Representative Recent Publications:Screen Shot 2016-03-17 at 5.50.40 PM

An updated (every 3-6 months) list of publications can be found in: 

Highlights of Ravid’s lab contribution to the field of polyploidy in context of platelets and vascular function, podcasted in a Science editorial interview article (Science vol 343 14, Feb 2014, page 725):

Press Releases: 

New drugs for myelofibrosis as basis for a clinical trial

Researchers identify two drugs that delay bone marrow cancer development

To read more see the featured article on the BU School of Medicine page as well as News Break and also referenced in a March 22, 2021, posting by


New possible treatment approach to primary myelofibrosis

Researchers Attempt New Treatment Approach for Blood Cancer

Discovering new Paths to Thrombosis published in Science Translational Medicine:

Understanding a Therapeutic “Paradox” for Treating Thrombo-Vascular Complications in Kidney Disease


Discovery of a new pathway involved in control of thrombosis:

Researchers Discover Key Pathway Involved in Blood Vessel Occlusion

Researchers discover key pathway involved in blood vessel occlusion

Key pathway involved in blood vessel occlusion discovered


Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

BUSM study identifies Adenosine Receptor’s role in regulating high fat diet-induced obesity and Type 2 Diabetes

Study identifies receptor’s role in regulating obesity, type 2 diabetes

Blood Cover, Volume 116, Number 12, Sept 2010.

Representative Reviews:

Emerging Factors Implicated in Fibrotic Organ-Associated Thrombosis: The Case of Two Organs. Leiva O, Bekendam RH, Garcia BD, Thompson C, Cantor A, Chitalia V, Ravid K. TH Open. 2019 Apr; 3(2):e165-e170.View Related Profiles. PMID: 31259299

Matrix Mechanosensation in the Erythroid and Megakaryocytic Lineages. Ward CM, Ravid K. Cells. 2020 Apr 06; 9(4).View Related Profiles. PMID: 32268541

The role of extracellular matrix stiffness in megakaryocyte development and function. Leiva O, Leon C, Kak Ng S, Mangin P, Gachet C, Ravid KAm J Hematol. 2018 Mar;93(3):430-441. doi: 10.1002/ajh.25008. Epub 2018 Jan 12. Review.

Biology of Platelet Purinergic Receptors and Implications for Platelet Heterogeneity. Koupenova M, Ravid K.
Front Pharmacol. 2018 Jan 30;9:37. doi: 10.3389/fphar.2018.00037. eCollection 2018. Review.

The role of the extracellular matrix in primary myelofibrosis. Leiva O, Ng SK, Chitalia S, Balduini A, Matsuura S, Ravid K. Blood Cancer J. 2017 Feb 3;7(2):e525. doi: 10.1038/bcj.2017.6. Review.

The Many Faces of the A2b Adenosine Receptor in Cardiovascular and Metabolic Diseases. Eisenstein A, Patterson S, Ravid K. J Cell Physiol. 2015 Dec;230(12)2891-7. doi: 10.1002/jcp.25043. Review.

G protein-coupled receptors and adipogenesis: a focus on adenosine receptors. Eisenstein A, Ravid K. J Cell Physiol. 2014 Apr;229(4):414-21. doi: 10.1002/jcp.24473. Review.

Regulation of atherosclerosis and associated risk factors by adenosine and adenosine receptors. Koupenova M, Johnston-Cox H, Ravid K. Curr Atheroscler Rep. 2012 Oct;14(5):460-8. doi: 10.1007/s11883-012-0263-y.

A2 adenosine receptors and vascular pathologies. Johnston-Cox HA, Koupenova M, Ravid K. Arterioscler Thromb Vasc Biol. 2012 Apr;32(4):870-8. doi: 10.1161/ATVBAHA.112.246181. Review.

Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection. Papadantonakis N, Matsuura S, Ravid K. Blood. 2012 Aug 30;120(9):1774-81. doi: 10.1182/blood-2012-02-402594. Epub 2012 Jul 5. Review.

Oxidases and reactive oxygen species during hematopoiesis: A focus on megakaryocytes. Eliades A, Matsuura S, Ravid K. J Cell Physiol. 2012 Fab 13. doi: 10.1002/jcp.24071.

Adenosine and Blood Platelets. Johnston-Cox H and Ravid K. Purinergic Signalling. 2011 Sept;7(3):357-65.

Physiological Implications of Adenosine Receptor-Mediated Platelet Aggregation. Johnston-Cox H, Yang D, Ravid K. J Cell Physiol. 2011 Jan;226(1):46-51.

Mechanisms of induction of adenosine receptor genes and its functional significance. St Hilaire C, Carroll SH, Chen H, Ravid K. J Cell Physiol. 2009 Jan;218(1):35-44. Review. PMID: 18767039 [PubMed – indexed for MEDLINE]

Vascular smooth muscle cell polyploidy: an adaptive or maladaptive response? McCrann DJ, Nguyen HG, Jones MR, Ravid K. J Cell Physiol. 2008 Jun;215(3):588-92. Review. PMID: 18181174 [PubMed – indexed for MEDLINE]

Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins. Nguyen HG, Ravid K. J Cell Physiol. 2006 Jul;208(1):12-22. Review. PMID: 16331679 [PubMed – indexed for MEDLINE]

Animal models for the study of adenosine receptor function. Yaar R, Jones MR, Chen JF, Ravid K. J Cell Physiol. 2005 Jan;202(1):9-20. Review. PMID: 15389588 [PubMed – indexed for MEDLINE]

Role of apoptotic processes in platelet biogenesis. Kaluzhny Y, Ravid K. Acta Haematol. 2004;111(1-2):67-77. Review. PMID: 14646346 [PubMed – indexed for MEDLINE]

Roads to polyploidy: the megakaryocyte example. Ravid K, Lu J, Zimmet JM, Jones MR. J Cell Physiol. 2002 Jan;190(1):7-20. Review. PMID: 11807806 [PubMed – indexed for MEDLINE]

Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system. Zimmet J, Ravid K. Exp Hematol. 2000 Jan;28(1):3-16. Review. PMID: 10658672 [PubMed – indexed for MEDLINE]