New Research Identifies Signals Controlling Goblet Cells in the Lung

Associate Professor Bob Varelas and colleagues have discovered that goblet cell numbers in the airways are governed by Yap and Taz transcription factors. Because goblet cells and the mucus they produce are excessive in many chronic lung diseases (such as COPD, asthma, and cystic fibrosis), this new understanding of the signaling pathways determining goblet cell […]

Recent Awards for Trainees

Congratulations to these Pulmonary Center trainees who were recently successful in receiving extramural training awards: Claire Burgess Ph.D. Student, Mentor: Darrell Kotton NIH F31 Predoctoral Fellowship Award “Generation of human alveolar epithelial type I cells from pluripotent stem cells” Senegal Carty Ph.D. Student, Mentor: Matt Jones American Heart Association Predoctoral Fellowship Award “Pulmonary Lymphatic Endothelial […]

2021 ATS Awards

Justin Lui, M.D. Pulmonary Fellow, Mentor: Klings/Wiener 2021 ATS Ziskind Clinical Research Scholar Award “The Ziskind Clinical Research Scholar Award is an ATS Scholarship Award that honors pulmonary and critical care fellows engaged in clinical research. The award was named after Morton Ziskind, MD, a highly respected clinician-researcher from Tulane University who died in 1979 […]

PhD Candidate Kiloni Quiles-Franco Featured in Podcast Interview

Kiloni Quiles-Franco is a PhD candidate in the labs of Felicia Chen MD in the Pulmonary Center and Evan Johnson PhD in the Division of Computational Biomedicine at Boston University School of Medicine. Kiloni is engaged in a number of on- and off-campus initiatives focused on equity and inclusion, such as the Women’s Professional Development […]

New ways to attack necrotic tuberculous granulomas in the lung

Approximately one quarter of all humans have been infected during their lifetime with Mycobacterium tuberculosis – the bacteria that causes tuberculosis (TB). Most of the infected people control the bacteria that remain dormant for many years. In some individuals, however, the bacteria grow in the lungs, causing severe lung damage, including the formation of necrosis […]

Dr. O’Connor and the New Asthma Guidelines

George O’Connor, MD, MS, a Pulmonary Center faculty member and associate editor of JAMA, and Stephanie Lovinsky-Desir, MD, MS from Columbia University, wrote an editorial (1) in the December 8, 2020 issue of JAMA on a new update to the NIH asthma guidelines (2) that was also published in that issue of JAMA. Drs. O’Connor […]

Actionable Lung Cell Responses to SARS-CoV-2 Infection

      Teams from Pulmonary Center Faculty members Andrew Wilson and Darrell Kotton (and collaborators) recently published exciting new findings about how alveolar epithelial type 2 cells respond to SARS-CoV-2 infection!     “Briefly, we found that there are changes to cellular proteins (the proteome and phosphoproteome) that occur as soon as 1 hour […]

COVID-19 study spanning 275 hospitals and 23 countries

Dr. Walkey is co-Principal Investigator for the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study. This study, funded in part by the Gordon and Betty Moore Foundation, created an international registry that supplies de-identified clinical data from more than 40,000 patients at 275 hospitals in 23 countries for the conduct […]