaraki | summer of 2013 | University of Crete, Medicine |
| Michail Kontakis | summer of 2013 | University of Crete, Medicine |
| George Kalarakis | summer of 2014 | University of Crete, Medicine |
| Eleni Terezaki | summer of 2014 | University of Crete, Medicine |
| Eugenia Stagaki | summer of 2019 | University of Crete, Medical School (via Dr. Dimitris Kardassis) |