Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer’s disease
Abstract Introduction: The genetic basis of Alzheimer’s disease (AD) in Koreans is poorly understood. Methods: We performed an AD genome-wide association study using whole-genome sequence data from 3540 Koreans (1583 AD cases, 1957 controls) and single-nucleotide polymorphism array data from 2978 Japanese (1336 AD cases, 1642 controls). Significant findings were evaluated by pathway enrichment and differential gene […]