Publications
Welcome to the publications page of the Framingham Heart Study Brain Aging Program (FHS-BAP), where we showcase the groundbreaking research driving advancements in Alzheimer’s Disease (AD) understanding. Our program is committed to revolutionizing AD research through a comprehensive approach that integrates surveillance, discovery, and collaboration. Here, you will find our latest publications, which reflect our work in enhancing cognitive decline assessments, brain imaging techniques, and the revitalization of our brain donation program. These publications highlight key findings in genetic factors, risk markers, and biomarkers related to AD, all aimed at fostering a global research community and accelerating the identification of therapeutic targets. Explore our research to learn more about our mission to uncover the biological foundations of AD and contribute to the preservation of cognitive health.
Automated detection of mild cognitive impairment and dementia from voice recordings: A natural language processing approach
Amini S, Hao B, Zhang L, Song M, Gupta A, Karjadi C, Kolachalama VB, Au R, Paschalidis IC. Automated detection of mild cognitive impairment and dementia from voice recordings: A natural language processing approach. Alzheimers Dement. 2022. doi: 10.1002/alz.12721. Epub ahead of print. PMID: 35796399. Read More
Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer’s disease among women
Chung J, Das A, Sun X, Sobreira D, Leung YY, Iguarta C, Mozaffari, Chou Y-F, Thiagalingam S, Mez J, Zhang X, Jun GR, Stein TD, Kunkle B, Martin ER, Pericak-Vance MA, Mayeux R, Haines JL, Schellenberg G, Nobrega M, Lunetta KL, Pinto JM, Wang L-S, Ober C, Farrer LA. Genome-wide... More
Multimodal deep learning for Alzheimer’s disease dementia assessment
Qiu S, Miller MI, Joshi PS, Lee JC, Xue C, Ni Y, Wang Y, De Anda-Duran I, Hwang PH, Cramer JA, Dwyer BC, Hao H, Kaku MC, Kedar S, Lee PH, Mian AZ, Murman DL, O’Shea S, Paul AB, Saint-Hilaire MH, Sartor EA, Saxena AR, Shih LC, Small JE, Smith... More
Cross-Sectional Association Between Blood Cell Phenotypes, Cognitive Function, and Brain Imaging Measures in the Community-Based Framingham Heart Study
Fang Y, Doyle MF, Alosco ML, Mez J, Satizabal CL, Qiu WQ, Lunetta KL and Murabito JM: Cross-sectional association between blood cell phenotypes, cognitive function and brain imaging measures in the community-based Framingham Heart Study. J Alzheimers Dis. 2022; 87(3):1291-1305. Read More
Interface astrogliosis in contact sport head impacts and military blast exposure
Babcock KJ, Abdolmohammadi B, Kiernan PT, Mahar I, Cherry JD, Alvarez VE, Goldstein LE, Stein TD, McKee AC, Huber BR. Interface astrogliosis in contact sport head impacts and military blast exposure. Acta Neuropathol Commun. 2022 Apr 13;10(1):52. Read More